ID Name Structure References (top 5) Molecular Target(s)
1ID:3883
LIGUSTILIDE

Freqency:
in 2 ingredients:

  • 376
  • 857
  • in 88 recipes:

  • 41
  • 44
  • 48
  • 55
  • 72
  • 80
  • 85
  • 87
  • 95
  • 96
  • 102
  • 106
  • 107
  • 109
  • 110
  • 111
  • 123
  • 126
  • 130
  • 150
  • 155
  • 156
  • 157
  • 161
  • 170
  • 181
  • 189
  • 193
  • 198
  • 229
  • 230
  • 232
  • 244
  • 272
  • 275
  • 279
  • 280
  • 287
  • 289
  • 290
  • 292
  • 297
  • 303
  • 308
  • 322
  • 324
  • 338
  • 340
  • 342
  • 343
  • 346
  • 347
  • 351
  • 361
  • 362
  • 363
  • 367
  • 375
  • 376
  • 382
  • 388
  • 399
  • 400
  • 402
  • 403
  • 405
  • 409
  • 434
  • 438
  • 441
  • 443
  • 444
  • 446
  • 448
  • 456
  • 458
  • 459
  • 472
  • 473
  • 482
  • 494
  • 507
  • 510
  • 514
  • 515
  • 516
  • 521
  • 527

  • Properties
    C12H14O2    190.24





    1:  Matsumoto K, Kohno S, Ojima K, Tezuka Y, Kadota S, Watanabe H.
    Effects of methylenechloride-soluble fraction of Japanese angelica root extract, ligustilide and butylidenephthalide, on pentobarbital sleep in group-housed and socially isolated mice.
    Life Sci.    impact factor:   1.774
    1998;  62(23): 2073-82

    2:  Beck JJ, Stermitz FR.
    Addition of methyl thioglycolate and benzylamine to (Z)-ligustilide, a bioactive unsaturated lactone constituent of several herbal medicines. An improved synthesis of (Z)-ligustilide.
    J Nat Prod.    impact factor:   1.652
    1995;  58(7): 1047-55

    3:  Kobayashi S, Mimura Y, Naitoh T, Kimura I, Kimura M.
    Chemical structure-activity of cnidium rhizome-derived phthalides for the competence inhibition of proliferation in primary cultures of mouse aorta smooth muscle cells.
    Jpn J Pharmacol.    impact factor:   1.317
    1993;  63(3): 353-9

    4:  Kobayashi S, Mimura Y, Notoya K, Kimura I, Kimura M.
    Antiproliferative effects of the traditional Chinese medicine shimotsu-to, its component cnidium rhizome and derived compounds on primary cultures of mouse aorta smooth muscle cells.
    Jpn J Pharmacol.    impact factor:   1.317
    1992;  60(4): 397-401

    5:  Ko WC.
    A newly isolated antispasmodic--butylidenephthalide.
    Jpn J Pharmacol.    impact factor:   1.317
    1980;  30(1): 85-91

     
    Time used: 484 milliseconds.

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