ID Name Structure References (top 5) Molecular Target(s)
1ID:5767
SCOPARONE


Aldrich#:254886

Freqency:
in 1 ingredients:

  • 184
  • in 14 recipes:

  • 47
  • 49
  • 278
  • 279
  • 280
  • 287
  • 288
  • 291
  • 294
  • 297
  • 340
  • 519
  • 523
  • 527

  • Properties
    C11H10O4    206.2





    1:  Baader M, Gnerre C, Stegeman JJ, Meyer UA.
    Transcriptional activation of cytochrome P450 CYP2C45 by drugs is mediated by the chicken xenobiotic receptor (CXR) interacting with a phenobarbital response enhancer unit.
    J Biol Chem.    impact factor:   7.666
    2002;  277(18): 15647-53

    2:  Huang HC, Weng YI, Lee CR, Jan TR, Chen YL, Lee YT.
    Protection by scoparone against the alterations of plasma lipoproteins, vascular morphology and vascular reactivity in hyperlipidaemic diabetic rabbit.
    Br J Pharmacol.    impact factor:   3.722
    1993;  110(4): 1508-14

    3:  Legrum W, Kling L, Funke E.
    Radioisomers of scoparone (6,7-dimethoxycoumarin) as a tool for in vivo differentiation of various hepatic monooxygenase inducers in mice using the breath test technique.
    J Pharmacol Exp Ther.    impact factor:   3.3
    1984;  228(3): 769-73

    4:  Meyer RP, Hagemeyer CE, Knoth R, Kurz G, Volk B.
    Oxidative hydrolysis of scoparone by cytochrome p450 CYP2C29 reveals a novel metabolite.
    Biochem Biophys Res Commun.    impact factor:   3.161
    2001;  285(1): 32-9

    5:  Chen YL, Huang HC, Weng YI, Yu YJ, Lee YT.
    Morphological evidence for the antiatherogenic effect of scoparone in hyperlipidaemic diabetic rabbits.
    Cardiovasc Res.    impact factor:   3.092
    1994;  28(11): 1679-85

     
    Time used: 94 milliseconds.

    Webpage designed by Dr. Xueliang Fang, last updated on 3/10/2005