Ingredient ID 265 
Chinese Pronunciation ZIZHI 
English Name Chinese Ganoderma  
Latin Name Ganoderma Sinensis  
Aliases HeiZhi
Cancers Stomach
Identified Compounds

order by name

1. Trehalose (alpha:alpha)

   C12H22O11   342.29

2. Trehalose (alpha:beta)

   C12H22O11   342.29

3. Trehalose (beta:beta)

   C12H22O11   342.29

Recipes that contain
  1. 48      DangGuiLiGanTang
  2. 279      DangGuiLiGanTang
  3. 279      DangGuiLiGanTang
  4. 279      DangGuiLiGanTang

Available references (order by impact factor):

1:  Kim HS, Kacew S, Lee BM.
In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor).
Carcinogenesis.    impact factor:   4.118
1999;  20(8): 1637-40

2:  Cheung WM, Hui WS, Chu PW, Chiu SW, Ip NY.
Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells.
FEBS Lett.    impact factor:   3.72
2000;  486(3): 291-6

3:  Wang SY, Hsu ML, Hsu HC, Tzeng CH, Lee SS, Shiao MS, Ho CK.
The anti-tumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes.
Int J Cancer.    impact factor:   3.545
1997;  70(6): 699-705

4:  Su CY, Shiao MS, Wang CT.
Differential effects of ganodermic acid S on the thromboxane A2-signaling pathways in human platelets.
Biochem Pharmacol.    impact factor:   2.755
1999;  58(4): 587-95

5:  Cheung HY, Ng CW, Hood DJ.
Identification and quantification of base and nucleoside markers in extracts of Ganoderma lucidum, Ganoderma japonicum and Ganoderma capsules by micellar electrokinetic chromatography.
J Chromatogr A.    impact factor:   2.52
2001;  911(1): 119-26

6:  Haak-Frendscho M, Kino K, Sone T, Jardieu P.
Ling Zhi-8: a novel T cell mitogen induces cytokine production and upregulation of ICAM-1 expression.
Cell Immunol.    impact factor:   2.252
1993;  150(1): 101-13

7:  Hung WS, Fang CL, Su CH, Lai WF, Chang YC, Tsai YH.
Cytotoxicity and immunogenicity of SACCHACHITIN and its mechanism of action on skin wound healing.
J Biomed Mater Res.    impact factor:   2.038
2001;  56(1): 93-100

8:  Wang YY, Khoo KH, Chen ST, Lin CC, Wong CH, Lin CH.
Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities.
Bioorg Med Chem.    impact factor:   1.799
2002;  10(4): 1057-62

9:  Ma J, Ye Q, Hua Y, Zhang D, Cooper R, Chang MN, Chang JY, Sun HH.
New lanostanoids from the mushroom Ganoderma lucidum.
J Nat Prod.    impact factor:   1.652
2002;  65(1): 72-5

10:  Wu TS, Shi LS, Kuo SC.
Cytotoxicity of Ganoderma lucidum triterpenes.
J Nat Prod.    impact factor:   1.652
2001;  64(8): 1121-2

11:  Su HJ, Fann YF, Chung MI, Won SJ, Lin CN.
New lanostanoids of Ganoderma tsugae.
J Nat Prod.    impact factor:   1.652
2000;  63(4): 514-6

12:  Liu X, Yuan JP, Chung CK, Chen XJ.
Antitumor activity of the sporoderm-broken germinating spores of Ganoderma lucidum.
Cancer Lett.    impact factor:   1.518
2002;  182(2): 155-61

13:  Lai NS, Lin RH, Lai RS, Kun UC, Leu SC.
Prevention of autoantibody formation and prolonged survival in New Zealand Black/New Zealand White F1 mice with an ancient Chinese herb, Ganoderma tsugae.
Lupus.    impact factor:   1.464
2001;  10(7): 461-5

14:  Min BS, Gao JJ, Hattori M, Lee HK, Kim YH.
Anticomplement activity of terpenoids from the spores of Ganoderma lucidum.
Planta Med.    impact factor:   1.438
2001;  67(9): 811-4

15:  Hsieh TC, Wu JM.
Mechanism of action of herbal supplement PC-SPES: elucidation of effects of individual herbs of PC-SPES on proliferation and prostate specific gene expression in androgen-dependent LNCaP cells.
Int J Oncol.    impact factor:   1.381
2002;  20(3): 583-8

16:  Yun TK.
Update from Asia. Asian studies on cancer chemoprevention.
Ann N Y Acad Sci.    impact factor:   1.381
1999;  889: 157-92

17:  Lieu CW, Lee SS, Wang SY.
The effect of Ganoderma lucidum on induction of differentiation in leukemic U937 cells.
Anticancer Res.    impact factor:   1.375
1992;  12(4): 1211-5

