Ingredient ID 65 
Chinese Pronunciation SHUIZHI 
English Name Leech  
Latin Name Hirudo  
Aliases MaZhi
Cancers Skin
Identified Compounds

order by name

1. Histamine

   C5H9N3   111.15

2. Antithrombin


3. Heparin


4. Hirudin


5. Antithromfin


Recipes that contain
  1. 5      DiAiWan
  2. 35      ZaoZhiSan
  3. 40      QiChongSan
  4. 43      GanAiYiHaoSan
  5. 46      WuChongWan
  6. 141      LiuXiaoGao
  7. 173      TuoDuWan
  8. 190      LuanChaoAiFangSan
  9. 209      DiAiWan
  10. 220      ShuangRenSan
  11. 230      WuGongGongDuTang
  12. 266      ZaoZhiSan
  13. 270      QiChongSan
  14. 277      WuChongWan
  15. 284      GanAiFang
  16. 352      YuHuangWan
  17. 355      LongSheXiaoLiuWan
  18. 422      LiuXiaoGao
  19. 469      TuoDuWan
  20. 501      WeiAiFangIV
  21. 502      LongSheXiaoLiuWan
  22. 519      GanAiFangVI

Available references (order by impact factor):

1:  Sulzer D, Edwards R.
Vesicles: equal in neurotransmitter concentration but not in volume.
Neuron.    impact factor:   16.782
2000;  28(1): 5-7

2:  Bruns D, Riedel D, Klingauf J, Jahn R.
Quantal release of serotonin.
Neuron.    impact factor:   16.782
2000;  28(1): 205-20

3:  Cacciatore TW, Brodfuehrer PD, Gonzalez JE, Jiang T, Adams SR, Tsien RY, Kristan WB Jr, Kleinfeld D.
Identification of neural circuits by imaging coherent electrical activity with FRET-based dyes.
Neuron.    impact factor:   16.782
1999;  23(3): 449-59

4:  Richardson JL, Kroger B, Hoeffken W, Sadler JE, Pereira P, Huber R, Bode W, Fuentes-Prior P.
Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor.
EMBO J.    impact factor:   13.973
2000;  19(21): 5650-60

5:  Reverter D, Fernandez-Catalan C, Baumgartner R, Pfander R, Huber R, Bode W, Vendrell J, Holak TA, Aviles FX.
Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Nat Struct Biol.    impact factor:   13.555
2000;  7(4): 322-8

6:  Roemer J.
Leeches latch on after reconstructive surgery.
J Natl Cancer Inst.    impact factor:   12.945
1999;  91(20): 1714-6

7:  Shah S.
Why leeches influence my physical examination.
Lancet.    impact factor:   10.197
1998;  352(9145): 2014-5

8:  Huang FZ, Kang D, Ramirez-Weber FA, Bissen ST, Weisblat DA.
Micromere lineages in the glossiphoniid leech Helobdella.
Development.    impact factor:   10.088
2002;  129(3): 719-32

9:  Song MH, Huang FZ, Chang GY, Weisblat DA.
Expression and function of an even-skipped homolog in the leech Helobdella robusta.
Development.    impact factor:   10.088
2002;  129(15): 3681-92

10:  Arai A, Nakamoto A, Shimizu T.
Specification of ectodermal teloblast lineages in embryos of the oligochaete annelid Tubifex: involvement of novel cell-cell interactions.
Development.    impact factor:   10.088
2001;  128(7): 1211-9

11:  Bely AE, Wray GA.
Evolution of regeneration and fission in annelids: insights from engrailed- and orthodenticle-class gene expression.
Development.    impact factor:   10.088
2001;  128(14): 2781-91

12:  Seaver EC, Shankland M.
Establishment of segment polarity in the ectoderm of the leech Helobdella.
Development.    impact factor:   10.088
2001;  128(9): 1629-41

13:  Shain DH, Stuart DK, Huang FZ, Weisblat DA.
Segmentation of the central nervous system in leech.
Development.    impact factor:   10.088
2000;  127(4): 735-44

14:  Isaksen DE, Liu NJ, Weisblat DA.
Inductive regulation of cell fusion in leech.
Development.    impact factor:   10.088
1999;  126(15): 3381-90

15:  Gershon TR, Baker MW, Nitabach M, Macagno ER.
The leech receptor protein tyrosine phosphatase HmLAR2 is concentrated in growth cones and is involved in process outgrowth.
Development.    impact factor:   10.088
1998;  125(7): 1183-90

16:  Stoker AW.
Receptor tyrosine phosphatases in axon growth and guidance.
Curr Opin Neurobiol.    impact factor:   9.287
2001;  11(1): 95-102

17:  Skinner FK, Mulloney B.
Intersegmental coordination in invertebrates and vertebrates.
Curr Opin Neurobiol.    impact factor:   9.287
1998;  8(6): 725-32

18:  Masino MA, Calabrese RL.
A functional asymmetry in the Leech Heartbeat Timing Network is revealed by driving the network across various cycle periods.
J Neurosci.    impact factor:   8.955
2002;  22(11): 4418-27

19:  Zoccolan D, Torre V.
Using optical flow to characterize sensory-motor interactions in a segment of the medicinal leech.
J Neurosci.    impact factor:   8.955
2002;  22(6): 2283-98

20:  Cymbalyuk GS, Gaudry Q, Masino MA, Calabrese RL.
Bursting in leech heart interneurons: cell-autonomous and network-based mechanisms.
J Neurosci.    impact factor:   8.955
2002;  22(24): 10580-92

21:  Zoccolan D, Pinato G, Torre V.
Highly variable spike trains underlie reproducible sensorimotor responses in the medicinal leech.
J Neurosci.    impact factor:   8.955
2002;  22(24): 10790-800

22:  Esch T, Mesce KA, Kristan WB.
Evidence for sequential decision making in the medicinal leech.
J Neurosci.    impact factor:   8.955
2002;  22(24): 11045-54

23:  Burrell BD, Sahley CL, Muller KJ.
Non-associative learning and serotonin induce similar bi-directional changes in excitability of a neuron critical for learning in the medicinal leech.
J Neurosci.    impact factor:   8.955
2001;  21(4): 1401-12

24:  Kumar SM, Porterfield DM, Muller KJ, Smith PJ, Sahley CL.
Nerve injury induces a rapid efflux of nitric oxide (NO) detected with a novel NO microsensor.
J Neurosci.    impact factor:   8.955
2001;  21(1): 215-20

25:  Xie Y, Yeo TT, Zhang C, Yang T, Tisi MA, Massa SM, Longo FM.
The leukocyte common antigen-related protein tyrosine phosphatase receptor regulates regenerative neurite outgrowth in vivo.
J Neurosci.    impact factor:   8.955
2001;  21(14): 5130-8

26:  Ivanov AI, Calabrese RL.
Intracellular Ca2+ dynamics during spontaneous and evoked activity of leech heart interneurons: low-threshold Ca currents and graded synaptic transmission.
J Neurosci.    impact factor:   8.955
2000;  20(13): 4930-43

27:  Cang J, Friesen WO.
Sensory modification of leech swimming: rhythmic activity of ventral stretch receptors can change intersegmental phase relationships.
J Neurosci.    impact factor:   8.955
2000;  20(20): 7822-9

28:  Cacciatore TW, Rozenshteyn R, Kristan WB Jr.
Kinematics and modeling of leech crawling: evidence for an oscillatory behavior produced by propagating waves of excitation.
J Neurosci.    impact factor:   8.955
2000;  20(4): 1643-55

29:  Chen A, Kumar SM, Sahley CL, Muller KJ.
Nitric oxide influences injury-induced microglial migration and accumulation in the leech CNS.
J Neurosci.    impact factor:   8.955
2000;  20(3): 1036-43

30:  Yu X, Nguyen B, Friesen WO.
Sensory feedback can coordinate the swimming activity of the leech.
J Neurosci.    impact factor:   8.955
1999;  19(11): 4634-43

31:  Wessel R, Kristan WB Jr, Kleinfeld D.
Supralinear summation of synaptic inputs by an invertebrate neuron: dendritic gain is mediated by an "inward rectifier" K(+) current.
J Neurosci.    impact factor:   8.955
1999;  19(14): 5875-88

32:  Wessel R, Kristan WB Jr, Kleinfeld D.
Dendritic Ca(2+)-activated K(+) conductances regulate electrical signal propagation in an invertebrate neuron.
J Neurosci.    impact factor:   8.955
1999;  19(19): 8319-26

