Ingredient ID 118 
Chinese Pronunciation JUEMINGZI 
English Name Cassia Seed  
Latin Name Semen Cassiae  
Aliases CaoJueMing
Cancers Cervical  
Identified Compounds

order by name

1. Chrysophanol

   C15H10O4   254.24

2. Chrysophanic Acid Anthrone

   C15H12O3   240.26

3. Chrysophanol-1-beta-gentiobioside

   C16H12O4   268.27

4. Emodin

   C15H10O5   270.24
NSC# 408120 Activity (<10uM)

5. Torachrysone

   C14H14O4   246.26

6. Toralactone

   C15H12O5   272.25

Recipes that contain
  1. 103      RuAiFangEr
  2. 383      RuAiFang

Available references (order by impact factor):

1:  Tewari JP, Dixit BB, Mishra SS.
Fractionation of fatty acids of Cassia tora seed oil with urea.
J Pharm Sci.    impact factor:   2.27
1965;  54(6): 923

2:  O'Hara PJ, Pierce KR.
A toxic cardiomyopathy caused by Cassia occidentalis. II. Biochemical studies in poisoned rabbits.
Vet Pathol.    impact factor:   1.682
1974;  11(2): 110-24

3:  O'Hara PJ, Pierce KR.
A toxic cardiomyopathy caused by Cassia occidentalis. I. Morphologic studies in poisoned rabbits.
Vet Pathol.    impact factor:   1.682
1974;  11(2): 97-109

4:  Kuo YH, Lee PH, Wein YS.
Four new compounds from the seeds of Cassia fistula.
J Nat Prod.    impact factor:   1.652
2002;  65(8): 1165-7

5:  Yun-Choi HS, Kim JH, Takido M.
Potential inhibitors of platelet aggregation from plant sources, V. Anthraquinones from seeds of Cassia obtusifolia and related compounds.
J Nat Prod.    impact factor:   1.652
1990;  53(3): 630-3

6:  Chaubey M, Kapoor VP.
Structure of a galactomannan from the seeds of Cassia angustifolia Vahl.
Carbohydr Res.    impact factor:   1.606
2001;  332(4): 439-44

7:  Kapoor VP, Taravel FR, Joseleau JP, Milas M, Chanzy H, Rinaudo M.
Cassia spectabilis DC seed galactomannan: structural, crystallographical and rheological studies.
Carbohydr Res.    impact factor:   1.606
1998;  306(1-2): 231-41

8:  Kumar P, Singh V, Mishra UC, Gupta PC.
A water-soluble polysaccharide isolated from seeds of Cassia ovata.
Carbohydr Res.    impact factor:   1.606
1990;  198(2): 384-6

9:  Seth RP, Mukherjee S, Verma SD.
Investigations on partial structure of galactomannan "A" from Cassia renigera seed.
Carbohydr Res.    impact factor:   1.606
1984;  125(2): 336-9

10:  Ross TT, Hayes CE, Goldstein IJ.
Carbohydrate-binding properties of an immobilized alpha-D-galactopyranosyl-binding protein (lectin) from the seeds of Bandeiraea simplicifolia.
Carbohydr Res.    impact factor:   1.606
1976;  47(1): 91-7

11:  Kim HL, Camp BJ, Grigsby RD.
Isolation of N-methylmorpholine from the seeds of Cassia occidentalis L. (coffee senna).
J Agric Food Chem.    impact factor:   1.56
1971;  19(1): 198-9

12:  Andrade CT, Azero EG, Luciano L, Goncalves MP.
Solution properties of the galactomannans extracted from the seeds of Caesalpinia pulcherrima and Cassia javanica: comparison with locust bean gum.
Int J Biol Macromol.    impact factor:   1.514
1999;  26(2-3): 181-5

13:  Wong SM, Wong MM, Seligmann O, Wagner H.
New antihepatotoxic naphtho-pyrone glycosides from the seeds of Cassia tora.
Planta Med.    impact factor:   1.438
1989;  55(3): 276-80

14:  Tiwari RD, Richards A.
Anthraquinone pigments from seeds of Cassia renigera.
Planta Med.    impact factor:   1.438
1979;  36(1): 91-4

15:  Lal J, Gupta PC.
Galactomannan from the seeds of Cassia fistula.
Planta Med.    impact factor:   1.438
1972;  22(1): 70-7

