ID Name Structure References (top 5) Molecular Target(s)
1ID:2395
N-FORRNYL-N-DEACETYLCOLCHICINE


NSC#:403142

Freqency:
in 2 ingredients:

  • 325
  • 497
  • in 16 recipes:

  • 206
  • 253
  • 271
  • 316
  • 332
  • 344
  • 345
  • 394
  • 399
  • 400
  • 410
  • 421
  • 433
  • 455
  • 466
  • 513

  • Properties
    C21H23NO6    385.41





    1:  Chakrabarti G, Sengupta S, Bhattacharyya B.
    Thermodynamics of colchicinoid-tubulin interactions. Rrol of B-ring and C-7 substituent.
    J Biol Chem.    impact factor:   7.666
    1996;  271(6): 2897-901

    2:  Williams RF, Mumford CL, Williams GA, Floyd LJ, Aivaliotis MJ, Martinez RA, Robinson AK, Barnes LD.
    A photoaffinity derivative of colchicine: 6'-(4'-azido-2'-nitrophenylamino)hexanoyldeacetylcolchicine. Photolabeling and location of the colchicine-binding site on the alpha-subunit of tubulin.
    J Biol Chem.    impact factor:   7.666
    1985;  260(25): 13794-802

    3:  Pyles EA, Hastie SB.
    Effect of the B ring and the C-7 substituent on the kinetics of colchicinoid-tubulin associations.
    Biochemistry.    impact factor:   4.493
    1993;  32(9): 2329-36

    4:  Pyles EA, Rava RP, Hastie SB.
    Effect of B-ring substituents on absorption and circular dichroic spectra of colchicine analogues.
    Biochemistry.    impact factor:   4.493
    1992;  31(7): 2034-9

    5:  Floyd LJ, Barnes LD, Williams RF.
    Photoaffinity labeling of tubulin with (2-nitro-4-azidophenyl)deacetylcolchicine: direct evidence for two colchicine binding sites.
    Biochemistry.    impact factor:   4.493
    1989;  28(21): 8515-25

     
    Time used: 141 milliseconds.

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