Ingredient ID 266 
Chinese Pronunciation ZICAO 
English Name Gromwell Root  
Latin Name Radix Lithospermi  
Aliases YingZiCao
DaZiCao
HongTiaoZiCao  
Cancers Chorioepithelioma
Leukemia
Lung
Liver
Cervical
Stomach
Breast  
Identified Compounds
17

order by ID

1. Acetylshikonin

   C18H18O6   330.33
  ID:83

2. Alpha-methyl-n-butyrylshikonin

   C21H24O6   372.41
  ID:4266

3. Beta,beta-dimethylacrylalkanin

      

4. Beta,beta-dimethylacryloylshikonin

   C21H22O6   370.4
  ID:1889

5. Beta-hydroxyisovalerylalkanin

      

6. Beta-hydroxyisovalerylshikonin

   C21H24O7   388.41
  ID:3215

7. Isobutyryl Shikonin

   C20H22O6   358.39
  ID:3447

8. Isovalerylshikonin

   C21H24O6   372.41
  ID:3614

9. Lithospermidin A

   C21H24O7   388.41
  ID:3934

10. Lithospermidin B

   C21H24O7   388.41
  ID:3935

11. Shikonin

   C16H16O5   288.3
NSC# 252844 Activity (<1uM)
  ID:5850

12. Shikonofuran A

   C18H20O5   316.35
  ID:7687

13. Shikonofuran B

   C21H26O5   358.43
  ID:7688

14. Shikonofuran C

   C21H26O5   358.43
  ID:7689

15. Shikonofuran D

   C20H24O5   344.4
  ID:7690

16. Shikonofuran E

   C21H24O5   356.42
  ID:7691

17. Teracrylshikonin

   C23H26O6   398.45
  ID:7737

 
Recipes that contain
ZICAO
  1. 3      KangAiTang
  2. 19      LiQiJiangNiTang
  3. 41      FuZhengKangAiTang
  4. 52      FuRongFeiAiXiao
  5. 71      DiBoTang
  6. 73      ShengJinJieDuYin
  7. 74      ZiCaoGenTang
  8. 86      LongKuiTang
  9. 91      ErGenTang
  10. 93      ZiLongLianTang
  11. 115      LiangGenYiShenTang
  12. 118      HuangDuLiangGenTang
  13. 141      LiuXiaoGao
  14. 151      BaiXueBingFang
  15. 152      710JianJi
  16. 154      ChanLianTang
  17. 159      SheSheCaoTang
  18. 167      YiAiPian
  19. 186      XiaoZhongYiAiSan
  20. 202      GangMenAiFang
  21. 235      LiangGenTang
  22. 253      FuFangShanCiGuTang
  23. 253      FuFangShanCiGuTang
  24. 280      GuiSheTang
  25. 283      ErJiaTang
  26. 289      LongDanXieGanTang
  27. 335      GongJingWan(Fen)
  28. 341      Qi(San)PinDing
  29. 373      ZiLongLianTang
  30. 395      HuangDuLiangGenTang
  31. 417      ShiAiGao
  32. 439      ChanLianTang
  33. 440      XiaoDuQingXueTang
  34. 443      FuFangMaQianZiTang
  35. 455      BaiXueBingFangIII
  36. 466      YiAiPian
  37. 478      XiaoZhongYiAiSan
  38. 491      ShiGuanAiFangIV
  39. 517      HaiBanHeJi
  40. 519      GanAiFangVI
  41. 519      GanAiFangVI
 

Available references (order by impact factor):

1:  Kohle A, Sommer S, Yazaki K, Ferrer A, Boronat A, Li SM, Heide L.
High level expression of chorismate pyruvate-lyase (UbiC) and HMG-CoA reductase in hairy root cultures of Lithospermum erythrorhizon.
Plant Cell Physiol.    impact factor:   2.259
2002;  43(8): 894-902

2:  Jin R, Kurashige S.
Effects of Chinese herbs on macrophage functions in N-butyl-N-butanolnitrosoamine treated mice.
Immunopharmacol Immunotoxicol.    impact factor:   .761
1996;  18(1): 105-14

3:  Jin R, Wan LL, Mitsuishi T, Sato S, Akuzawa Y, Kodama K, Kurashige S.
Effect of shi-ka-ron and Chinese herbs on cytokine production of macrophage in immunocompromised mice.
Am J Chin Med.    impact factor:   .583
1994;  22(3-4): 255-66

4:  Kang JS, Ahn BZ, Blaschke G.
Enantiomeric ratio of shikonin derivatives as a possible key for the determination of the origin of lithospermi radix.
Arch Pharm Res.    impact factor:   .382
1998;  21(5): 565-9

5:  Chen X, Yang L, Oppenheim JJ, Howard MZ.
Cellular pharmacology studies of shikonin derivatives.
Phytother Res.    impact factor:   .364
2002;  16(3): 199-209

6:  Jin R, Wan LL, Mitsuishi T, Kodama K, Kurashige S.
[Immunomodulative effects of Chinese herbs in mice treated with anti-tumor agent cyclophosphamide]
Yakugaku Zasshi.    impact factor:   .238
1994;  114(7): 533-8

7:  Ozaki Y, Suga C, Yoshioka T, Morimoto T, Harada M.
[Evaluation on equivalence of pharmacological properties between natural crude drugs and their cultured cells based on their components. Accelerative effect of lithospermi radix and inhibitory effect of coptidis rhizoma on proliferation of granulation tissue]
Yakugaku Zasshi.    impact factor:   .238
1990;  110(4): 268-72

8:  Ueba N, Otake T, Yamazaki K, Mori H, Morimoto M.
[Anti-HIV-1 activities of crude drug, shikon (Lithospermi radix), in vitro]
Nippon Rinsho.    impact factor:   0
1993;  51 Suppl: 207-12

 

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