33:  Reese D, Drapeau P.
Neurite growth patterns leading to functional synapses in an identified embryonic neuron.
J Neurosci.    impact factor:   8.955
1998;  18(15): 5652-62

34:  Lewis JE, Kristan WB Jr.
Quantitative analysis of a directed behavior in the medicinal leech: implications for organizing motor output.
J Neurosci.    impact factor:   8.955
1998;  18(4): 1571-82

35:  Gershon TR, Baker MW, Nitabach M, Wu P, Macagno ER.
Two receptor tyrosine phosphatases of the LAR family are expressed in the developing leech by specific central neurons as well as select peripheral neurons, muscles, and other cells.
J Neurosci.    impact factor:   8.955
1998;  18(8): 2991-3002

36:  Huang FZ, Bely AE, Weisblat DA.
Stochastic WNT signaling between nonequivalent cells regulates adhesion but not fate in the two-cell leech embryo.
Curr Biol.    impact factor:   8.733
2001;  11(1): 1-7

37:  Baker MW, Macagno ER.
RNAi of the receptor tyrosine phosphatase HmLAR2 in a single cell of an intact leech embryo leads to growth-cone collapse.
Curr Biol.    impact factor:   8.733
2000;  10(17): 1071-4

38:  Salamanca S, Villegas V, Vendrell J, Li L, Aviles FX, Chang JY.
The unfolding pathway of leech carboxypeptidase inhibitor.
J Biol Chem.    impact factor:   7.666
2002;  277(20): 17538-43

39:  Xu YZ, Ji Y, Zipser B, Jellies J, Johansen KM, Johansen J.
Proteolytic cleavage of the ectodomain of the L1 CAM-family member tractin.
J Biol Chem.    impact factor:   7.666
2002;  ;[e-pub ahead of print]  40:  Salzet M, Chopin V, Baert J, Matias I, Malecha J.
Theromin, a novel leech thrombin inhibitor.
J Biol Chem.    impact factor:   7.666
2000;  275(40): 30774-80

41:  Chopin V, Salzet M, Baert J, Vandenbulcke F, Sautiere PE, Kerckaert JP, Malecha J.
Therostasin, a novel clotting factor Xa inhibitor from the rhynchobdellid leech, Theromyzon tessulatum.
J Biol Chem.    impact factor:   7.666
2000;  275(42): 32701-7

42:  Leech AP, Boetzel R, McDonald C, Shrive AK, Moore GR, Coggins JR, Sawyer L, Kleanthous C.
Re-evaluating the role of His-143 in the mechanism of type I dehydroquinase from Escherichia coli using two-dimensional 1H,13C NMR.
J Biol Chem.    impact factor:   7.666
1998;  273(16): 9602-7

43:  Hirabayashi J, Dutta SK, Kasai K.
Novel galactose-binding proteins in Annelida. Characterization of 29-kDa tandem repeat-type lectins from the earthworm Lumbricus terrestris.
J Biol Chem.    impact factor:   7.666
1998;  273(23): 14450-60

44:  Schulz JR, Sasaki JD, Vacquier VD.
Increased association of synaptosome-associated protein of 25 kDa with syntaxin and vesicle-associated membrane protein following acrosomal exocytosis of sea urchin sperm.
J Biol Chem.    impact factor:   7.666
1998;  273(38): 24355-9

45:  Reverter D, Vendrell J, Canals F, Horstmann J, Aviles FX, Fritz H, Sommerhoff CP.
A carboxypeptidase inhibitor from the medical leech Hirudo medicinalis. Isolation, sequence analysis, cDNA cloning, recombinant expression, and characterization.
J Biol Chem.    impact factor:   7.666
1998;  273(49): 32927-33

46:  Uson I, Sheldrick GM, de La Fortelle E, Bricogne G, Di Marco S, Priestle JP, Grutter MG, Mittl PR.
The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold Des.    impact factor:   7.271
1999;  7(1): 55-63

47:  Salzet M, Salzet-Raveillon B, Cocquerelle C, Verger-Bocquet M, Pryor SC, Rialas CM, Laurent V, Stefano GB.
Leech immunocytes contain proopiomelanocortin: nitric oxide mediates hemolymph proopiomelanocortin processing.
J Immunol.    impact factor:   7.145
1997;  159(11): 5400-11

48:  Brodfuehrer PD, Thorogood MS.
Identified neurons and leech swimming behavior.
Prog Neurobiol.    impact factor:   7.09
2001;  63(4): 371-81

49:  Koh DS, Moody MW, Nguyen TD, Hille B.
Regulation of exocytosis by protein kinases and Ca(2+) in pancreatic duct epithelial cells.
J Gen Physiol.    impact factor:   6.382
2000;  116(4): 507-20

50:  Lu W, Randal M, Kossiakoff A, Kent SB.
Probing intermolecular backbone H-bonding in serine proteinase-protein inhibitor complexes.
Chem Biol.    impact factor:   6.242
1999;  6(7): 419-27

51:  Kang D, Pilon M, Weisblat DA.
Maternal and zygotic expression of a nanos-class gene in the leech Helobdella robusta: primordial germ cells arise from segmental mesoderm.
Dev Biol.    impact factor:   6.049
2002;  245(1): 28-41

52:  Werbrock AH, Meiklejohn DA, Sainz A, Iwasa JH, Savage RM.
A polychaete hunchback ortholog.
Dev Biol.    impact factor:   6.049
2001;  235(2): 476-88

53:  Seaver EC, Shankland M.
Leech segmental repeats develop normally in the absence of signals from either anterior or posterior segments.
Dev Biol.    impact factor:   6.049
2000;  224(2): 339-53

54:  Jellies J, Johansen KM, Johansen J.
Ectopic CNS projections guide peripheral neuron axons along novel pathways in leech embryos.
Dev Biol.    impact factor:   6.049
2000;  218(2): 137-45

55:  Cantillana V, Urrutia M, Ubilla A, Fernandez J.
The complex dynamic network of microtubule and microfilament cytasters of the leech zygote.
Dev Biol.    impact factor:   6.049
2000;  228(1): 136-49

56:  Harik TM, Attaman J, Crowley AE, Jellies J.
Developmentally regulated tissue-associated cues influence axon sprouting and outgrowth and may contribute to target specificity.
Dev Biol.    impact factor:   6.049
1999;  212(2): 351-65

57:  Orii H, Kato K, Umesono Y, Sakurai T, Agata K, Watanabe K.
The planarian HOM/HOX homeobox genes (Plox) expressed along the anteroposterior axis.
Dev Biol.    impact factor:   6.049
1999;  210(2): 456-68

58:  Fay DS, Stanley HM, Han M, Wood WB.
A Caenorhabditis elegans homologue of hunchback is required for late stages of development but not early embryonic patterning.
Dev Biol.    impact factor:   6.049
1999;  205(2): 240-53

59:  Tai MH, Zipser B.
Sequential steps in synaptic targeting of sensory afferents are mediated by constitutive and developmentally regulated glycosylations of CAMs.
Dev Biol.    impact factor:   6.049
1999;  214(2): 258-76

60:  Bruce AE, Shankland M.
Expression of the head gene Lox22-Otx in the leech Helobdella and the origin of the bilaterian body plan.
Dev Biol.    impact factor:   6.049
1998;  201(1): 101-12

61:  Tai MH, Zipser B.
Mannose-specific recognition mediates two aspects of synaptic growth of leech sensory afferents: collateral branching and proliferation of synaptic vesicle clusters.
Dev Biol.    impact factor:   6.049
1998;  201(2): 154-66

62:  Biswas SC, Dutt A, Baker MW, Macagno ER.
Association of LAR-like Receptor Protein Tyrosine Phosphatases with an Enabled Homolog in Hirudo medicinalis.
Mol Cell Neurosci.    impact factor:   5.654
2002;  21(4): 657-70

63:  Green BN, Gotoh T, Suzuki T, Zal F, Lallier FH, Toulmond A, Vinogradov SN.
Observation of large, non-covalent globin subassemblies in the approximately 3600 kDa hexagonal bilayer hemoglobins by electrospray ionization time-of-flight mass spectrometry.
J Mol Biol.    impact factor:   5.501
2001;  309(3): 553-60

