ID Name Structure References (top 5) Molecular Target(s)
1ID:2073
EMODIN


NSC#:408120
NSC#:622947
Aldrich#:230510
Aldrich#:45170
Aldrich#:E171
Aldrich#:E7881

Freqency:
in 10 ingredients:

  • 14
  • 118
  • 120
  • 127
  • 139
  • 157
  • 250
  • 251
  • 481
  • 622
  • in 100 recipes:

  • 3
  • 4
  • 6
  • 17
  • 26
  • 28
  • 31
  • 32
  • 36
  • 43
  • 50
  • 53
  • 57
  • 62
  • 79
  • 97
  • 98
  • 103
  • 112
  • 114
  • 118
  • 122
  • 138
  • 140
  • 145
  • 150
  • 152
  • 154
  • 155
  • 156
  • 157
  • 162
  • 164
  • 165
  • 166
  • 168
  • 196
  • 206
  • 208
  • 209
  • 210
  • 219
  • 222
  • 226
  • 228
  • 231
  • 235
  • 245
  • 246
  • 249
  • 250
  • 254
  • 255
  • 262
  • 263
  • 265
  • 267
  • 274
  • 278
  • 280
  • 281
  • 284
  • 288
  • 289
  • 291
  • 293
  • 297
  • 300
  • 305
  • 308
  • 310
  • 313
  • 315
  • 320
  • 338
  • 340
  • 357
  • 364
  • 377
  • 378
  • 383
  • 386
  • 389
  • 395
  • 401
  • 409
  • 411
  • 415
  • 421
  • 428
  • 434
  • 435
  • 436
  • 437
  • 438
  • 439
  • 445
  • 446
  • 450
  • 454

  • Properties
    C15H10O5    270.24





    1:  Pecere T, Gazzola MV, Mucignat C, Parolin C, Vecchia FD, Cavaggioni A, Basso G, Diaspro A, Salvato B, Carli M, Palu G.
    Aloe-emodin is a new type of anticancer agent with selective activity against neuroectodermal tumors.
    Cancer Res.    impact factor:   8.614
    2000;  60(11): 2800-4

    2:  Sarno S, Moro S, Meggio F, Zagotto G, Dal Ben D, Ghisellini P, Battistutta R, Zanotti G, Pinna LA.
    Toward the rational design of protein kinase casein kinase-2 inhibitors.
    Pharmacol Ther.    impact factor:   7.711
    2002;  93(2-3): 159-68

    3:  Battistutta R, Sarno S, De Moliner E, Papinutto E, Zanotti G, Pinna LA.
    The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2.
    J Biol Chem.    impact factor:   7.666
    2000;  275(38): 29618-22

    4:  Channavajhala P, Seldin DC.
    Functional interaction of protein kinase CK2 and c-Myc in lymphomagenesis.
    Oncogene.    impact factor:   6.517
    2002;  21(34): 5280-8

    5:  Bhat-Nakshatri P, Sweeney CJ, Nakshatri H.
    Identification of signal transduction pathways involved in constitutive NF-kappaB activation in breast cancer cells.
    Oncogene.    impact factor:   6.517
    2002;  21(13): 2066-78

     
    Time used: 110 milliseconds.

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