ID Name Structure References (top 5) Molecular Target(s)
1ID:1396
CYCLEANINE


NSC#:615580(<1uM)

Freqency:
in 6 ingredients:

  • 98
  • 308
  • 369
  • 372
  • 374
  • 477
  • in 24 recipes:

  • 1
  • 3
  • 16
  • 30
  • 38
  • 50
  • 55
  • 71
  • 81
  • 82
  • 84
  • 86
  • 91
  • 108
  • 113
  • 115
  • 121
  • 156
  • 160
  • 182
  • 193
  • 390
  • 476
  • 519

  • Properties
    C38H42N2O6    622.76





    1:  Kondo Y, Takano F, Hojo H.
    Inhibitory effect of bisbenzylisoquinoline alkaloids on nitric oxide production in activated macrophages.
    Biochem Pharmacol.    impact factor:   2.755
    1993;  46(11): 1887-92

    2:  Kondo Y, Takano F, Hojo H.
    Suppression of lipopolysaccharide-induced fulminant hepatitis and tumor necrosis factor production by bisbenzylisoquinoline alkaloids in bacillus Calmette-Guerin-treated mice.
    Biochem Pharmacol.    impact factor:   2.755
    1993;  46(10): 1861-3

    3:  Fournet A, Inchausti A, Yaluff G, Rojas De Arias A, Guinaudeau H, Bruneton J, Breidenbach MA, Karplus PA, Faerman CH.
    Trypanocidal bisbenzylisoquinoline alkaloids are inhibitors of trypanothione reductase.
    J Enzyme Inhib.    impact factor:   1.733
    1998;  13(1): 1-9

    4:  Angerhofer CK, Guinaudeau H, Wongpanich V, Pezzuto JM, Cordell GA.
    Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids.
    J Nat Prod.    impact factor:   1.652
    1999;  62(1): 59-66

    5:  Kashiwaba N, Ono M, Toda J, Suzuki H, Sano T.
    Synthesis of Cycleanine Mono-N-oxides
    J Nat Prod.    impact factor:   1.652
    1998;  61(2): 253-5

     
    Time used: 515 milliseconds.

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