ID Name Structure References (top 5) Molecular Target(s)
1ID:5729
SAUSSUREA LACTONE

Freqency:
in 1 ingredients:

  • 43
  • in 48 recipes:

  • 19
  • 20
  • 21
  • 22
  • 23
  • 24
  • 29
  • 30
  • 41
  • 43
  • 48
  • 122
  • 123
  • 124
  • 150
  • 169
  • 221
  • 223
  • 229
  • 233
  • 236
  • 241
  • 242
  • 243
  • 247
  • 248
  • 252
  • 258
  • 260
  • 272
  • 274
  • 279
  • 283
  • 288
  • 294
  • 297
  • 311
  • 401
  • 402
  • 403
  • 434
  • 487
  • 490
  • 497
  • 500
  • 505
  • 513
  • 521

  • Properties
    C15H22O2    234.34





    1:  Chen HC, Chou CK, Lee SD, Wang JC, Yeh SF.
    Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells.
    Antiviral Res.    impact factor:   2.758
    1995;  27(1-2): 99-109

    2:  Choi JH, Ha J, Park JH, Lee JY, Lee YS, Park HJ, Choi JW, Masuda Y, Nakaya K, Lee KT.
    Costunolide triggers apoptosis in human leukemia U937 cells by depleting intracellular thiols.
    Jpn J Cancer Res.    impact factor:   2.12
    2002;  93(12): 1327-33

    3:  Cho JY, Baik KU, Jung JH, Park MH.
    In vitro anti-inflammatory effects of cynaropicrin, a sesquiterpene lactone, from Saussurea lappa.
    Eur J Pharmacol.    impact factor:   2.047
    2000;  398(3): 399-407

    4:  Cheminat A, Stampf JL, Benezra C, Farrall MJ, Frechet JM.
    Allergic contact dermatitis to costus: removal of haptens with polymers.
    Acta Derm Venereol.    impact factor:   1.549
    1981;  61(6): 525-9

    5:  Jeong SJ, Itokawa T, Shibuya M, Kuwano M, Ono M, Higuchi R, Miyamoto T.
    Costunolide, a sesquiterpene lactone from Saussurea lappa, inhibits the VEGFR KDR/Flk-1 signaling pathway.
    Cancer Lett.    impact factor:   1.518
    2002;  187(1-2): 129-33

     
    Time used: 94 milliseconds.

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