ID Name Structure References (top 5) Molecular Target(s)
1ID:91
ACONITINE


NSC#:56464
Aldrich#:A229
Aldrich#:R426105

Freqency:
in 4 ingredients:

  • 326
  • 399
  • 432
  • 485
  • in 8 recipes:

  • 17
  • 76
  • 146
  • 184
  • 185
  • 222
  • 285
  • 478

  • Properties
    C34H47NO11    645.74





    1:  Hatton GI, Yang QZ.
    Synaptic potentials mediated by alpha 7 nicotinic acetylcholine receptors in supraoptic nucleus.
    J Neurosci.    impact factor:   8.955
    2002;  22(1): 29-37

    2:  Buisson B, Bertrand D.
    Chronic exposure to nicotine upregulates the human (alpha)4((beta)2 nicotinic acetylcholine receptor function.
    J Neurosci.    impact factor:   8.955
    2001;  21(6): 1819-29

    3:  Liu Y, Ford B, Mann MA, Fischbach GD.
    Neuregulins increase alpha7 nicotinic acetylcholine receptors and enhance excitatory synaptic transmission in GABAergic interneurons of the hippocampus.
    J Neurosci.    impact factor:   8.955
    2001;  21(15): 5660-9

    4:  Alkondon M, Pereira EF, Eisenberg HM, Albuquerque EX.
    Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for inhibition and disinhibition of neuronal networks.
    J Neurosci.    impact factor:   8.955
    2000;  20(1): 66-75

    5:  Si ML, Lee TJ.
    Alpha7-nicotinic acetylcholine receptors on cerebral perivascular sympathetic nerves mediate choline-induced nitrergic neurogenic vasodilation.
    Circ Res.    impact factor:   8.281
    2002;  91(1): 62-9

    ARG
    C-AMP
    CB-1
    DDR
    ERK
    KDR
    LC
    P450
    STEP
    TRKA
    PKC
     
    Time used: 672 milliseconds.

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