64:  Estebanez-Perpina E, Bayes A, Vendrell J, Jongsma MA, Bown DP, Gatehouse JA, Huber R, Bode W, Aviles FX, Reverter D.
Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera.
J Mol Biol.    impact factor:   5.501
2001;  313(3): 629-38

65:  Luo Y, Li SC, Li YT, Luo M.
The 1.8 A structures of leech intramolecular trans-sialidase complexes: evidence of its enzymatic mechanism.
J Mol Biol.    impact factor:   5.501
1999;  285(1): 323-32

66:  Monne M, Hermansson M, von Heijne G.
A turn propensity scale for transmembrane helices.
J Mol Biol.    impact factor:   5.501
1999;  288(1): 141-5

67:  Rester U, Bode W, Moser M, Parry MA, Huber R, Auerswald E.
Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system.
J Mol Biol.    impact factor:   5.501
1999;  293(1): 93-106

68:  Grangeasse C, Doublet P, Vincent C, Vaganay E, Riberty M, Duclos B, Cozzone AJ.
Functional characterization of the low-molecular-mass phosphotyrosine-protein phosphatase of Acinetobacter johnsonii.
J Mol Biol.    impact factor:   5.501
1998;  278(2): 339-47

69:  Rade JJ, Cheung M, Miyamoto S, Dichek DA.
Retroviral vector-mediated expression of hirudin by human vascular endothelial cells: implications for the design of retroviral vectors expressing biologically active proteins.
Gene Ther.    impact factor:   5.237
1999;  6(3): 385-92

70:  Depraetere H, Kerekes A, Deckmyn H.
The collagen-binding leech products rLAPP and calin prevent both von Willebrand factor and alpha2beta1(GPIa/IIa)-I-domain binding to collagen in a different manner.
Thromb Haemost.    impact factor:   4.983
1999;  82(3): 1160-3

71:  Verkleij MW, IJsseldijk MJ, Heijnen-Snyder GJ, Huizinga EG, Morton LF, Knight CG, Sixma JJ, de Groot PG, Barnes MJ.
Adhesive domains in the collagen III fragment alpha1(III)CB4 that support alpha2beta1- and von Willebrand factor-mediated platelet adhesion under flow conditions.
Thromb Haemost.    impact factor:   4.983
1999;  82(3): 1137-44

72:  Faria F, Kelen EM, Sampaio CA, Bon C, Duval N, Chudzinski-Tavassi AM.
A new factor Xa inhibitor (lefaxin) from the Haementeria depressa leech.
Thromb Haemost.    impact factor:   4.983
1999;  82(5): 1469-73

73:  Chudzinski-Tavassi AM, Kelen EM, de Paula Rosa AP, Loyau S, Sampaio CA, Bon C, Angles-Cano E.
Fibrino(geno)lytic properties of purified hementerin, a metalloproteinase from the leech Haementeria depressa.
Thromb Haemost.    impact factor:   4.983
1998;  80(1): 155-60

74:  Salzet M, Capron A, Stefano GB.
Molecular crosstalk in host-parasite relationships: schistosome- and leech-host interactions.
Parasitol Today.    impact factor:   4.94
2000;  16(12): 536-40

75:  Fareed J, Callas D, Hoppensteadt DA, Lewis BE, Bick RL, Walenga JM.
Antithrombin agents as anticoagulants and antithrombotics: implications in drug development.
Semin Hematol.    impact factor:   4.931
1999;  36(1 Suppl 1): 42-56

76:  Gunzel D, Zimmermann F, Durry S, Schlue WR.
Apparent intracellular Mg2+ buffering in neurons of the leech Hirudo medicinalis.
Biophys J.    impact factor:   4.58
2001;  80(3): 1298-310

77:  Richardson JL, Fuentes-Prior P, Sadler JE, Huber R, Bode W.
Characterization of the residues involved in the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor.
Biochemistry.    impact factor:   4.493
2002;  41(8): 2535-42

78:  Hemmi H, Yoshida T, Kumazaki T, Nemoto N, Hasegawa J, Nishioka F, Kyogoku Y, Yokosawa H, Kobayashi Y.
Solution structure of ascidian trypsin inhibitor determined by nuclear magnetic resonance spectroscopy.
Biochemistry.    impact factor:   4.493
2002;  41(34): 10657-64

79:  Lu WY, Starovasnik MA, Dwyer JJ, Kossiakoff AA, Kent SB, Lu W.
Deciphering the role of the electrostatic interactions involving Gly70 in eglin C by total chemical protein synthesis.
Biochemistry.    impact factor:   4.493
2000;  39(13): 3575-84

80:  Martin F, Dimasi N, Volpari C, Perrera C, Di Marco S, Brunetti M, Steinkuhler C, De Francesco R, Sollazzo M.
Design of selective eglin inhibitors of HCV NS3 proteinase.
Biochemistry.    impact factor:   4.493
1998;  37(33): 11459-68

81:  Krezel AM, Ulmer JS, Wagner G, Lazarus RA.
Recombinant decorsin: dynamics of the RGD recognition site.
Protein Sci.    impact factor:   4.457
2000;  9(8): 1428-38

82:  De Filippis V, Russo I, Vindigni A, Di Cera E, Salmaso S, Fontana A.
Incorporation of noncoded amino acids into the N-terminal domain 1-47 of hirudin yields a highly potent and selective thrombin inhibitor.
Protein Sci.    impact factor:   4.457
1999;  8(10): 2213-7

83:  Polverino de Laureto P, Scaramella E, De Filippis V, Marin O, Doni MG, Fontana A.
Chemical synthesis and structural characterization of the RGD-protein decorsin: a potent inhibitor of platelet aggregation.
Protein Sci.    impact factor:   4.457
1998;  7(2): 433-44

84:  Britz FC, Lohr C, Schmidt J, Deitmer JW.
Characterization of a synaptiform transmission between a neuron and a glial cell in the leech central nervous system.
Glia.    impact factor:   4.245
2002;  38(3): 215-27

85:  Deitmer JW, Schneider HP.
Enhancement of glutamate uptake transport by CO(2)/bicarbonate in the leech giant glial cell.
Glia.    impact factor:   4.245
2000;  30(4): 392-400

86:  Muller M, Henrich A, Klockenhoff J, Dierkes PW, Schlue WR.
Effects of ATP and derivatives on neuropile glial cells of the leech central nervous system.
Glia.    impact factor:   4.245
2000;  29(3): 191-201

87:  Deitmer JW, Rose CR, Munsch T, Schmidt J, Nett W, Schneider HP, Lohr C.
Leech giant glial cell: functional role in a simple nervous system.
Glia.    impact factor:   4.245
1999;  28(3): 175-82

88:  Deitmer JW, Kristan WB Jr.
Glial responses during evoked behaviors in the leech.
Glia.    impact factor:   4.245
1999;  26(2): 186-9

89:  Schmidt J, Prinz P, Deitmer JW.
Glial hyperpolarization upon nerve root stimulation in the leech Hirudo medicinalis.
Glia.    impact factor:   4.245
1999;  27(1): 32-8

90:  Lohr C, Deitmer JW.
Dendritic calcium transients in the leech giant glial cell in situ.
Glia.    impact factor:   4.245
1999;  26(2): 109-18

91:  Graf J.
Symbiosis of Aeromonas veronii biovar sobria and Hirudo medicinalis, the medicinal leech: a novel model for digestive tract associations.
Infect Immun.    impact factor:   4.184
1999;  67(1): 1-7

92:  Masino MA, Calabrese RL.
Phase relationships between segmentally organized oscillators in the leech heartbeat pattern generating network.
J Neurophysiol.    impact factor:   3.935
2002;  87(3): 1572-85

93:  Hill AA, Masino MA, Calabrese RL.
Model of intersegmental coordination in the leech heartbeat neuronal network.
J Neurophysiol.    impact factor:   3.935
2002;  87(3): 1586-602

94:  Masino MA, Calabrese RL.
Period differences between segmental oscillators produce intersegmental phase differences in the leech heartbeat timing network.
J Neurophysiol.    impact factor:   3.935
2002;  87(3): 1603-15

95:  Cang J, Friesen WO.
Model for intersegmental coordination of leech swimming: central and sensory mechanisms.
J Neurophysiol.    impact factor:   3.935
2002;  87(6): 2760-9

96:  Burrell BD, Sahley CL, Muller KJ.
Differential effects of serotonin enhance activity of an electrically coupled neural network.
J Neurophysiol.    impact factor:   3.935
2002;  87(6): 2889-95

