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AplidinTM induces apoptosis in human cancer cells via glutathione depletion and sustained activation of epidermal growth factor receptor, Src, Jun N-terminal kinase and p38 kinase.
J Biol Chem. 2002 Oct 31 [epub ahead of print]
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2: Meves A, Stock SN, Beyerle A, Pittelkow MR, Peus D. Related Articles, Links
H(2)O(2) mediates oxidative stress-induced epidermal growth factor receptor phosphorylation.
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3: Chien HH, Lin WL, Cho MI. Related Articles, Links
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4: Bradford PG, Maglich JM, Ponticelli AS, Kirkwood KL. Related Articles, Links
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5: Iznaga Escobar N, Morales A, Nunez G. Related Articles, Links
A computer program for quantification of SH groups generated after reduction of monoclonal antibodies.
Nucl Med Biol. 1996 Jul;23(5):635-9.
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Time used: 78 miliseconds.

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