ID Name Structure References (top 5) Molecular Target(s)
1ID:617
BERBERINE


NSC#:150446
NSC#:163088

Freqency:
in 11 ingredients:

  • 2
  • 10
  • 29
  • 97
  • 234
  • 235
  • 342
  • 380
  • 421
  • 451
  • 609
  • in 45 recipes:

  • 2
  • 3
  • 6
  • 8
  • 25
  • 36
  • 48
  • 79
  • 104
  • 126
  • 127
  • 135
  • 140
  • 145
  • 149
  • 150
  • 153
  • 166
  • 205
  • 206
  • 210
  • 212
  • 219
  • 221
  • 226
  • 228
  • 237
  • 244
  • 259
  • 267
  • 271
  • 286
  • 325
  • 335
  • 351
  • 352
  • 355
  • 362
  • 421
  • 438
  • 465
  • 485
  • 500
  • 502
  • 521

  • Properties
    C20H18NO4    336.37





    1:  Schumacher MA, Miller MC, Grkovic S, Brown MH, Skurray RA, Brennan RG.
    Structural mechanisms of QacR induction and multidrug recognition.
    Science.    impact factor:   24.595
    2001;  294(5549): 2158-63

    2:  Jin GZ, Zhu ZT, Fu Y.
    (-)-Stepholidine: a potential novel antipsychotic drug with dual D1 receptor agonist and D2 receptor antagonist actions.
    Trends Pharmacol Sci.    impact factor:   11.697
    2002;  23(1): 4-7

    3:  Jang MJ, Jwa M, Kim JH, Song K.
    Selective inhibition of MAPKK Wis1 in the stress-activated MAPK cascade of Schizosaccharomyces pombe by novel berberine derivatives.
    J Biol Chem.    impact factor:   7.666
    2002;  277(14): 12388-95

    4:  Li L, He Z, Pandey GK, Tsuchiya T, Luan S.
    Functional cloning and characterization of a plant efflux carrier for multidrug and heavy metal detoxification.
    J Biol Chem.    impact factor:   7.666
    2002;  277(7): 5360-8

    5:  Polak M, Hud NV.
    Complete disproportionation of duplex poly(dT)*poly(dA) into triplex poly(dT)*poly(dA)*poly(dT) and poly(dA) by coralyne.
    Nucleic Acids Res.    impact factor:   5.748
    2002;  30(4): 983-92

    ARG
    BCL-2
    C-AMP
    CB-1
    CD-45
    DDR
    HGF
    KIT
    LC
    MET
    MRP
    MDR1
    MRP
    P38
    P53
    P450
    SAP
    STEP
    TOPOISOMERASE II ALPHA
    YES
    PKC
     
    Time used: 328 milliseconds.

    Webpage designed by Dr. Xueliang Fang, last updated on 3/10/2005