97:  Scuri R, Mozzachiodi R, Brunelli M.
Activity-Dependent Increase of the AHP Amplitude in T Sensory Neurons of the Leech.
J Neurophysiol.    impact factor:   3.935
2002;  88(5): 2490-500

98:  Mesce KA, Crisp KM, Gilchrist LS.
Mixtures of octopamine and serotonin have nonadditive effects on the CNS of the medicinal leech.
J Neurophysiol.    impact factor:   3.935
2001;  85(5): 2039-46

99:  Friesen WO, Hocker CG.
Functional analyses of the leech swim oscillator.
J Neurophysiol.    impact factor:   3.935
2001;  86(2): 824-35

100:  Baccus SA, Sahley CL, Muller KJ.
Multiple sites of action potential initiation increase neuronal firing rate.
J Neurophysiol.    impact factor:   3.935
2001;  86(3): 1226-36

101:  Wenning A, Erxleben CF, Calabrese RL.
Indirectly gated Cl(-)-dependent Cl(-) channels sense physiological changes of extracellular chloride in the leech.
J Neurophysiol.    impact factor:   3.935
2001;  86(4): 1826-38

102:  Arisi I, Zoccolan D, Torre V.
Distributed motor pattern underlying whole-body shortening in the medicinal leech.
J Neurophysiol.    impact factor:   3.935
2001;  86(5): 2475-88

103:  Baccus SA, Burrell BD, Sahley CL, Muller KJ.
Action potential reflection and failure at axon branch points cause stepwise changes in EPSPs in a neuron essential for learning.
J Neurophysiol.    impact factor:   3.935
2000;  83(3): 1693-700

104:  Wang Y, Strong JA, Sahley CL.
Modulatory effects of myomodulin on the excitability and membrane currents in Retzius cells of the leech.
J Neurophysiol.    impact factor:   3.935
1999;  82(1): 216-25

105:  Shaw BK, Kristan WB Jr.
Relative roles of the S cell network and parallel interneuronal pathways in the whole-body shortening reflex of the medicinal leech.
J Neurophysiol.    impact factor:   3.935
1999;  82(3): 1114-23

106:  Lewis JE, Kristan WB Jr.
Representation of touch location by a population of leech sensory neurons.
J Neurophysiol.    impact factor:   3.935
1998;  80(5): 2584-92

107:  Mozzachiodi R, Scuri R, Roberto M, Brunelli M.
Caulerpenyne, a toxin from the seaweed Caulerpa taxifolia, depresses afterhyperpolarization in invertebrate neurons.
Neuroscience.    impact factor:   3.924
2001;  107(3): 519-26

108:  Weisblat DA, Huang FZ, Isaksen DE, Liu NJ, Chang P.
The other side of the embryo: an appreciation of the non-D quadrants in leech embryos.
Curr Top Dev Biol.    impact factor:   3.914
1999;  46: 105-32

109:  Pellegrini M, Menconi MC, Pellegrino M.
Stretch-activated cation channels of leech neurons exhibit two activity modes.
Eur J Neurosci.    impact factor:   3.899
2001;  13(3): 503-11

110:  Schmidt J, Deitmer JW.
Peptide-mediated glial responses to leydig neuron activity in the leech central nervous system.
Eur J Neurosci.    impact factor:   3.899
1999;  11(9): 3125-33

111:  Calabrese B, Manzi S, Pellegrini M, Pellegrino M.
Stretch-activated cation channels of leech neurons: characterization and role in neurite outgrowth.
Eur J Neurosci.    impact factor:   3.899
1999;  11(7): 2275-84

112:  Schatzthauer R, Fromherz P.
Neuron-silicon junction with voltage-gated ionic currents.
Eur J Neurosci.    impact factor:   3.899
1998;  10(6): 1956-62

113:  De-Miguel FF, Vargas J, Arias C, Escamilla C.
Extracellular matrix glycoproteins inhibit neurite production by cultured neurons.
J Comp Neurol.    impact factor:   3.764
2002;  443(4): 401-11

114:  Crisp KM, Klukas KA, Gilchrist LS, Nartey AJ, Mesce KA.
Distribution and development of dopamine- and octopamine-synthesizing neurons in the medicinal leech.
J Comp Neurol.    impact factor:   3.764
2002;  442(2): 115-29

115:  de Miguel FF, Vargas J.
Native extracellular matrix induces a well-organized bipolar outgrowth pattern with neurite extension and retraction in cultured neurons.
J Comp Neurol.    impact factor:   3.764
2000;  417(4): 387-98

116:  Thorogood MS, Almeida VW, Brodfuehrer PD.
Glutamate receptor 5/6/7-like and glutamate transporter-1-like immunoreactivity in the leech central nervous system.
J Comp Neurol.    impact factor:   3.764
1999;  405(3): 334-44

117:  Reynolds SA, French KA, Baader A, Kristan WB Jr.
Staging of middle and late embryonic development in the medicinal leech, Hirudo medicinalis.
J Comp Neurol.    impact factor:   3.764
1998;  402(2): 155-67

118:  Huang Y, Jellies J, Johansen KM, Johansen J.
Development and pathway formation of peripheral neurons during leech embryogenesis.
J Comp Neurol.    impact factor:   3.764
1998;  397(3): 394-402

119:  Reynolds SA, French KA, Baader A, Kristan WB Jr.
Development of spontaneous and evoked behaviors in the medicinal leech.
J Comp Neurol.    impact factor:   3.764
1998;  402(2): 168-80

120:  Miura Y, Arai T, Ohtake A, Ito M, Yamamoto K, Yamagata T.
Requirement for a different hydrophobic moiety and reliable chromogenic substrate for endo-type glycosylceramidases.
Glycobiology.    impact factor:   3.728
1999;  9(9): 957-60

121:  Emes RD, Wang WZ, Lanary K, Blackshaw SE.
HmCRIP, a cysteine-rich intestinal protein, is expressed by an identified regenerating nerve cell.
FEBS Lett.    impact factor:   3.72
2003;  533(1): 124-8

122:  Salzet M.
Anticoagulants and inhibitors of platelet aggregation derived from leeches.
FEBS Lett.    impact factor:   3.72
2001;  492(3): 187-92

123:  Tanaka AS, Silva MM, Torquato RJ, Noguti MA, Sampaio CA, Fritz H, Auerswald EA.
Functional phage display of leech-derived tryptase inhibitor (LDTI): construction of a library and selection of thrombin inhibitors.
FEBS Lett.    impact factor:   3.72
1999;  458(1): 11-6

124:  Bachali S, Jager M, Hassanin A, Schoentgen F, Jolles P, Fiala-Medioni A, Deutsch JS.
Phylogenetic analysis of invertebrate lysozymes and the evolution of lysozyme function.
J Mol Evol.    impact factor:   3.655
2002;  54(5): 652-64

125:  Kikuchi Y, Fukatsu T.
Endosymbiotic bacteria in the esophageal organ of glossiphoniid leeches.
Appl Environ Microbiol.    impact factor:   3.541
2002;  68(9): 4637-41

126:  Kikuchi Y, Sameshima S, Kitade O, Kojima J, Fukatsu T.
Novel clade of Rickettsia spp. from leeches.
Appl Environ Microbiol.    impact factor:   3.541
2002;  68(2): 999-1004

127:  Indergand S, Graf J.
Ingested blood contributes to the specificity of the symbiosis of Aeromonas veronii biovar sobria and Hirudo medicinalis, the medicinal leech.
Appl Environ Microbiol.    impact factor:   3.541
2000;  66(11): 4735-41

128:  Chen D, Riesbeck K, McVey JH, Kemball-Cook G, Tuddenham EG, Lechler RI, Dorling A.
Regulated inhibition of coagulation by porcine endothelial cells expressing P-selectin-tagged hirudin and tissue factor pathway inhibitor fusion proteins.
Transplantation.    impact factor:   3.463
1999;  68(6): 832-9

129:  Chen D, Riesbeck K, Kemball-Cook G, McVey JH, Tuddenham EG, Lechler RI, Dorling A.
Inhibition of tissue factor-dependent and -independent coagulation by cell surface expression of novel anticoagulant fusion proteins.
Transplantation.    impact factor:   3.463
1999;  67(3): 467-74

130:  Beck A, Lohr C, Berthold H, Deitmer JW.
Calcium influx into dendrites of the leech Retzius neuron evoked by 5-hydroxytryptamine.
Cell Calcium.    impact factor:   3.438
2002;  31(3): 137-49

