Ingredient ID 369 
Chinese Pronunciation DIBURONG 
English Name Epigeal Stephania Root  
Latin Name Radix Stephaniae Epigaeae  
Aliases DiBuRong
Cancers Sarcoma
Identified Compounds

order by name

1. Cepharanthine

   C37H38N2O6   606.72
NSC# 629744 Activity (<10uM)

2. Cycleanine

   C38H42N2O6   622.76
NSC# 615580 Activity (<1uM)

3. Sinoacutine

   C19H21NO4   327.38

4. Coculine

   C19H23NO4   329.39

5. Stephanine

   C19H19NO3   309.36

6. L-cassythicine

   C19H19NO4   325.36

7. L-dicentrine

   C20H21NO4   339.39
NSC# 251699 Activity (<10uM)

8. L-tetrahydropalmatine

   C21H25NO4   355.43

9. Dehydrodicentrine

   C20H19NO4   337.37

10. Dehydrostephanine

   C19H17NO3   307.35

11. Isostephodeline

   C21H27NO5   373.45

Recipes that contain

    Available references (order by impact factor):

    1:  Shen YC, Chou CJ, Chiou WF, Chen CF.
    Anti-inflammatory effects of the partially purified extract of radix Stephaniae tetrandrae: comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functions.
    Mol Pharmacol.    impact factor:   5.465
    2001;  60(5): 1083-90

    2:  Liu QY, Karpinski E, Rao MR, Pang PK.
    Tetrandrine: a novel calcium channel antagonist inhibits type I calcium channels in neuroblastoma cells.
    Neuropharmacology.    impact factor:   4.176
    1991;  30(12A): 1325-31

    3:  Yu XC, Wu S, Wang GY, Shan J, Wong TM, Chen CF, Pang KT.
    Cardiac effects of the extract and active components of radix stephaniae tetrandrae. II. Myocardial infarct, arrhythmias, coronary arterial flow and heart rate in the isolated perfused rat heart.
    Life Sci.    impact factor:   1.774
    2001;  68(25): 2863-72

    4:  Wu S, Yu XC, Shan J, Wong TM, Chen CF, Pang KT.
    Cardiac effects of the extract and active components of Radix stephaniae tetrandrae. I. Electrically-induced intracellular calcium transient and protein release during the calcium paradox.
    Life Sci.    impact factor:   1.774
    2001;  68(25): 2853-61

    5:  Kawashima K, Hayakawa T, Miwa Y, Oohata H, Suzuki T, Fujimoto K, Ogino T, Chen ZX.
    Structure and hypotensive activity relationships of tetrandrine derivatives in stroke-prone spontaneously hypertensive rats.
    Gen Pharmacol.    impact factor:   1.105
    1990;  21(3): 343-7

    6:  Rao MR.
    Effects of tetrandrine on cardiac and vascular remodeling.
    Acta Pharmacol Sin.    impact factor:   .196
    2002;  23(12): 1075-85

    7:  Wong TM, Wu S, Yu XC, Li HY.
    Cardiovascular actions of Radix Stephaniae Tetrandrae: a comparison with its main component, tetrandrine.
    Acta Pharmacol Sin.    impact factor:   .196
    2000;  21(12): 1083-8

    8:  Li X, Zhang S, Qin L.
    [Experimental study of analgesic effect of combined Radix Aconiti and Radix Stephaniae Tetrandrae]
    Zhongguo Zhong Xi Yi Jie He Za Zhi.    impact factor:   0
    2000;  20(3): 202-4

    9:  Wang SR, Sun B, Ding GM.
    [Animal experiments on meridian-reaching actions of traditional Chinese medicinal herbs]
    Zhongguo Zhong Yao Za Zhi.    impact factor:   0
    1994;  19(8): 500-2, 512

    10:  Yang YF, Zhao SX, Dong SS, Liu C.
    [Dual-wavelength TLC densitometric determination of alkaloids in radix Stephaniae tetrandrae]
    Zhong Yao Tong Bao.    impact factor:   0
    1988;  13(12): 36-7, 59-60

    11:  Chou LD.
    [Determination of aristolochic acid in radix Stephaniae tetradrae (Aristolochia fangchi)]
    Zhong Yao Tong Bao.    impact factor:   0
    1986;  11(6): 43-5


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