Ingredient ID 63 
Chinese Pronunciation BADOU 
English Name Croton Fruit  
Latin Name Fructus Crotonis  
Aliases JiangZi
JiangZi(SiChan; GuangXi)
Cancers Stomach
Identified Compounds

order by name

1. Crotonic Acid

   C4H6O2   86.09

2. Crotonoside

   C10H13N5O5   283.24

3. Linoleic Acid

   C18H32O2   280.45

4. Oleic Acid

   C18H34O2   282.46
NSC# 9856 Activity (<10uM)

5. Tiglic Acid

   C5H8O2   100.12

6. Crotin

   C4H8   56.11

7. 4-deoxy-4alpha-phorbol

   C20H28O5   348.43

8. Croton Oil Factor


9. Phorbol

   C20H28O6   364.43

Recipes that contain
  1. 146      KangXueDan
  2. 174      LaoLiuWan
  3. 285      XiaoAiGaoYao
  4. 317      BiAiFang
  5. 430      KangBaiDan

Available references (order by impact factor):

1:  Van Duuren BL, Orris L.
The tumor-enhancing principles of Croton tiglium L.
Cancer Res.    impact factor:   8.614
1965;  25(11): 1871-5

2:  Chen MH, Zhou KJ, Fu ZJ, Pan KZ.
Preliminary crystallographic studies of crotin II.
J Mol Biol.    impact factor:   5.501
1993;  234(3): 908-9

3:  Stirpe F, Pession-Brizzi A, Lorenzoni E, Strocchi P, Montanaro L, Sperti S.
Studies on the proteins from the seeds of Croton tiglium and of Jatropha curcas. Toxic properties and inhibition of protein synthesis in vitro.
Biochem J.    impact factor:   4.349
1976;  156(1): 1-6

4:  Bhatt T, Coombs M, O'Neill C.
Biogenic silica fibre promotes carcinogenesis in mouse skin.
Int J Cancer.    impact factor:   3.545
1984;  34(4): 519-28

5:  Salomi MJ, Nair SC, Panikkar KR.
Inhibitory effects of Nigella sativa and saffron (Crocus sativus) on chemical carcinogenesis in mice.
Nutr Cancer.    impact factor:   2.342
1991;  16(1): 67-72

6:  Ralison C, Creppy EE, Boulanger Y, Dirheimer G.
Purification and characterization of a toxin inhibiting protein synthesis from Croton mongue, a Madagascar Euphorbiaceae.
Biochimie.    impact factor:   1.594
1986;  68(10-11): 1225-30

7:  Banerjee S, Rao AR.
Promoting action of cashew nut shell oil in DMBA-initiated mouse skin tumour model system.
Cancer Lett.    impact factor:   1.518
1992;  62(2): 149-52

8:  Ganguly C, De S, Das S.
Prevention of carcinogen-induced mouse skin papilloma by whole fruit aqueous extract of Momordica charantia.
Eur J Cancer Prev.    impact factor:   1.287
2000;  9(4): 283-8

9:  el-Mekkawy S, Meselhy MR, Nakamura N, Hattori M, Kawahata T, Otake T.
12-O-acetylphorbol-13-decanoate potently inhibits cytopathic effects of human immunodeficiency virus type 1 (HIV-1), without activation of protein kinase C.
Chem Pharm Bull (Tokyo).    impact factor:   1.117
1999;  47(9): 1346-7

10:  El-Mekkawy S, Meselhy MR, Nakamura N, Hattori M, Kawahata T, Otake T.
Anti-HIV-1 phorbol esters from the seeds of Croton tiglium.
Phytochemistry.    impact factor:   1.106
2000;  53(4): 457-64

11:  Ahmed B, Alam T, Varshney M, Khan SA.
Hepatoprotective activity of two plants belonging to the Apiaceae and the Euphorbiaceae family.
J Ethnopharmacol.    impact factor:   .687
2002;  79(3): 313-6

12:  Latha PG, Panikkar KR.
Inhibition of chemical carcinogenesis by Psoralea corylifolia seeds.
J Ethnopharmacol.    impact factor:   .687
1999;  68(1-3): 295-8

13:  Asuzu IU, Shetty SN, Anika SM.
Effects of chronic oral administration in mice of the gut-stimulating crystals of Croton penduliflorus seed oil.
J Ethnopharmacol.    impact factor:   .687
1990;  30(2): 135-43

14:  Asuzu IU, Shetty SN, Anika SM.
Effects of the gut-stimulating principle in Croton penduliflorus seed oil on the central nervous system.
J Ethnopharmacol.    impact factor:   .687
1989;  26(2): 111-9

15:  Asuzu IU, Gray AI, Waterman PG.
The extraction, isolation and identification of the purgative component of Croton penduliflorus seed oil.
J Ethnopharmacol.    impact factor:   .687
1988;  23(2-3): 267-71

16:  Mazzanti G, Bolle P, Martinoli L, Piccinelli D, Grgurina I, Animati F, Mugne Y.
Croton macrostachys, a plant used in traditional medicine: purgative and inflammatory activity.
J Ethnopharmacol.    impact factor:   .687
1987;  19(2): 213-9

17:  Asuzu IU, Shetty SN, Anika SM.
The toxic effects of a chronic administration of the gut-stimulating principle in Croton penduliflorus hutch. seeds in mice.
Drug Chem Toxicol.    impact factor:   .458
1989;  12(1): 85-93

18:  Horgen FD, Edrada RA, de los Reyes G, Agcaoili F, Madulid DA, Wongpanich V, Angerhofer CK, Pezzuto JM, Soejarto DD, Farnsworth NR.
Biological screening of rain forest plot trees from Palawan Island (Philippines).
Phytomedicine.    impact factor:   .185
2001;  8(1): 71-81

19:  Ding M, Lin W.
[Analgesic anti-inflammatory effects of moschus bone-setting liquor in local traumatic ecchymosis]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1990;  15(1): 49-51, 65

20:  de Sousa MV, Morhy L.
Enterolobin, a hemolytic protein from Enterolobium contortisiliquum seeds (Leguminosae--Mimosoideae). Purification and characterization.
An Acad Bras Cienc.    impact factor:   0
1989;  61(4): 405-12

21:  Adolf W, Hecker E.
On the active principles of the spurge family. III. Skin irritant and cocarcinogenic factors from the caper spurge.
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol.    impact factor:   0
1975;  84(3): 325-44


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