131:  Ukhanov K, Mills SJ, Potter BV, Walz B.
InsP(3)-induced Ca(2+) release in permeabilized invertebrate photoreceptors: a link between phototransduction and Ca(2+) stores.
Cell Calcium.    impact factor:   3.438
2001;  29(5): 335-45

132:  Schoppe J, Hochstrate P, Schlue WR.
Caffeine mediates cation influx and intracellular Ca2+ release in leech P neurones.
Cell Calcium.    impact factor:   3.438
1997;  22(5): 385-97

133:  Pinato G, Parodi P, Bisso A, Macri D, Kawana A, Jimbo Y, Torre V.
Properties of the evoked spatio-temporal electrical activity in neuronal assemblies.
Rev Neurosci.    impact factor:   3.387
1999;  10(3-4): 279-90

134:  Erba F, Fiorucci L, Sommerhoff CP, Coletta M, Ascoli F.
Kinetic and thermodynamic analysis of leech-derived tryptase inhibitor interaction with bovine tryptase and bovine trypsin.
Biol Chem.    impact factor:   3.356
2000;  381(11): 1117-22

135:  Ascenzi P, Bolognesi M, Catalucci D, Pascarella S, Ruoppolo M, Rizzi M.
Leech antihemostatic proteins share the T-knot scaffold, a disulfide-reinforced structural motif.
Biol Chem.    impact factor:   3.356
1998;  379(11): 1387-9

136:  de-Miguel FF, Vargas J.
Steps in the formation of a bipolar outgrowth pattern by cultured neurons, and their substrate dependence.
J Neurobiol.    impact factor:   3.33
2002;  50(2): 106-17

137:  Beck A, Lohr C, Deitmer JW.
Calcium transients in subcompartments of the leech Retzius neuron as induced by single action potentials.
J Neurobiol.    impact factor:   3.33
2001;  48(1): 1-18

138:  Li Y, Perruccio E, Zhang X, Kleinhaus AL.
Bitter substances suppress afferent responses to an appetitive mixture: evidence for peripheral integration of chemosensory stimuli.
J Neurobiol.    impact factor:   3.33
2001;  49(4): 255-63

139:  Baker MW, Macagno ER.
The role of a LAR-like receptor tyrosine phosphatase in growth cone collapse and mutual-avoidance by sibling processes.
J Neurobiol.    impact factor:   3.33
2000;  44(2): 194-203

140:  Baker MW, Rauth SJ, Macagno ER.
Possible role of the receptor protein tyrosine phosphatase HmLAR2 in interbranch repulsion in a leech embryonic cell.
J Neurobiol.    impact factor:   3.33
2000;  45(1): 47-60

141:  Wu X, Ritter B, Schlattjan JH, Lessmann V, Heumann R, Dietzel ID.
Protein expression patterns of identified neurons and of sprouting cells from the leech central nervous system.
J Neurobiol.    impact factor:   3.33
2000;  44(3): 320-32

142:  Johnson LA, Kristan WB, Jellies J, French KA.
Disruption of peripheral target contact influences the development of identified central dendritic branches in a leech motor neuron in vivo.
J Neurobiol.    impact factor:   3.33
2000;  43(4): 365-78

143:  Zhang X, Wilson RJ, Li Y, Kleinhaus AL.
Chemical and thermal stimuli have short-lived effects on the retzius cell in the medicinal leech.
J Neurobiol.    impact factor:   3.33
2000;  43(3): 304-11

144:  Gan WB, Wong VY, Phillips A, Ma C, Gershon TR, Macagno ER.
Cellular expression of a leech netrin suggests roles in the formation of longitudinal nerve tracts and in regional innervation of peripheral targets.
J Neurobiol.    impact factor:   3.33
1999;  40(1): 103-15

145:  Xu Y, Bolton B, Zipser B, Jellies J, Johansen KM, Johansen J.
Gliarin and macrolin, two novel intermediate filament proteins specifically expressed in sets and subsets of glial cells in leech central nervous system.
J Neurobiol.    impact factor:   3.33
1999;  40(2): 244-53

146:  Weiss JL, Yang J, Jie C, Walker DL, Ahmed S, Zhu Y, Huang Y, Johansen KM, Johansen J.
Molecular cloning and characterization of LKv1, a novel voltage-gated potassium channel in leech.
J Neurobiol.    impact factor:   3.33
1999;  38(2): 287-99

147:  Wang H, Macagno ER.
A detached branch stops being recognized as self by other branches of a neuron.
J Neurobiol.    impact factor:   3.33
1998;  35(1): 53-64

148:  Becker TS, Bothe G, Harley AR, Macagno ER.
Cell proliferation in a peripheral target is required for the induction of central neurogenesis in the leech.
J Neurobiol.    impact factor:   3.33
1998;  34(4): 295-303

149:  French KA, Murphy JA, Szczupak L.
Target tissues affect cellular properties of cocultured leech Retzius neurons.
J Neurobiol.    impact factor:   3.33
1998;  34(1): 55-68

150:  Bi Q, Cen X, Huang Y, Zhu S.
Construction and characterization of trifunctional single-chain urokinase-type plasminogen activators.
Eur J Biochem.    impact factor:   3.307
2002;  269(6): 1708-13

151:  Laurent V, Salzet B, Verger-Bocquet M, Bernet F, Salzet M.
Morphine-like substance in leech ganglia. Evidence and immune modulation.
Eur J Biochem.    impact factor:   3.307
2000;  267(8): 2354-61

152:  Ito Y, Yoshikawa A, Hotani T, Fukuda S, Sugimura K, Imoto T.
Amino acid sequences of lysozymes newly purified from invertebrates imply wide distribution of a novel class in the lysozyme family.
Eur J Biochem.    impact factor:   3.307
1999;  259(1-2): 456-61

153:  Kim DR, Kang KW.
Amino acid sequence of piguamerin, an antistasin-type protease inhibitor from the blood sucking leech Hirudo nipponia.
Eur J Biochem.    impact factor:   3.307
1998;  254(3): 692-7

154:  Chopin V, Matias I, Stefano GB, Salzet M.
Amino acid sequence determination and biological activity of therin, a naturally occuring specific trypsin inhibitor from the leech Theromyzon tessulatum.
Eur J Biochem.    impact factor:   3.307
1998;  254(3): 565-70

155:  Bergwerff AA, Stark W, Fendrich G, Knecht R, Blommers MJ, Maerki W, Kragten EA, van Oostrum J.
Identification of Man alpha1-3Man alpha1-2Man and Man-linked phosphate on O-mannosylated recombinant leech-derived tryptase inhibitor produced by Saccharomyces cerevisiae and determination of the solution conformation of the mannosylated polypeptide.
Eur J Biochem.    impact factor:   3.307
1998;  253(3): 560-75

156:  Chopin V, Stefano GB, Salzet M.
Amino-acid-sequence determination and biological activity of tessulin, a naturally occurring trypsin-chymotrypsin inhibitor isolated from the leech Theromyzon tessulatum.
Eur J Biochem.    impact factor:   3.307
1998;  258(2): 662-8

157:  Moser M, Auerswald E, Mentele R, Eckerskorn C, Fritz H, Fink E.
Bdellastasin, a serine protease inhibitor of the antistasin family from the medical leech (Hirudo medicinalis)--primary structure, expression in yeast, and characterisation of native and recombinant inhibitor.
Eur J Biochem.    impact factor:   3.307
1998;  253(1): 212-20

158:  Friedrich T, Kroger B, Koerwer W, Strube KH, Meyer T, Bialojan S.
An isopeptide bond splitting enzyme from Hirudo medicinalis similar to gamma-glutamyl transpeptidase.
Eur J Biochem.    impact factor:   3.307
1998;  256(2): 297-302

159:  Fischer BE, Schlokat U, Himmelspach M, Dorner F.
Binding of hirudin to meizothrombin.
Protein Eng.    impact factor:   3.209
1998;  11(8): 715-21

160:  Sartor C, Limouzin-Perotti F, Legre R, Casanova D, Bongrand MC, Sambuc R, Drancourt M.
Nosocomial Infections with Aeromonas hydrophila from Leeches.
Clin Infect Dis.    impact factor:   3.199
2002;  35(1): E1-5

