ID Name Structure References (top 5) Molecular Target(s)
1ID:7057
BRUCEANTIN


NSC#:165563(<1uM)

Freqency:
in 1 ingredients:

  • 191
  • in 7 recipes:

  • 15
  • 34
  • 76
  • 185
  • 265
  • 335
  • 341

  • Properties
    C28H36O11    548.58





    1:  Cragg G, Suffness M.
    Metabolism of plant-derived anticancer agents.
    Pharmacol Ther.    impact factor:   7.711
    1988;  37(3): 425-61

    2:  Rodriguez-Fonseca C, Amils R, Garrett RA.
    Fine structure of the peptidyl transferase centre on 23 S-like rRNAs deduced from chemical probing of antibiotic-ribosome complexes.
    J Mol Biol.    impact factor:   5.501
    1995;  247(2): 224-35

    3:  Liao LL, Kupchan SM, Horwitz SB.
    Mode of action of the antitumor compound bruceantin, an inhibitor of protein synthesis.
    Mol Pharmacol.    impact factor:   5.465
    1976;  12(1): 167-76

    4:  Wright CW, O'Neill MJ, Phillipson JD, Warhurst DC.
    Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids.
    Antimicrob Agents Chemother.    impact factor:   3.969
    1988;  32(11): 1725-9

    5:  O'Neill MJ, Bray DH, Boardman P, Phillipson JD, Warhurst DC, Peters W, Suffness M.
    Plants as sources of antimalarial drugs: in vitro antimalarial activities of some quassinoids.
    Antimicrob Agents Chemother.    impact factor:   3.969
    1986;  30(1): 101-4

     
    Time used: 109 milliseconds.

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