ID Name Structure References (top 5) Molecular Target(s)
1ID:5820
SENNOSIDE A


NSC#:112929(<1uM)
NSC#:112930

Freqency:
in 2 ingredients:

  • 14
  • 143
  • in 35 recipes:

  • 4
  • 6
  • 43
  • 98
  • 114
  • 138
  • 145
  • 150
  • 152
  • 154
  • 165
  • 166
  • 196
  • 206
  • 208
  • 210
  • 219
  • 226
  • 228
  • 231
  • 274
  • 289
  • 320
  • 362
  • 364
  • 378
  • 415
  • 428
  • 434
  • 445
  • 464
  • 465
  • 519
  • 521
  • 527

  • Properties
    C42H38O20    862.74





    1:  Staumont G, Fioramonti J, Frexinos J, Bueno L.
    Changes in colonic motility induced by sennosides in dogs: evidence of a prostaglandin mediation.
    Gut.    impact factor:   5.748
    1988;  29(9): 1180-7

    2:  Stephen AM, Wiggins HS, Cummings JH.
    Effect of changing transit time on colonic microbial metabolism in man.
    Gut.    impact factor:   5.748
    1987;  28(5): 601-9

    3:  Marcus SN, Heaton KW.
    Irritable bowel-type symptoms in spontaneous and induced constipation.
    Gut.    impact factor:   5.748
    1987;  28(2): 156-9

    4:  Kiernan JA, Heinicke EA.
    Sennosides do not kill myenteric neurons in the colon of the rat or mouse.
    Neuroscience.    impact factor:   3.924
    1989;  30(3): 837-42

    5:  van Gorkom BA, Karrenbeld A, van der Sluis T, Zwart N, de Vries EG, Kleibeuker JH.
    Apoptosis induction by sennoside laxatives in man; escape from a protective mechanism during chronic sennoside use?
    J Pathol.    impact factor:   3.833
    2001;  194(4): 493-9

     
    Time used: 125 milliseconds.

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