ID Name Structure References (top 5) Molecular Target(s)
1ID:5661
SAIKOSAPONIN A

Freqency:
in 1 ingredients:

  • 213
  • in 18 recipes:

  • 41
  • 49
  • 84
  • 96
  • 107
  • 123
  • 169
  • 279
  • 280
  • 286
  • 287
  • 292
  • 346
  • 354
  • 405
  • 449
  • 519
  • 523

  • Properties
    C42H68O13    780.99





    1:  Yano H, Mizoguchi A, Fukuda K, Haramaki M, Ogasawara S, Momosaki S, Kojiro M.
    The herbal medicine sho-saiko-to inhibits proliferation of cancer cell lines by inducing apoptosis and arrest at the G0/G1 phase.
    Cancer Res.    impact factor:   8.614
    1994;  54(2): 448-54

    2:  Hsu MJ, Cheng JS, Huang HC.
    Effect of saikosaponin, a triterpene saponin, on apoptosis in lymphocytes: association with c-myc, p53, and bcl-2 mRNA.
    Br J Pharmacol.    impact factor:   3.722
    2000;  131(7): 1285-93

    3:  Wu WS, Hsu HY.
    Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells.
    Biochem Biophys Res Commun.    impact factor:   3.161
    2001;  285(2): 183-7

    4:  Zong Z, Fujikawa-Yamamoto K, Tanino M, Teraoka K, Yamagishi H, Odashima S.
    Saikosaponin b2-induced apoptosis of cultured B16 melanoma cell line through down-regulation of PKC activity.
    Biochem Biophys Res Commun.    impact factor:   3.161
    1996;  219(2): 480-5

    5:  Kato M, Pu MY, Isobe K, Iwamoto T, Nagase F, Lwin T, Zhang YH, Hattori T, Yanagita N, Nakashima I.
    Characterization of the immunoregulatory action of saikosaponin-d.
    Cell Immunol.    impact factor:   2.252
    1994;  159(1): 15-25

     
    Time used: 78 milliseconds.

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