ID Name Structure References (top 5) Molecular Target(s)
1ID:83
ACETYLSHIKONIN


NSC#:110199
NSC#:291844

Freqency:
in 1 ingredients:

  • 266
  • in 39 recipes:

  • 3
  • 19
  • 41
  • 52
  • 71
  • 73
  • 74
  • 86
  • 91
  • 93
  • 115
  • 118
  • 141
  • 151
  • 152
  • 154
  • 159
  • 167
  • 186
  • 202
  • 235
  • 253
  • 280
  • 283
  • 289
  • 335
  • 341
  • 373
  • 395
  • 417
  • 439
  • 440
  • 443
  • 455
  • 466
  • 478
  • 491
  • 517
  • 519

  • Properties
    C18H18O6    330.33





    1:  Ahn BZ, Baik KU, Kweon GR, Lim K, Hwang BD.
    Acylshikonin analogues: synthesis and inhibition of DNA topoisomerase-I.
    J Med Chem.    impact factor:   4.079
    1995;  38(6): 1044-7

    2:  Wang JP, Tsao LT, Raung SL, Hsu MF, Kuo SC.
    Investigation of the inhibition by acetylshikonin of the respiratory burst in rat neutrophils.
    Br J Pharmacol.    impact factor:   3.722
    1997;  121(3): 409-16

    3:  Yamamoto H, Inoue K, Li SM, Heide L.
    Geranylhydroquinone 3"-hydroxylase, a cytochrome P-450 monooxygenase from Lithospermum erythrorhizon cell suspension cultures.
    Planta.    impact factor:   2.977
    2000;  210(2): 312-7

    4:  Wang JP, Kuo SC.
    Impairment of phosphatidylinositol signaling in acetylshikonin-treated neutrophils.
    Biochem Pharmacol.    impact factor:   2.755
    1997;  53(8): 1173-7

    5:  Ko FN, Lee YS, Kuo SC, Chang YS, Teng CM.
    Inhibition on platelet activation by shikonin derivatives isolated from Arnebia euchroma.
    Biochim Biophys Acta.    impact factor:   2.59
    1995;  1268(3): 329-34

    C-AMP
    CB-1
    P450
    PKC
     
    Time used: 140 milliseconds.

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