1: Asante-Appiah E, Patel S, Dufresne C, Roy P, Wang Q, Patel V, Friesen RW, Ramachandran C, Becker JW, Leblanc Y, Kennedy BP, Scapin G. Related Articles, Links
The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates.
Biochemistry. 2002 Jul 23;41(29):9043-51.
PMID: 12119018 [PubMed - indexed for MEDLINE]
2: Gugliucci A, Ranzato L, Scorrano L, Colonna R, Petronilli V, Cusan C, Prato M, Mancini M, Pagano F, Bernardi P. Related Articles, Links
Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors.
J Biol Chem. 2002 Aug 30;277(35):31789-95.
PMID: 12080072 [PubMed - indexed for MEDLINE]
3: Leung C, Grzyb J, Lee J, Meyer N, Hum G, Jia C, Liu S, Taylor SD. Related Articles, Links
The difluoromethylenesulfonic acid group as a monoanionic phosphate surrogate for obtaining PTP1B inhibitors.
Bioorg Med Chem. 2002 Jul;10(7):2309-23.
PMID: 11983529 [PubMed - indexed for MEDLINE]
4: Wohlrab H, Annese V, Haefele A. Related Articles, Links
Single replacement constructs of all hydroxyl, basic, and acidic amino acids identify new function and structure-sensitive regions of the mitochondrial phosphate transport protein.
Biochemistry. 2002 Mar 5;41(9):3254-61.
PMID: 11863464 [PubMed - indexed for MEDLINE]
5: Phelps A, Briggs C, Haefele A, Mincone L, Ligeti E, Wohlrab H. Related Articles, Links
Mitochondrial phosphate transport protein. Reversions of inhibitory conservative mutations identify four helices and a nonhelix protein segment with transmembrane interactions and Asp39, Glu137, and Ser158 as nonessential for transport.
Biochemistry. 2001 Feb 20;40(7):2080-6.
PMID: 11329276 [PubMed - indexed for MEDLINE]
Time used: 62 miliseconds.

Webpage designed by Dr. Xueliang Fang, last updated on 3/10/2005