16:  Rizvi SA, Gupta PC, Kaul RK.
The structure of a galactomannan from the seeds of Cassia nodosa.
Planta Med.    impact factor:   1.438
1971;  20(1): 24-32

17:  Rizvi SA, Gupta PC, Srivastava KC, Kaul RK.
Chemical examination of the fixed oil from the seeds of Cassia nodosa.
Planta Med.    impact factor:   1.438
1968;  16(3): 317-22

18:  Voss KA, Brennecke LH.
Toxicological and hematological effects of sicklepod (Cassia obtusifolia) seeds in Sprague-Dawley rats: a subchronic feeding study.
Toxicon.    impact factor:   1.248
1991;  29(11): 1329-36

19:  Shah SA, Ravishankara MN, Nirmal A, Shishoo CJ, Rathod IS, Suhagia BN.
Estimation of individual sennosides in plant materials and marketed formulations by an HPTLC method.
J Pharm Pharmacol.    impact factor:   1.195
2000;  52(4): 445-9

20:  Hatano T, Uebayashi H, Ito H, Shiota S, Tsuchiya T, Yoshida T.
Phenolic constituents of Cassia seeds and antibacterial effect of some naphthalenes and anthraquinones on methicillin-resistant Staphylococcus aureus.
Chem Pharm Bull (Tokyo).    impact factor:   1.117
1999;  47(8): 1121-7

21:  Kitanaka S, Nakayama T, Shibano T, Ohkoshi E, Takido M.
Antiallergic agent from natural sources. Structures and inhibitory effect of histamine release of naphthopyrone glycosides from seeds of Cassia obtusifolia L.
Chem Pharm Bull (Tokyo).    impact factor:   1.117
1998;  46(10): 1650-2

22:  Nikaido T, Ohmoto T, Sankawa U, Kitanaka S, Takido M.
Inhibitors of adenosine 3',5'-cyclic monophosphate phosphodiesterase in Cassia seed.
Chem Pharm Bull (Tokyo).    impact factor:   1.117
1984;  32(8): 3075-8

23:  Flunker LK, Damron BL, Sundlof SF.
Response of White Leghorn hens to various dietary levels of Cassia obtusifolia and nutrient fortification as a means of alleviating depressed performance.
Poult Sci.    impact factor:   1.107
1989;  68(7): 909-13

24:  Gupta D, Singh J.
Flavonoid glycosides from Cassia alata.
Phytochemistry.    impact factor:   1.106
1991;  30(8): 2761-3

25:  Calore EE, Cavaliere MJ, Haraguchi M, Gorniak SL, Dagli ML, Raspantini PC, Calore NM, Weg R.
Toxic peripheral neuropathy of chicks fed Senna occidentalis seeds.
Ecotoxicol Environ Saf.    impact factor:   1.06
1998;  39(1): 27-30

26:  Cavaliere MJ, Calore EE, Haraguchi M, Gorniak SL, Dagli ML, Raspantini PC, Calore NM, Weg R.
Mitochondrial myopathy in Senna occidentalis-seed-fed chicken.
Ecotoxicol Environ Saf.    impact factor:   1.06
1997;  37(2): 181-5

27:  Wijaya R, Neumann GM, Condron R, Hughes AB, Polya GM.
Defense proteins from seed of Cassia fistula include a lipid transfer protein homologue and a protease inhibitory plant defensin.
Plant Sci.    impact factor:   1.015
2000;  159(2): 243-255

28:  Page RK, Vezey S, Charles OW, Hollifield T.
Effects on feed consumption and egg production of coffee bean seed (Cassia obtusifolia) fed to White Leghorn hens.
Avian Dis.    impact factor:   .984
1977;  21(1): 90-6

29:  Page RK, Fletcher OJ.
Myopathy of the deep pectoral muscle in broiler breeder hens.
Avian Dis.    impact factor:   .984
1975;  19(4): 814-21

30:  Simpson CF, Damron BL, Harms RH.
Toxic myopathy of chicks fed Cassia occidentalis seeds.
Avian Dis.    impact factor:   .984
1971;  15(2): 284-90

31:  Tasaka AC, Weg R, Calore EE, Sinhorini IL, Dagli ML, Haraguchi M, Gorniak SL.
Toxicity testing of Senna occidentalis seed in rabbits.
Vet Res Commun.    impact factor:   .817
2000;  24(8): 573-82

