ID Name Structure References (top 5) Molecular Target(s)
1ID:6973
ARCTIGENIN


NSC#:24871
NSC#:659370

Freqency:
in 2 ingredients:

  • 348
  • 669
  • in 28 recipes:

  • 58
  • 72
  • 74
  • 91
  • 108
  • 114
  • 121
  • 139
  • 152
  • 167
  • 226
  • 230
  • 306
  • 313
  • 315
  • 322
  • 324
  • 327
  • 343
  • 359
  • 360
  • 371
  • 391
  • 398
  • 418
  • 436
  • 459
  • 466

  • Properties
    C21H24O6    372.41





    1:  Eich E, Pertz H, Kaloga M, Schulz J, Fesen MR, Mazumder A, Pommier Y.
    (-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase.
    J Med Chem.    impact factor:   4.079
    1996;  39(1): 86-95

    2:  Sibi MP, Liu P, Ji J, Hajra S, Chen JX.
    Free-radical-mediated conjugate additions. Enantioselective synthesis of butyrolactone natural products: (-)-enterolactone, (-)-arctigenin, (-)-isoarctigenin, (-)-nephrosteranic acid, and (-)-roccellaric acid.
    J Org Chem.    impact factor:   3.44
    2002;  67(6): 1738-45

    3:  Jang YP, Kim SR, Choi YH, Kim J, Kim SG, Markelonis GJ, Oh TH, Kim YC.
    Arctigenin protects cultured cortical neurons from glutamate-induced neurodegeneration by binding to kainate receptor.
    J Neurosci Res.    impact factor:   3.126
    2002;  68(2): 233-40

    4:  Hirano T, Gotoh M, Oka K.
    Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells.
    Life Sci.    impact factor:   1.774
    1994;  55(13): 1061-9

    5:  Hirano T, Homma M, Oka K, Naito T, Hosaka K, Mitsuhashi H.
    Ion-sparing diuresis by 2,3-dibenzylbutane-1,4-diol, a synthetic mammalian-lignan derivative.
    Life Sci.    impact factor:   1.774
    1991;  49(25): 1871-8

     
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