ID Name Structure References (top 5) Molecular Target(s)
1ID:8127
BETULINIC ACID


NSC#:113090
NSC#:677578
Aldrich#:855057

Freqency:
in 4 ingredients:

  • 13
  • 669
  • 723
  • 856
  • in 50 recipes:

  • 20
  • 21
  • 26
  • 58
  • 72
  • 74
  • 77
  • 78
  • 91
  • 101
  • 108
  • 114
  • 121
  • 139
  • 146
  • 152
  • 158
  • 167
  • 226
  • 230
  • 232
  • 241
  • 245
  • 276
  • 288
  • 291
  • 306
  • 311
  • 312
  • 315
  • 322
  • 324
  • 327
  • 332
  • 343
  • 359
  • 360
  • 363
  • 371
  • 381
  • 391
  • 398
  • 413
  • 418
  • 430
  • 436
  • 452
  • 459
  • 466
  • 490

  • Properties
    C30H48O3    456.7





    1:  Costantini P, Jacotot E, Decaudin D, Kroemer G.
    Mitochondrion as a novel target of anticancer chemotherapy.
    J Natl Cancer Inst.    impact factor:   12.945
    2000;  92(13): 1042-53

    2:  Fulda S, Susin SA, Kroemer G, Debatin KM.
    Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells.
    Cancer Res.    impact factor:   8.614
    1998;  58(19): 4453-60

    3:  Rieber M, Rieber MS.
    Correspondence re: S. Fulda et al., Betulinic acid triggers CD95 (Apo1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors. Cancer Res., 57: 4956-4964, 1997.
    Cancer Res.    impact factor:   8.614
    1998;  58(24): 5876-7

    4:  Fulda S, Friesen C, Los M, Scaffidi C, Mier W, Benedict M, Nunez G, Krammer PH, Peter ME, Debatin KM.
    Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors.
    Cancer Res.    impact factor:   8.614
    1997;  57(21): 4956-64

    5:  Fulda S, Scaffidi C, Susin SA, Krammer PH, Kroemer G, Peter ME, Debatin KM.
    Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid.
    J Biol Chem.    impact factor:   7.666
    1998;  273(51): 33942-8

     
    Time used: 625 milliseconds.

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