18:  Won SJ, Lin MT, Wu WL.
Ganoderma tsugae mycelium enhances splenic natural killer cell activity and serum interferon production in mice.
Jpn J Pharmacol.    impact factor:   1.317
1992;  59(2): 171-6

19:  Ooi LS, Liu F, Ooi VE, Ng TB, Fung MC.
Gene expression of immunomodulatory cytokines induced by Narcissus tazetta lectin in the mouse.
Biochem Cell Biol.    impact factor:   1.268
2002;  80(2): 271-7

20:  Chiu SW, Wang ZM, Leung TM, Moore D.
Nutritional value of ganoderma extract and assessment of its genotoxicity and antigenotoxicity using comet assays of mouse lymphocytes.
Food Chem Toxicol.    impact factor:   1.243
2000;  38(2-3): 173-8

21:  Su C, Shiao M, Wang C.
Potentiation of ganodermic acid S on prostaglandin E(1)-induced cyclic AMP elevation in human platelets.
Thromb Res.    impact factor:   1.207
2000;  99(2): 135-45

22:  Su CH, Yang YZ, Ho HO, Hu CH, Sheu MT.
High-performance liquid chromatographic analysis for the characterization of triterpenoids from Ganoderma.
J Chromatogr Sci.    impact factor:   1.199
2001;  39(3): 93-100

23:  Shimizu A, Yano T, Saito Y, Inada Y.
Isolation of an inhibitor of platelet aggregation from a fungus, Ganoderma lucidum.
Chem Pharm Bull (Tokyo).    impact factor:   1.117
1985;  33(7): 3012-5

24:  el-Mekkawy S, Meselhy MR, Nakamura N, Tezuka Y, Hattori M, Kakiuchi N, Shimotohno K, Kawahata T, Otake T.
Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum.
Phytochemistry.    impact factor:   1.106
1998;  49(6): 1651-7

25:  Kawagishi H, Mitsunaga S, Yamawaki M, Ido M, Shimada A, Kinoshita T, Murata T, Usui T, Kimura A, Chiba S.
A lectin from mycelia of the fungus Ganoderma lucidum.
Phytochemistry.    impact factor:   1.106
1997;  44(1): 7-10

26:  Lu H, Kyo E, Uesaka T, Katoh O, Watanabe H.
Prevention of development of N,N'-dimethylhydrazine-induced colon tumors by a water-soluble extract from cultured medium of Ganoderma lucidum (Rei-shi) mycelia in male ICR mice.
Int J Mol Med.    impact factor:   1.058
2002;  9(2): 113-7

27:  Kim KC, Kim IG.
Ganoderma lucidum extract protects DNA from strand breakage caused by hydroxyl radical and UV irradiation.
Int J Mol Med.    impact factor:   1.058
1999;  4(3): 273-7

28:  Bao X, Fang J, Li X.
Structural characterization and immunomodulating activity of a complex glucan from spores of Ganoderma lucidum.
Biosci Biotechnol Biochem.    impact factor:   1.039
2001;  65(11): 2384-91

29:  Zhang J, Wang G, Li H, Zhuang C, Mizuno T, Ito H, Mayuzumi H, Okamoto H, Li J.
Antitumor active protein-containing glycans from the Chinese mushroom songshan lingzhi, Ganoderma tsugae mycelium.
Biosci Biotechnol Biochem.    impact factor:   1.039
1994;  58(7): 1202-5

30:  Wang G, Zhang J, Mizuno T, Zhuang C, Ito H, Mayuzumi H, Okamoto H, Li J.
Antitumor active polysaccharides from the Chinese mushroom Songshan lingzhi, the fruiting body of Ganoderma tsugae.
Biosci Biotechnol Biochem.    impact factor:   1.039
1993;  57(6): 894-900

31:  Zhang GL, Wang YH, Ni W, Teng HL, Lin ZB.
Hepatoprotective role of Ganoderma lucidum polysaccharide against BCG-induced immune liver injury in mice.
World J Gastroenterol.    impact factor:   .993
2002;  8(4): 728-33

32:  Lin JM, Lin CC, Chen MF, Ujiie T, Takada A.
Radical scavenger and antihepatotoxic activity of Ganoderma formosanum, Ganoderma lucidum and Ganoderma neo-japonicum.
J Ethnopharmacol.    impact factor:   .687
1995;  47(1): 33-41

33:  Xiao PG, Xing ST, Wang LW.
Immunological aspects of Chinese medicinal plants as antiageing drugs.
J Ethnopharmacol.    impact factor:   .687
1993;  38(2-3): 167-75