32:  Haraguchi M, Calore EE, Dagli ML, Cavaliere MJ, Calore NM, Weg R, Raspantini PC, Gorniak SL.
Muscle atrophy induced in broiler chicks by parts of Senna occidentalis seeds.
Vet Res Commun.    impact factor:   .817
1998;  22(4): 265-71

33:  Crawford L, Friedman M.
The effects of low levels of dietary toxic weed seeds (jimson weed, Datura stramonium and sicklepod, Cassia obtusifolia) on the relative size of rat liver and levels and function of cytochrome P-450.
Toxicol Lett.    impact factor:   .773
1990;  54(2-3): 175-81

34:  El-Maraghy SS.
Effect of some spices as preservatives for storage of lentil (Lens esculenta L.) seeds.
Folia Microbiol (Praha).    impact factor:   .752
1995;  40(5): 490-2

35:  Gupta M, Mazumder UK, Rath N, Mukhopadhyay DK.
Antitumor activity of methanolic extract of Cassia fistula L. seed against Ehrlich ascites carcinoma.
J Ethnopharmacol.    impact factor:   .687
2000;  72(1-2): 151-6

36:  Sakamoto S, Kudo H, Kawasaki T, Kuwa K, Kasahara N, Sassa S, Okamoto R.
Effects of a Chinese herbal medicine, keishi-bukuryo-gan, on the gonadal system of rats.
J Ethnopharmacol.    impact factor:   .687
1988;  23(2-3): 151-8

37:  Calore EE, Weg R, Haraguchi M, Calore NM, Cavaliere MJ, Sesso A.
Mitochondrial metabolism impairment in muscle fibres of rats chronically intoxicated with Senna occidentalis seeds.
Exp Toxicol Pathol.    impact factor:   .603
2000;  52(4): 357-63

38:  Sakamoto S, Yoshino H, Shirahata Y, Shimodairo K, Okamoto R.
Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas.
Am J Chin Med.    impact factor:   .583
1992;  20(3-4): 313-7

39:  Koo A, Wang JC, Li KM.
Extraction of hypotensive principles from seeds of Cassia tora.
Am J Chin Med.    impact factor:   .583
1976;  4(3): 245-8

40:  Chan SH, Koo A, Li KM.
The involvement of medullary reticular formation in the hypotensive effect of extracts from seeds of Cassia tora.
Am J Chin Med.    impact factor:   .583
1976;  4(4): 383-89

41:  Koo A, Chan WS, Li KM.
A possible reflex mechanism of hypotensive action of extract from Cassia tora seeds.
Am J Chin Med.    impact factor:   .583
1976;  4(3): 249-55

42:  Omer SA, Ibrahim FH, Khalid SA, Adam SE.
Toxicological interactions of Abrus precatorius and Cassia senna in the diet of Lohmann broiler chicks.
Vet Hum Toxicol.    impact factor:   .531
1992;  34(4): 310-3

43:  Putnam MR, Boosinger T, Spano J, Wright J, Wiggins A, D'Andrea G.
Evaluation of Cassia obtusifolia (sicklepod) seed consumption in Holstein calves.
Vet Hum Toxicol.    impact factor:   .531
1988;  30(4): 316-8

44:  Hebert CD, Flory W.
Determination of the oral toxicity of Cassia obtusifolia seeds in chickens.
Vet Hum Toxicol.    impact factor:   .531
1983;  25(3): 164-6

45:  Osman F, Fiad S.
Lipids of two Cassia species and Datura stramonium seeds.
Nahrung.    impact factor:   .395
1976;  20(5): 483-97

46:  Choi JS, Lee HJ, Kang SS.
Alaternin, cassiaside and rubrofusarin gentiobioside, radical scavenging principles from the seeds of Cassia tora on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical.
Arch Pharm Res.    impact factor:   .382
1994;  17(6): 462-6

47:  Agrawal S, Agarwal SS.
Preliminary observations on leukaemia specific agglutinins from seeds.
Indian J Med Res.    impact factor:   .365
1990;  92: 38-42

48:  Kuzuya M, Sakata H, Kondo S, Noguchi A.
[Mechanochemical solid state reactions of natural products for medicinal use containing hydroxyanthraquinone derivatives]
Yakugaku Zasshi.    impact factor:   .238
1991;  111(11): 665-71

49:  Kimura Y, Takido M, Takahashi S.
[Studies on the constituents of the seeds of Cassia obtusifolia Linne. N. The structure of new glucoside, cassiaside (nor-rubrofusarin-6-beta-D-glucoside]
Yakugaku Zasshi.    impact factor:   .238
1966;  86(11): 1087-9

