ID Name Structure References (top 5) Molecular Target(s)
1ID:320
ANDROGRAPHOLIDE


NSC#:383468
Aldrich#:10200
Aldrich#:365645

Freqency:
in 1 ingredients:

  • 202
  • in 3 recipes:

  • 5
  • 209
  • 264

  • Properties
    C20H30O5    350.45





    1:  Basak A, Zhong M, Munzer JS, Chretien M, Seidah NG.
    Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides.
    Biochem J.    impact factor:   4.349
    2001;  353(Pt 3): 537-45

    2:  Basak A, Cooper S, Roberge AG, Banik UK, Chretien M, Seidah NG.
    Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters.
    Biochem J.    impact factor:   4.349
    1999;  338 ( Pt 1): 107-13

    3:  Shen YC, Chen CF, Chiou WF.
    Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism(s) involved in its anti-inflammatory effect.
    Br J Pharmacol.    impact factor:   3.722
    2002;  135(2): 399-406

    4:  Chiou WF, Chen CF, Lin JJ.
    Mechanisms of suppression of inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells by andrographolide.
    Br J Pharmacol.    impact factor:   3.722
    2000;  129(8): 1553-60

    5:  Chiou WF, Lin JJ, Chen CF.
    Andrographolide suppresses the expression of inducible nitric oxide synthase in macrophage and restores the vasoconstriction in rat aorta treated with lipopolysaccharide.
    Br J Pharmacol.    impact factor:   3.722
    1998;  125(2): 327-34

    LC
    MET
    P450
    ROS
    STEP
    PKC
     
    Time used: 157 milliseconds.

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