34:  Ke W, Ho H, Tsai T, Sheu M.
Sustained-release effect of codried excipients of microcrystalline cellulose and Ganoderma fiber.
Eur J Pharm Biopharm.    impact factor:   .616
2001;  51(3): 215-9

35:  Shieh YH, Liu CF, Huang YK, Yang JY, Wu IL, Lin CH, Li SC.
Evaluation of the hepatic and renal-protective effects of Ganoderma lucidum in mice.
Am J Chin Med.    impact factor:   .583
2001;  29(3-4): 501-7

36:  Hijikata Y, Yamada S.
Effect of Ganoderma lucidum on postherpetic neuralgia.
Am J Chin Med.    impact factor:   .583
1998;  26(3-4): 375-81

37:  Chen WC, Hau DM, Lee SS.
Effects of Ganoderma lucidum and krestin on cellular immunocompetence in gamma-ray-irradiated mice.
Am J Chin Med.    impact factor:   .583
1995;  23(1): 71-80

38:  Wang WK, Chen HL, Hsu TL, Wang YY.
Alteration of pulse in human subjects by three Chinese herbs.
Am J Chin Med.    impact factor:   .583
1994;  22(2): 197-203

39:  Lin JM, Lin CC, Chiu HF, Yang JJ, Lee SG.
Evaluation of the anti-inflammatory and liver-protective effects of anoectochilus formosanus, ganoderma lucidum and gynostemma pentaphyllum in rats.
Am J Chin Med.    impact factor:   .583
1993;  21(1): 59-69

40:  Gau JP, Lin CK, Lee SS, Wang SR.
The lack of antiplatelet effect of crude extracts from ganoderma lucidum on HIV-positive hemophiliacs.
Am J Chin Med.    impact factor:   .583
1990;  18(3-4): 175-9

41:  Hsu HY, Lian SL, Lin CC.
Radioprotective effect of Ganoderma lucidum (Leyss. ex. Fr.) Karst after X-ray irradiation in mice.
Am J Chin Med.    impact factor:   .583
1990;  18(1-2): 61-9

42:  Lee JM, Kwon H, Jeong H, Lee JW, Lee SY, Baek SJ, Surh YJ.
Inhibition of lipid peroxidation and oxidative DNA damage by Ganoderma lucidum.
Phytother Res.    impact factor:   .364
2001;  15(3): 245-9

43:  Zhu M, Chang Q, Wong LK, Chong FS, Li RC.
Triterpene antioxidants from ganoderma lucidum.
Phytother Res.    impact factor:   .364
1999;  13(6): 529-31

44:  Gao XX, Fei XF, Wang BX, Zhang J, Gong YJ, Minami M, Nagata T, Ikejima T.
Effects of polysaccharides (FI0-b) from mycelium of Ganoderma tsugae on proinflammatory cytokine production by THP-1 cells and human PBMC (I).
Acta Pharmacol Sin.    impact factor:   .196
2000;  21(12): 1179-85

45:  Gao XX, Wang BX, Fei XF, Zhang J, Gong YJ, Minami M, Nagata T, Ikejima T.
Effects of polysaccharides (FI0-c) from mycelium of Ganoderma tsugae on proinflammatory cytokine production by THP-1 cells and human PBMC (II).
Acta Pharmacol Sin.    impact factor:   .196
2000;  21(12): 1186-92

46:  Ming D, Chilton J, Fogarty F, Towers GH.
Chemical constituents of Ganoderma applanatum of British Columbia forests.
Fitoterapia.    impact factor:   0
2002;  73(2): 147-52

47:  Zhong L, Jiang D, Wang Q.
[Effects of Ganoderma lucidum (Leyss ex Fr) Karst compound on the proliferation and differentiation of K562 leukemic cells]
Hunan Yi Ke Da Xue Xue Bao.    impact factor:   0
1999;  24(6): 521-4

48:  Zhang Q, Lin Z.
[Study on antitumor activity and mechanism of Ganoderma polysaccharides B]
Zhongguo Zhong Xi Yi Jie He Za Zhi.    impact factor:   0
1999;  19(9): 544-7

49:  Woo YA, Kim HJ, Cho JH, Chung H.
Discrimination of herbal medicines according to geographical origin with near infrared reflectance spectroscopy and pattern recognition techniques.
J Pharm Biomed Anal.    impact factor:   0
1999;  21(2): 407-13

50:  Patocka J.
Anti-inflammatory triterpenoids from mysterious mushroom Ganoderma lucidum and their potential possibility in modern medicine.
Acta Medica (Hradec Kralove).    impact factor:   0
1999;  42(4): 123-5