161:  Siddall ME, Apakupakul K, Burreson EM, Coates KA, Erseus C, Gelder SR, Kallersjo M, Trapido-Rosenthal H.
Validating Livanow: molecular data agree that leeches, Branchiobdellidans, and Acanthobdella peledina form a monophyletic group of oligochaetes.
Mol Phylogenet Evol.    impact factor:   3.127
2001;  21(3): 346-51

162:  Martin P, Kaygorodova I, Sherbakov DY, Verheyen E.
Rapidly evolving lineages impede the resolution of phylogenetic relationships among Clitellata (Annelida).
Mol Phylogenet Evol.    impact factor:   3.127
2000;  15(3): 355-68

163:  Apakupakul K, Siddall ME, Burreson EM.
Higher level relationships of leeches (Annelida: Clitellata: Euhirudinea) based on morphology and gene sequences.
Mol Phylogenet Evol.    impact factor:   3.127
1999;  12(3): 350-9

164:  Kojima S.
Paraphyletic status of Polychaeta suggested by phylogenetic analysis based on the amino acid sequences of elongation factor-1 alpha.
Mol Phylogenet Evol.    impact factor:   3.127
1998;  9(2): 255-61

165:  Siddall ME, Burreson EM.
Phylogeny of leeches (Hirudinea) based on mitochondrial cytochrome c oxidase subunit I.
Mol Phylogenet Evol.    impact factor:   3.127
1998;  9(1): 156-62

166:  Meis S, Deitmer JW.
Developmental changes of potassium currents of embryonic leech ganglion cells in primary culture.
J Neurosci Res.    impact factor:   3.126
1997;  50(6): 967-78

167:  Cruz CP, Eidt J, Drouilhet J, Brown AT, Wang Y, Barnes CS, Moursi MM.
Saratin, an inhibitor of von Willebrand factor-dependent platelet adhesion, decreases platelet aggregation and intimal hyperplasia in a rat carotid endarterectomy model.
J Vasc Surg.    impact factor:   3.114
2001;  34(4): 724-9

168:  Hochstrate P, Dierkes PW, Kilb W, Schlue WR.
Modulation of Ca2+ influx in leech Retzius neurons II. Effect of extracellular Ca2+.
J Membr Biol.    impact factor:   2.973
2001;  184(1): 27-33

169:  Hochstrate P, Dierkes PW, Kilb W, Schlue WR.
Modulation of Ca2+ influx in leech Retzius neurons. I. Effect of extracellular pH.
J Membr Biol.    impact factor:   2.973
2001;  184(1): 13-25

170:  Menconi MC, Pellegrini M, Pellegrino M.
Voltage-induced activation of mechanosensitive cation channels of leech neurons.
J Membr Biol.    impact factor:   2.973
2001;  180(1): 65-72

171:  Kravetz RE.
Leech jar.
Am J Gastroenterol.    impact factor:   2.945
2001;  96(3): 894

172:  Raj SM, Radzi M, Tee MH.
Severe rectal bleeding due to leech bite.
Am J Gastroenterol.    impact factor:   2.945
2000;  95(6): 1607

173:  Feinsod M.
Leeches for the unfortunate locksmith: self-inflicted posttraumatic transient cerebral blindness--mode of treatment and underlying mechanism (1826).
Neurosurgery.    impact factor:   2.821
2001;  48(3): 660-3

174:  Wilson RJ, Kleinhaus AL.
Segmental control of midbody peristalsis during the consummatory phase of feeding in the medicinal leech, Hirudo medicinalis.
Behav Neurosci.    impact factor:   2.719
2000;  114(3): 635-46

175:  Lohr C, Beck A, Deitmer JW.
Activity-dependent accumulation of Ca2+ in axon and dendrites of the leech Leydig neuron.
Neuroreport.    impact factor:   2.682
2001;  12(17): 3649-53

176:  Schnizler M, Krumm S, Clauss W.
Annelid epithelia as models for electrogenic Na(+) transport.
Biochim Biophys Acta.    impact factor:   2.59
2002;  1566(1-2): 84-91

177:  Ji Y, Schroeder D, Byrne D, Zipser B, Jellies J, Johansen KM, Johansen J.
Molecular identification and sequence analysis of Hillarin, a novel protein localized at the axon hillock.
Biochim Biophys Acta.    impact factor:   2.59
2001;  1519(3): 246-9

178:  Coutte L, Slomianny MC, Malecha J, Baert JL.
Cloning and expression analysis of a cDNA that encodes a leech hemerythrin.
Biochim Biophys Acta.    impact factor:   2.59
2001;  1518(3): 282-6

179:  Jie C, Xu Y, Wang D, Lukin D, Zipser B, Jellies J, Johansen KM, Johansen J.
Posttranslational processing and differential glycosylation of Tractin, an Ig-superfamily member involved in regulation of axonal outgrowth.
Biochim Biophys Acta.    impact factor:   2.59
2000;  1479(1-2): 1-14

180:  Sommerhoff CP, Bode W, Matschiner G, Bergner A, Fritz H.
The human mast cell tryptase tetramer: a fascinating riddle solved by structure.
Biochim Biophys Acta.    impact factor:   2.59
2000;  1477(1-2): 75-89

181:  Zavalova LL, Baskova IP, Lukyanov SA, Sass AV, Snezhkov EV, Akopov SB, Artamonova II, Archipova VS, Nesmeyanov VA, Kozlov DG, Benevolensky SV, Kiseleva VI, Poverenny AM, Sverdlov ED.
Destabilase from the medicinal leech is a representative of a novel family of lysozymes.
Biochim Biophys Acta.    impact factor:   2.59
2000;  1478(1): 69-77

182:  Jie C, Zipser B, Jellies J, Johansen KM, Johansen J.
Differential glycosylation and proteolytical processing of LeechCAM in central and peripheral leech neurons.
Biochim Biophys Acta.    impact factor:   2.59
1999;  1452(2): 161-71

183:  Cho JH, Park CB, Yoon YG, Kim SC.
Lumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization.
Biochim Biophys Acta.    impact factor:   2.59
1998;  1408(1): 67-76

184:  Salzet M.
Leech thrombin inhibitors.
Curr Pharm Des.    impact factor:   2.569
2002;  8(7): 493-503

185:  Schoofs L, Clynen E, Salzet M.
Trypsin and chymotrypsin inhibitors in insects and gut leeches.
Curr Pharm Des.    impact factor:   2.569
2002;  8(7): 483-91

186:  Donges R, Brazel D.
Determination of recombinant hirudin structural deviants by capillary zone electrophoresis augmented with buffer additives.
J Chromatogr A.    impact factor:   2.52
2002;  979(1-2): 217-26

187:  Pandey CK, Sharma R, Baronia A, Agarwal A, Singh N.
An unusual cause of respiratory distress: live leech in the larynx.
Anesth Analg.    impact factor:   2.509
2000;  90(5): 1227-8

188:  Nagahama T, Ukena K, Oumi T, Morishita F, Furukawa Y, Matsushima O, Satake H, Takuwa K, Kawano T, Minakata H, Nomoto K.
Localization of leech excitatory peptide, a member of the GGNG peptides, in the central nervous system of a leech (Whitmania pigra) by immunohistochemistry and in situ hybridization.
Cell Tissue Res.    impact factor:   2.488
1999;  297(1): 155-62

189:  Aschenbrenner S, Walz B.
Pleated septate junctions in leech photoreceptors: ultrastructure, arrangement of septa, gate and fence functions.
Cell Tissue Res.    impact factor:   2.488
1998;  293(2): 253-69

190:  Rovner ES, Ginsberg DA, Raz S.
Re: Female Stress Urinary Incontinence Clinical Guidelines Panel summary report on surgical management of female stress urinary incontinence.
J Urol.    impact factor:   2.486
1998;  159(5): 1646-7

191:  Pantuck AJ.
Re: leech therapy for massive scrotal hematoma following percutaneous transluminal angioplasty.
J Urol.    impact factor:   2.486
1998;  159(5): 1647-8

192:  Haas CJ, Zink A, Palfi G, Szeimies U, Nerlich AG.
Detection of leprosy in ancient human skeletal remains by molecular identification of Mycobacterium leprae.
Am J Clin Pathol.    impact factor:   2.425
2000;  114(3): 428-36

193:  Nowak G.
Pharmacology of recombinant hirudin.
Semin Thromb Hemost.    impact factor:   2.385
2002;  28(5): 415-24

194:  Markwardt F.
Hirudin as alternative anticoagulant--a historical review.
Semin Thromb Hemost.    impact factor:   2.385
2002;  28(5): 405-14

