A comprehensive herbal medicine information system for cancer (CHMIS-C)
has been developed. The current version of the database integrates
information on 203 cancer related molecular targets, 527 anticancer herbal recipes that have been used
for the treatment of different types of cancer in clinic, 937 individual
ingredients, and 9366 small organic molecules isolated from herbal
medicines. Furthermore, subsidiary databases of literature references and
molecular targets have been constructed. A number of web-based searching
tools have been developed and integrated into the information system for
efficient data mining. The compounds in the database have been linked to
the corresponding entries in the National Cancer Institute's database, and
to a database of drugs approved by the U.S. Food and Drug Administration. CHMIS-C provides a description of the individual subsidiary databases,
integration of the entire database, and data mining tools. We demonstrate
that this comprehensive information system may be used as an effective
informatics tool for anticancer drug discovery.
CHMIS-C:
A Comprehensive Herbal Medicine Information System for Cancer Fang, X.; Shao, L.;
Zhang, H.; Wang, S.*; J. Med. Chem.;(Article); 2005;
48(5); 1481-1488.
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