ID Name Structure References (top 5) Molecular Target(s)
1ID:3562
ISOPIMPINELLIN


NSC#:217988
NSC#:401288

Freqency:
in 2 ingredients:

  • 733
  • 881
  • in 10 recipes:

  • 37
  • 83
  • 268
  • 291
  • 339
  • 342
  • 345
  • 352
  • 359
  • 438

  • Properties
    C13H10O5    246.22





    1:  Kleiner HE, Vulimiri SV, Starost MF, Reed MJ, DiGiovanni J.
    Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene in SENCAR mice.
    Carcinogenesis.    impact factor:   4.118
    2002;  23(10): 1667-75

    2:  Kleiner HE, Vulimiri SV, Miller L, Johnson WH Jr, Whitman CP, DiGiovanni J.
    Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of SENCAR mice.
    Carcinogenesis.    impact factor:   4.118
    2001;  22(1): 73-82

    3:  Cai Y, Kleiner H, Johnston D, Dubowski A, Bostic S, Ivie W, DiGiovanni J.
    Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice.
    Carcinogenesis.    impact factor:   4.118
    1997;  18(8): 1521-7

    4:  Kleiner HE, Vulimiri SV, Reed MJ, Uberecken A, DiGiovanni J.
    Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation.
    Chem Res Toxicol.    impact factor:   3.47
    2002;  15(2): 226-35

    5:  Cai Y, Bennett D, Nair RV, Ceska O, Ashwood-Smith MJ, DiGiovanni J.
    Inhibition and inactivation of murine hepatic ethoxy- and pentoxyresorufin O-dealkylase by naturally occurring coumarins.
    Chem Res Toxicol.    impact factor:   3.47
    1993;  6(6): 872-9

     
    Time used: 125 milliseconds.

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