Ingredient ID 152 
Chinese Pronunciation KUSHEN 
English Name Lightyellow Sophora Root  
Latin Name Radix Sophorae Flavescentis  
Aliases YeHuaiGen
Cancers Lung
Identified Compounds

order by ID

1. Anagyrine

   C16H22N2O   258.36

2. Baptifoline

   C15H20N2O2   260.34

3. Cytisine

   C11H14N2O   190.24

4. Formononetin

   C16H12O3   252.26

5. Isomatrine

   C15H24N2O   248.37

6. Kuraridin

   C26H30O6   438.52

7. Kuraridinol

   C26H32O7   456.53

8. Kurarinol

   C26H30O7   454.52

9. Matrine

   C15H24N2O   248.37

10. N-methylcytisine

   C12H16N2O   204.27

11. Norkurarinone

   C25H28O6   424.49

12. Oxymatrine

   C15H24N2O2   264.37

13. Sophocarpine

   C15H22N2O   246.35

14. Sophoranol

   C15H24N2O2   264.37

15. Sophoridine

   C15H24N2O   248.37

Recipes that contain
  1. 19      LiQiJiangNiTang
  2. 36      ShanJiaKuShenTang
  3. 51      ErShenErDongTang
  4. 91      ErGenTang
  5. 195      SaiXianAiFang
  6. 223      LiQiJiangNiTang
  7. 239      ErShenTang
  8. 267      ShanJiaKuShenTang
  9. 291      YiQiZiYinTang
  10. 299      ErShenErDongTang
  11. 339      HeiBeiGao
  12. 339      HeiBeiGao
  13. 344      ZhengAiPian
  14. 344      ZhengAiPian
  15. 348      TengLingTang
  16. 371      ErGenTang
  17. 411      PangGuangAiFang
  18. 518      GanAiFangV
  19. 524      GanAiCanKaoFangV

Available references (order by impact factor):

1:  Borges LF, Sidman RL.
Axonal transport of lectins in the peripheral nervous system.
J Neurosci.    impact factor:   8.955
1982;  2(5): 647-53

2:  Yang F, Quan J, Zhang T, Ito Y.
Preparative separation of alkaloids from the root of Sophora flavescens Ait by pH-zone-refining counter-current chromatography.
J Chromatogr A.    impact factor:   2.52
1998;  822(2): 316-20

3:  Kang TH, Jeong SJ, Ko WG, Kim NY, Lee BH, Inagaki M, Miyamoto T, Higuchi R, Kim YC.
Cytotoxic lavandulyl flavanones from Sophora flavescens.
J Nat Prod.    impact factor:   1.652
2000;  63(5): 680-1

4:  Woo ER, Kwak JH, Kim HJ, Park H.
A new prenylated flavonol from the roots of Sophora flavescens.
J Nat Prod.    impact factor:   1.652
1998;  61(12): 1552-4

5:  Iinuma M, Tsuchiya H, Sato M, Yokoyama J, Ohyama M, Ohkawa Y, Tanaka T, Fujiwara S, Fujii T.
Flavanones with potent antibacterial activity against methicillin-resistant Staphylococcus aureus.
J Pharm Pharmacol.    impact factor:   1.195
1994;  46(11): 892-5

6:  Sato M, Tsuchiya H, Miyazaki T, Ohyama M, Tanaka T, Iinuma M.
Antibacterial activity of flavanostilbenes against methicillin-resistant Staphylococcus aureus.
Lett Appl Microbiol.    impact factor:   1.157
1995;  21(4): 219-22

7:  Ko WG, Kang TH, Kim NY, Lee SJ, Kim YC, Ko GI, Ryu SY, Lee BH.
Lavandulylflavonoids: a new class of in vitro apoptogenic agents from Sophora flavescens.
Toxicol In Vitro.    impact factor:   1.136
2000;  14(5): 429-33

8:  Kyogoku K, Hatayama K, Komatsu M.
Constituents of Chinese crude drug "Kushen" (the root of Sophora flavescens Ait.). Isolation of five new flavonoids and formononetin.
Chem Pharm Bull (Tokyo).    impact factor:   1.117
1973;  21(12): 2733-8

9:  Roh S, Kim C, Lee M, Hwang S, Rang M, Yoon Y.
The hair growth promoting effect of Sophora flavescens extract and its molecular regulation.
J Dermatol Sci.    impact factor:   1.115
2002;  30(1): 43

10:  Tanaka T, Ito T, Iinuma M, Ohyama M, Ichise M, Tateishi Y.
Stilbene oligomers in roots of Sophora davidii.
Phytochemistry.    impact factor:   1.106
2000;  53(8): 1009-14

11:  Shi HC, Huang QY, Yamaji R, Inui H, Fujita T, Miyatake K, Nakano Y, Tada T, Nishimura K.
Suppression by water extracts of Sophora plants of sucrose-induced hyperglycemia in rats and inhibition of intestinal disaccharidases in vitro.
Biosci Biotechnol Biochem.    impact factor:   1.039
1998;  62(6): 1225-7

12:  Ma SC, Du J, But PP, Deng XL, Zhang YW, Ooi VE, Xu HX, Lee SH, Lee SF.
Antiviral Chinese medicinal herbs against respiratory syncytial virus.
J Ethnopharmacol.    impact factor:   .687
2002;  79(2): 205-11