51:  Lu L, Qian Y, Hu Z, Ye Y.
[Study on certified reference material of germanium in Ganoderma lucidum]
Wei Sheng Yan Jiu.    impact factor:   0
1998;  27(4): 283-4

52:  Wen Z, Li J, He S, Xiong S, He X.
[Effect of Ganoderma japonicum (Fr.) Lloyd mixture on experimental thrombosis]
Hunan Yi Ke Da Xue Xue Bao.    impact factor:   0
1997;  22(1): 15-8

53:  Li T, He Y, Li R.
[Chemical studies on peptidepolysaccharides of Ganoderma lucidum (W. Curt. Fr.) Karst.]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1997;  22(8): 487-9, 512

54:  Chai H, Wang F, Zhang Z, Yang J, Zhang Y.
[Constituents from the fruiting body of Ganoderma lucidum (Fr.) Karst]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1997;  22(9): 552-3, 576

55:  Wang FS, Cai H, Yang JS, Zhang YM, Hou CY, Liu JQ, Zhao MJ.
[Studies on the ganoderic acid, a new constituents from the fruiting body of Ganoderma lucidum (Fr.) Karst]
Yao Xue Xue Bao.    impact factor:   0
1997;  32(6): 447-50

56:  Lu ZW.
[Psychoneuroimmunological effects of morphine and the immunoprotection of Ganoderma polysaccharides peptide in morphine-dependent mice]
Sheng Li Ke Xue Jin Zhan.    impact factor:   0
1995;  26(1): 45-9

57:  Zhang LX, Mong H, Zhou XB.
[Effect of Japanese Ganoderma Lucidum on production of interleukin-2 from murine splenocytes]
Zhongguo Zhong Xi Yi Jie He Za Zhi.    impact factor:   0
1993;  13(10): 613-5, 582

58:  Lei LS, Lin ZB.
[Effects of Ganoderma polysaccharides on the activity of DNA polymerase alpha of splenocytes and immune function in aged mice]
Yao Xue Xue Bao.    impact factor:   0
1993;  28(8): 577-82

59:  Chen K, Li C.
Recent advances in studies on traditional Chinese anti-aging materia medica.
J Tradit Chin Med.    impact factor:   0
1993;  13(3): 223-6, contd

60:  Wan F, Huang D.
[Anti-inflammatory and analgesic actions of artificial and fermentative Ganoderma sinense (AFGS)]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1992;  17(10): 619-22, 640

61:  Chen RY, Yu DQ.
[Studies on the triterpenoid constituents of the spores from Ganoderma lucidum karst]
Yao Xue Xue Bao.    impact factor:   0
1991;  26(4): 267-73

62:  Chen RY, Yu DQ.
[Application of 2d NMR techniques in the structure determination of ganosporelactone A and B]
Yao Xue Xue Bao.    impact factor:   0
1991;  26(6): 430-6

63:  Tao J, Feng KY.
Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation.
J Tongji Med Univ.    impact factor:   0
1990;  10(4): 240-3

64:  Yu JG, Chen RY, Yao ZX, Zhai YF, Yang SL, Ma JL.
[Studies on constituents of ganoderma capense IV. The chemical structures of ganoine, ganodine and ganoderpurine]
Yao Xue Xue Bao.    impact factor:   0
1990;  25(8): 612-6

65:  Chen RY, Yu DQ.
[Progress of studies on the chemical constituents of Ganoderma triterpene]
Yao Xue Xue Bao.    impact factor:   0
1990;  25(12): 940-53

66:  Zhang GD, Liu HY, Liang YH.
[Reverse phase HPLC determination of nucleosides and their bases in the submerged culture of Ganoderma capense]
Yao Xue Xue Bao.    impact factor:   0
1986;  21(1): 35-9

67:  Wang JF, Zhang JJ, Chen WW.
Study of the action of Ganoderma lucidum on scavenging hydroxyl radicals from plasma.
J Tradit Chin Med.    impact factor:   0
1985;  5(1): 55-60

68:  Xu J, Zhong QP, Lu D.
[Effect of ganoderma extract on murine immunocytes]
Zhongguo Yi Xue Ke Xue Yuan Xue Bao.    impact factor:   0
1985;  7(4): 301-4

69:  Fu HD, Wang ZY.
The clinical effects of Ganoderma lucidum spore preparations in 10 cases of atrophic myotonia.
J Tradit Chin Med.    impact factor:   0
1982;  2(1): 63-5

70:  Chen JH, Jiang RL.
[A pharmacological study of the Chinese drug lingzhi (ganoderma) (author's transl)]
Yao Xue Xue Bao.    impact factor:   0
1980;  15(4): 234-44


Responsed in 1328 milliseconds.

Webpage designed by Dr. Xueliang Fang, last updated on 3/10/2005