195:  Barnes CS, Krafft B, Frech M, Hofmann UR, Papendieck A, Dahlems U, Gellissen G, Hoylaerts MF.
Production and characterization of saratin, an inhibitor of von Willebrand factor-dependent platelet adhesion to collagen.
Semin Thromb Hemost.    impact factor:   2.385
2001;  27(4): 337-48

196:  Menssen HD, Brandt N, Leben R, Muller F, Thiel E, Melber K.
Measurement of hematological, clinical chemistry, and infection parameters from hirudinized blood collected in universal blood sampling tubes.
Semin Thromb Hemost.    impact factor:   2.385
2001;  27(4): 349-56

197:  Turpie AG.
Anticoagulants in acute coronary syndromes.
Am J Cardiol.    impact factor:   2.361
1999;  84(5A): 2M-6M

198:  Fox KA.
Implications of the Organization to Assess Strategies for Ischemic Syndromes-2 (OASIS-2) study and the results in the context of other trials.
Am J Cardiol.    impact factor:   2.361
1999;  84(5A): 26M-31M

199:  Schnizler M, Buss M, Clauss W.
Effects of extracellular purines on ion transport across the integument of Hirudo medicinalis.
J Exp Biol.    impact factor:   2.354
2002;  205(Pt 17): 2705-13

200:  De-Miguel FF, Vargas-Caballero M, Garcia-Perez E.
Spread of synaptic potentials through electrical synapses in Retzius neurones of the leech.
J Exp Biol.    impact factor:   2.354
2001;  204(Pt 19): 3241-50

201:  Milde H, Weber WM, Salzet M, Clauss W.
Regulation of Na(+) transport across leech skin by peptide hormones and neurotransmitters.
J Exp Biol.    impact factor:   2.354
2001;  204(Pt 8): 1509-17

202:  Bernhardi RV, Nicholls JG.
Transformation of leech microglial cell morphology and properties following co-culture with injured central nervous system tissue
J Exp Biol.    impact factor:   2.354
1999;  202 (Pt 6): 723-8

203:  Szczupak L, Edgar J, Peralta ML, Kristan WB.
Long-lasting depolarization of leech neurons mediated by receptors with a nicotinic binding site
J Exp Biol.    impact factor:   2.354
1998;  201 (Pt 12): 1895-906

204:  Szczupak L, Edgar J, Peralta ML, Kristan WB Jr.
Long-lasting depolarization of leech neurons mediated by receptors with a nicotinic binding site.
J Exp Biol.    impact factor:   2.354
1998;  201 ( Pt 12): 1895-906

205:  Burgin AM, Szczupak L.
Basal acetylcholine release in leech ganglia depolarizes neurons through receptors with a nicotinic binding site
J Exp Biol.    impact factor:   2.354
1998;  201 (Pt 12): 1907-15

206:  Marin Burgin A, Szczupak L.
Basal acetylcholine release in leech ganglia depolarizes neurons through receptors with a nicotinic binding site.
J Exp Biol.    impact factor:   2.354
1998;  201 ( Pt 12): 1907-15

207:  Calabrese RL.
The roles of endogenous membrane properties and synaptic interaction in generating the heartbeat rhythm of the leech, Hirudo medicinalis.
J Exp Biol.    impact factor:   2.354
1979;  82: 163-76

208:  Bruns D.
Serotonin transport in cultured leech neurons.
Methods Enzymol.    impact factor:   2.34
1998;  296: 593-607

209:  Waldner JC, Lahr SJ, Edgell MH, Pielak GJ.
Nonideality and protein thermal denaturation.
Biopolymers.    impact factor:   2.331
1999;  49(6): 471-9

210:  Lombardi A, De Simone G, Galdiero S, Staiano N, Nastri F, Pavone V.
From natural to synthetic multisite thrombin inhibitors.
Biopolymers.    impact factor:   2.331
1999;  51(1): 19-39

211:  Zaccardi ML, Traina G, Cataldo E, Brunelli M.
Nonassociative learning in the leech Hirudo medicinalis.
Behav Brain Res.    impact factor:   2.318
2001;  126(1-2): 81-92

212:  Misell LM, Shaw BK, Kristan WB Jr.
Behavioral hierarchy in the medicinal leech, Hirudo medicinalis: feeding as a dominant behavior.
Behav Brain Res.    impact factor:   2.318
1998;  90(1): 13-21

213:  Hochstrate P, Schlue WR.
The ouabain-induced [Ca2+]i increase in leech Retzius neurones is mediated by voltage-dependent Ca2+ channels.
Brain Res.    impact factor:   2.302
2001;  892(2): 248-54

214:  Kilb W, Schlue WR.
Mechanism of the kainate-induced intracellular acidification in leech Retzius neurons.
Brain Res.    impact factor:   2.302
1999;  824(2): 168-82

215:  Muller M, Dierkes PW, Schlue WR.
Ionic mechanism of 4-aminopyridine action on leech neuropile glial cells.
Brain Res.    impact factor:   2.302
1999;  826(1): 63-73

216:  Frey G, Lucht M, Schlue WR.
ATP-inhibited K+ channels and membrane potential of identified leech neurons.
Brain Res.    impact factor:   2.302
1998;  798(1-2): 247-53

217:  Stefano GB, Rialas CM, Deutsch DG, Salzet M.
Anandamide amidase inhibition enhances anandamide-stimulated nitric oxide release in invertebrate neural tissues.
Brain Res.    impact factor:   2.302
1998;  793(1-2): 341-5

218:  Muller M, Schlue WR.
Macroscopic and single-channel chloride currents in neuropile glial cells of the leech central nervous system.
Brain Res.    impact factor:   2.302
1998;  781(1-2): 307-19

219:  Elphick MR.
An invertebrate G-protein coupled receptor is a chimeric cannabinoid/melanocortin receptor
Brain Res.    impact factor:   2.302
1998;  780(1): 168-71

220:  Elphick MR.
An invertebrate G-protein coupled receptor is a chimeric cannabinoid/melanocortin receptor.
Brain Res.    impact factor:   2.302
1998;  780(1): 170-3

221:  Hill AA, Lu J, Masino MA, Olsen OH, Calabrese RL.
A model of a segmental oscillator in the leech heartbeat neuronal network.
J Comput Neurosci.    impact factor:   2.286
2001;  10(3): 281-302

222:  Shimizu T, Savage RM.
Expression of hunchback protein in a subset of ectodermal teloblasts of the oligochaete annelid Tubifex.
Dev Genes Evol.    impact factor:   2.269
2002;  212(11): 520-5

223:  Goldstein B, Leviten MW, Weisblat DA.
Dorsal and snail homologs in leech development.
Dev Genes Evol.    impact factor:   2.269
2001;  211(7): 329-37

224:  Aisemberg GO, Kuhn J, Macagno ER.
Netrin signal is produced in leech embryos by segmentally iterated sets of central neurons and longitudinal muscle cells.
Dev Genes Evol.    impact factor:   2.269
2001;  211(12): 589-96

225:  Iwasa JH, Suver DW, Savage RM.
The leech hunchback protein is expressed in the epithelium and CNS but not in the segmental precursor lineages.
Dev Genes Evol.    impact factor:   2.269
2000;  210(6): 277-88

226:  Tsubokawa R, Wedeen CJ.
Cell death in late embryogenesis of the leech Helobdella.
Dev Genes Evol.    impact factor:   2.269
1999;  209(9): 515-25

227:  Desjeux I, Price DJ.
The production and elimination of supernumerary blast cells in the leech embryo.
Dev Genes Evol.    impact factor:   2.269
1999;  209(5): 284-93

228:  Shain DH, Ramirez-Weber FA, Hsu J, Weisblat DA.
Gangliogenesis in leech: morphogenetic processes leading to segmentation in the central nervous system.
Dev Genes Evol.    impact factor:   2.269
1998;  208(1): 28-36

229:  Wong VY, Macagno ER.
Lox6, a leech Dfd ortholog, is expressed in the central nervous system and in peripheral sensory structures.
Dev Genes Evol.    impact factor:   2.269
1998;  208(1): 51-5

230:  Liu NL, Isaksen DE, Smith CM, Weisblat DA.
Movements and stepwise fusion of endodermal precursor cells in leech.
Dev Genes Evol.    impact factor:   2.269
1998;  208(3): 117-27