13:  Yamahara J, Mochizuki M, Fujimura H, Takaishi Y, Yoshida M, Tomimatsu T, Tamai Y.
Antiulcer action of Sophora flavescens root and an active constituent. I.
J Ethnopharmacol.    impact factor:   .687
1990;  29(2): 173-7

14:  Yamahara J, Kobayashi G, Iwamoto M, Chisaka T, Fujimura H, Takaishi Y, Yoshida M, Tomimatsu T, Tamai Y.
Vasodilatory active principles of Sophora flavescens root.
J Ethnopharmacol.    impact factor:   .687
1990;  29(1): 79-85

15:  Toda S, Shirataki Y.
Inhibitory effects of echinoisoflavanone and sophoraisoflavanone D in Sophora chrysophylla SEEM on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro.
Phytother Res.    impact factor:   .364
2002;  16(4): 309-11

16:  Komatsu M, Yokoe I, Shirataki Y.
[Studies on the constituents of Sophora species. X. Constituents of the root of Sophora japonica L. (author's transl)]
Yakugaku Zasshi.    impact factor:   .238
1976;  96(2): 254-7

17:  Komatsu M, Tomimori T, Hatayama K, Mikuriya N.
[Studies on the constituents of Sophora species. IV. Constituents of the root of Sophora angustifolia Sieb. et Zucc]
Yakugaku Zasshi.    impact factor:   .238
1970;  90(4): 463-8

18:  Komatsu M, Tomimori T, Hatayama K, Makiguchi Y.
[Studies on the constituents of Sophora species. 3. Constituents of the root of Sophora subprostrata Chun et T. Chen]
Yakugaku Zasshi.    impact factor:   .238
1970;  90(4): 459-62

19:  Drew AK, Bensoussan A, Whyte IM, Dawson AH, Zhu X, Myers SP.
Chinese herbal medicine toxicology database: monograph on Radix Sophorae Flavescentis, "ku shen".
J Toxicol Clin Toxicol.    impact factor:   0
2002;  40(2): 173-6

20:  Ku YR, Chang LY, Lin JH, Ho LK.
Determination of matrine and oxymatrine in Sophora subprostata by CE.
J Pharm Biomed Anal.    impact factor:   0
2002;  28(5): 1005-10

21:  Deng Y, Yang L, Qiu X, Dong Y.
[Study on the quality standards for xianghe suppository]
Zhong Yao Cai.    impact factor:   0
2001;  24(9): 672-3

22:  Kang SS, Kim JS, Son KH, Chang HW, Kim HP.
A new prenylated flavanone from the roots of Sophora flavescens.
Fitoterapia.    impact factor:   0
2000;  71(5): 511-5

23:  Li S, Wang S.
[Determination of alkaloids in radix Sophorae flavescentis by high performance capillary electrophoresis]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1999;  24(2): 100-2, 126

24:  Wu C, Zhou Z, He Y.
[Identification and determination of Shenbaiye]
Hua Xi Yi Ke Da Xue Xue Bao.    impact factor:   0
1998;  29(3): 334-7

25:  Wang X, Li J, Wei L, Zhang L, An D.
[Radix Sophorae flavescentis quality by chemical pattern recognition]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1996;  21(4): 198-200, 254

26:  Lu Y, Yang Z, Dong Y.
[Changes of chemical constituents of radix Sophorae flavescentis in complex formulas of traditional Chinese medicine]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1996;  21(7): 412-4, 447

27:  Wang X, Li J, Wei L, Zhang L, An D.
[Application of adaptive resonance theory network to the quality evaluation of radix Sophorae flavescentis]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1996;  21(7): 391-3, 446

28:  Yang J, Liu W, Chen Y, Zhong X, Qin Y.
[Examination on extraction technology for radix Sophorae Flavescentis by means of orthogonal experiment design]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1995;  20(6): 346-8, 383

29:  Chen ZS, Nie ZW, Sun QL.
[Clinical study in treating intractable ulcerative colitis with traditional Chinese medicine]
Zhongguo Zhong Xi Yi Jie He Za Zhi.    impact factor:   0
1994;  14(7): 400-2

30:  Tsuchiya H, Sato M, Iinuma M, Yokoyama J, Ohyama M, Tanaka T, Takase I, Namikawa I.
Inhibition of the growth of cariogenic bacteria in vitro by plant flavanones.
Experientia.    impact factor:   0
1994;  50(9): 846-9

31:  Hu S, Cai W, Ye J, Qian Z, Sun Z.
Influence of medicinal herbs on phagocytosis by bovine neutrophils.
Zentralbl Veterinarmed A.    impact factor:   0
1992;  39(8): 593-9

32:  Chuang CY, Xiao JG, Chiou GC.
Ocular anti-inflammatory actions of matrine.
J Ocul Pharmacol.    impact factor:   0
1987;  3(2): 129-34

33:  Wang JZ, Sun FL, Han HW, Zhang BH, Yuan JS, Ma L.
[Effect of total flavones of Sophora flavescens root on arrhythmia of cultured rat heart cells]
Zhongguo Yao Li Xue Bao.    impact factor:   0
1983;  4(1): 32-5


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