50:  Yadav R, Jain GC.
Antifertility effect of aqueous extract of seeds of Cassia fistula in female rats.
Adv Contracept.    impact factor:   .206
1999;  15(4): 293-301

51:  Vadivel V, Janardhanan K.
Agrobotanical traits and chemical composition of Cassia obtusifolia L.: a lesser-known legume of the Western Ghats region of South India.
Plant Foods Hum Nutr.    impact factor:   .133
2002;  57(2): 151-64

52:  Vadivel V, Janardhanan K.
Chemical composition of the underutilized legume Cassia hirsuta L.
Plant Foods Hum Nutr.    impact factor:   .133
2000;  55(4): 369-81

53:  Barthakur NN, Arnold NP, Alli I.
The Indian laburnum (Cassia fistula L.) fruit: an analysis of its chemical constituents.
Plant Foods Hum Nutr.    impact factor:   .133
1995;  47(1): 55-62

54:  Mungai DN, Coulson CL, Stigter CJ, Ng'ang'a JK, Mugendi DN.
Phenotypic nutrient up-take differences in an alley cropping system in semi-arid Machakos, Kenya.
J Environ Sci (China).    impact factor:   0
2001;  13(2): 164-9

55:  Galloway LF, Fenster CB.
Nuclear and cytoplasmic contributions to intraspecific divergence in an annual legume.
Evolution Int J Org Evolution.    impact factor:   0
2001;  55(3): 488-97

56:  Galloway LF, Fenster CB.
Population differentiation in an annual legume: local adaptation.
Evolution Int J Org Evolution.    impact factor:   0
2000;  54(4): 1173-81

57:  Li X, Liu F.
[Influence of decocting time on the amount of anthraguinone diffused from cassia seeds]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1999;  24(3): 150-1, 190-1

58:  Cao A, Sha M, Meng S, Jiang L, Zhang Z.
[Determination of chrysophanol in semen Cassiae by HPLC]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1997;  22(2): 107-8, 128, inside back cover

59:  Zhang Q, Zhou Z, Yin J, Xiong Y, Wang Y, Sun J.
[Influence of temperature on the chemical constituents and pharmacological effects of semen Cassiae]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1996;  21(11): 663-5, 703

60:  Zhang Q, Yin J, Zhang Y, Zhang J.
[Quality control of semen Cassiae]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1996;  21(11): 646-8, 702

61:  Zhou Z, Ren DQ, Peng WQ, Xia GL.
[Introduction and cultivation of Cinnamomum cassia Presl]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1994;  19(11): 655-60, 701-2

62:  Flory W, Spainhour CB Jr, Colvin B, Herbert CD.
The toxicologic investigation of a feed grain contaminated with seeds of the plant species Cassia.
J Vet Diagn Invest.    impact factor:   0
1992;  4(1): 65-9

63:  Lovisolo O, Kitajima EW.
Nomenclature and relationships of some Brazilian leguminous potyviruses related to bean common mosaic and/or passionfruit woodiness viruses.
Arch Virol Suppl.    impact factor:   0
1992;  5: 307-10

64:  de Mucciarelli SI, de Arellano MA, Cid JA, de Pedernera MM.
[Obtention of protein concentrate from Cassia aphylla seeds. Studies of supplementation]
Acta Cient Venez.    impact factor:   0
1985;  36(5-6): 401-3

65:  Tabata M, Hiraoka N, Ikenoue M, Sano Y, Konoshima M.
The production of antraquinones in callus cultures of Cassia tora.
Lloydia.    impact factor:   0
1975;  38(2): 131-4

66:  Acharya TK, Chatterjee IB.
Isolation of chrysophanic acid-9-anthrone, the major antifungal principle of Cassia tora.
Lloydia.    impact factor:   0
1975;  38(3): 218-20

67:  Debelmas AM, Bezanger-Beauquesne L, Trajman G, Jessenne MG.
[Cassia absus L.grains, new source of polyosides]
Ann Pharm Fr.    impact factor:   0
1974;  32(5): 265-71

68:  Cheema MA, Priddle OD.
Pharmacological investigations of isochaksine, an alkaloid isolated from the seeds of Cassia absus Linn. (Chaksu).
Arch Int Pharmacodyn Ther.    impact factor:   0
1965;  158(2): 307-13


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