ID Name Structure References (top 5) Molecular Target(s)
1ID:1033
CHOLIC ACID


NSC#:6135
NSC#:657947
Aldrich#:135240
Aldrich#:27010
Aldrich#:C1129
Aldrich#:R203572

Freqency:
in 1 ingredients:

  • 52
  • in 8 recipes:

  • 2
  • 12
  • 100
  • 125
  • 205
  • 217
  • 271
  • 380

  • Properties
    C24H40O5    408.58





    1:  Setchell KD, Heubi JE, Bove KE, O'Connell NC, Brewsaugh T, Steinberg SJ, Moser A, Squires RH Jr.
    Liver disease caused by failure to racemize trihydroxycholestanoic acid: gene mutation and effect of bile acid therapy.
    Gastroenterology.    impact factor:   12.182
    2003;  124(1): 217-32

    2:  Moore DD.
    Does loss of bile acid homeostasis make mice melancholy?
    J Clin Invest.    impact factor:   10.921
    2002;  110(8): 1067-9

    3:  Li-Hawkins J, Gafvels M, Olin M, Lund EG, Andersson U, Schuster G, Bjorkhem I, Russell DW, Eggertsen G.
    Cholic acid mediates negative feedback regulation of bile acid synthesis in mice.
    J Clin Invest.    impact factor:   10.921
    2002;  110(8): 1191-200

    4:  Willemen HM, de Smet LC, Koudijs A, Stuart MC, Heikamp-de Jong IG, Marcelis AT, Sudholter EJ.
    Micelle formation and antimicrobial activity of cholic Acid derivatives with three permanent ionic head groups.
    Angew Chem Int Ed Engl.    impact factor:   7.996
    2002;  41(22): 4275-7

    5:  Chen JY, Levy-Wilson B, Goodart S, Cooper AD.
    Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet.
    J Biol Chem.    impact factor:   7.666
    2002;  277(45): 42588-95

     
    Time used: 140 milliseconds.

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