231:  Castanon I, Baylies MK.
A Twist in fate: evolutionary comparison of Twist structure and function.
Gene.    impact factor:   2.258
2002;  287(1-2): 11-22

232:  Fedorov A, Johnston H, Korneev S, Blackshaw S, Davies J.
Cloning, characterisation and expression of the alpha-tubulin genes of the leech, Hirudo medicinalis.
Gene.    impact factor:   2.258
1999;  227(1): 11-9

233:  Matsushima O, Takahama H, Ono Y, Nagahama T, Morishita F, Furukawa Y, Iwakoshi-Ukena E, Hisada M, Takuwa-Kuroda K, Minakata H.
A novel GGNG-related neuropeptide from the polychaete Perinereis vancaurica.
Peptides.    impact factor:   2.173
2002;  23(8): 1379-90

234:  Wang Y, Price DA, Sahley CL.
Identification and characterization of a myomodulin-like peptide in the leech.
Peptides.    impact factor:   2.173
1998;  19(3): 487-93

235:  Cellucci CJ, Brodfuehrer PD, Acera-Pozzi R, Dobrovolny H, Engler E, Los J, Thompson R, Albano AM.
Linear and nonlinear measures predict swimming in the leech
Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics.    impact factor:   2.142
2000;  62(4 Pt A): 4826-34

236:  Movassaghi G.
Re: The leech and the physician.
World J Surg.    impact factor:   2.025
2001;  25(4): 532-3

237:  Mory RN, Mindell D, Bloom DA.
The leech and the physician: biology, etymology, and medical practice with Hirudinea medicinalis.
World J Surg.    impact factor:   2.025
2000;  24(7): 878-83

238:  Shan D, Zhang RJ.
Frequency coding of positional information by an identified neuron, the AP cell, in the leech, Whitmania pigra.
Brain Res Bull.    impact factor:   1.977
2001;  56(6): 511-5

239:  Kristan WB Jr, Eisenhart FJ, Johnson LA, French KA.
Development of neuronal circuits and behaviors in the medicinal leech.
Brain Res Bull.    impact factor:   1.977
2000;  53(5): 561-70

240:  Michalsen A, Deuse U, Esch T, Dobos G, Moebus S.
Effect of leeches therapy (Hirudo medicinalis) in painful osteoarthritis of the knee: a pilot study.
Ann Rheum Dis.    impact factor:   1.968
2001;  60(10): 986

241:  Gladwell TD.
Bivalirudin: a direct thrombin inhibitor.
Clin Ther.    impact factor:   1.955
2002;  24(1): 38-58

242:  Pini M.
Future prospects of prophylaxis for deep vein thrombosis.
Blood Coagul Fibrinolysis.    impact factor:   1.938
1999;  10 Suppl 2: S19-27

243:  Arocha-Pinango CL, Marchi R, Carvajal Z, Guerrero B.
Invertebrate compounds acting on the hemostatic mechanism.
Blood Coagul Fibrinolysis.    impact factor:   1.938
1999;  10(2): 43-68

244:  Smolle J, Cerroni L, Kerl H.
Multiple pseudolymphomas caused by Hirudo medicinalis therapy.
J Am Acad Dermatol.    impact factor:   1.905
2000;  43(5 Pt 1): 867-9

245:  Grutter AS.
Cleaning symbioses from the parasites' perspective.
Parasitology.    impact factor:   1.868
2002;  124 Suppl: S65-81

246:  Valtonen ET, Pulkkinen K, Poulin R, Julkunen M.
The structure of parasite component communities in brackish water fishes of the northeastern Baltic Sea.
Parasitology.    impact factor:   1.868
2001;  122(Pt 4): 471-81

247:  Kearn GC.
The survival of monogenean (platyhelminth) parasites on fish skin.
Parasitology.    impact factor:   1.868
1999;  119 Suppl: S57-88

248:  Pinato G, Torre V.
Coding and adaptation during mechanical stimulation in the leech nervous system.
J Physiol.    impact factor:   1.773
2000;  529 Pt 3: 747-62

249:  Deitmer JW, Schneider HP.
Acid/base transport across the leech giant glial cell membrane at low external bicarbonate concentration.
J Physiol.    impact factor:   1.773
1998;  512 ( Pt 2): 459-69

250:  Nett W, Deitmer JW.
Intracellular Ca2+ regulation by the leech giant glial cell.
J Physiol.    impact factor:   1.773
1998;  507 ( Pt 1): 147-62

251:  Ali DW, Catarsi S, Drapeau P.
Ionotropic and metabotropic activation of a neuronal chloride channel by serotonin and dopamine in the leech Hirudo medicinalis.
J Physiol.    impact factor:   1.773
1998;  509 ( Pt 1): 211-9

252:  Scott D, Coleman PJ, Abiona A, Ashhurst DE, Mason RM, Levick JR.
Effect of depletion of glycosaminoglycans and non-collagenous proteins on interstitial hydraulic permeability in rabbit synovium.
J Physiol.    impact factor:   1.773
1998;  511 ( Pt 2): 629-43

253:  Coleman PJ, Scott D, Abiona A, Ashhurst DE, Mason RM, Levick JR.
Effect of depletion of interstitial hyaluronan on hydraulic conductance in rabbit knee synovium.
J Physiol.    impact factor:   1.773
1998;  509 ( Pt 3): 695-710

254:  Auw-Haedrich C, Keim A, Kist M.
Conjunctival infestation of a child with Theromyzon tessulatum.
Br J Ophthalmol.    impact factor:   1.759
1998;  82(9): 1093-4

255:  Grossman MD, Karlovitz A.
Lingual trauma: the use of medicinal leeches in the treatment of massive lingual hematoma.
J Trauma.    impact factor:   1.752
1998;  44(6): 1083-5

256:  Fernandez J, Olea N, Ubilla A, Cantillana V.
Formation of polar cytoplasmic domains (teloplasms) in the leech egg is a three-step segregation process.
Int J Dev Biol.    impact factor:   1.743
1998;  42(2): 149-62

257:  Fernandez J, Roegiers F, Cantillana V, Sardet C.
Formation and localization of cytoplasmic domains in leech and ascidian zygotes.
Int J Dev Biol.    impact factor:   1.743
1998;  42(8): 1075-84

258:  Wedeen CJ, Figueroa NB.
Expression of actin mRNA in embryos of the leech Helobdella triserialis.
Int J Dev Biol.    impact factor:   1.743
1998;  42(4): 581-90

259:  Chopin V, Stefano G, Salzet M.
Biochemical evidence of specific trypsin-chymotrypsin inhibitors in the rhynchobdellid leech, Theromyzon tessulatum.
J Enzyme Inhib.    impact factor:   1.733
2000;  15(4): 367-79

260:  Vitturi R, Libertini A, Armetta F, Sparacino L, Colomba MS.
Chromosome analysis and FISH mapping of ribosomal DNA (rDNA), telomeric (TTAGGG)n and (GATA)n repeats in the leech Haemopis sanguisuga (L.) (Annelida: Hirudinea).
Genetica.    impact factor:   1.699
2002;  115(2): 189-94

261:  Wisenden BD, Pohlman SG, Watkin EE.
Avoidance of conspecific injury-released chemical cues by free-ranging Gammarus lacustris (Crustacea:Amphipoda).
J Chem Ecol.    impact factor:   1.653
2001;  27(6): 1249-58

262:  Liu G, Mu SF, Yun LH, Ding ZK, Sun MJ.
Systematic study of the substituted active C-terminus of hirudin.
J Pept Res.    impact factor:   1.638
1999;  54(6): 480-90

263:  Abo S, Ciccotosto S, Alafaci A, von Itzstein M.
The synthesis and evaluation of novel sialic acid analogues bound to matrices for the purification of sialic acid-recognising proteins.
Carbohydr Res.    impact factor:   1.606
1999;  322(3-4): 201-8

264:  Zipser B, Bradford JJ, Hollingsworth RI.
Structural analysis of leech galactocerebrosides using 1D and 2D NMR spectroscopy, gas chromatography-mass spectrometry, and FAB mass spectrometry.
Carbohydr Res.    impact factor:   1.606
1998;  308(1-2): 47-55

265:  Kim KY, Lim HK, Lee KJ, Park DH, Kang KW, Chung SI, Jung KH.
Production and characterization of recombinant guamerin, an elastase-specific inhibitor, in the methylotrophic yeast Pichia pastoris.
Protein Expr Purif.    impact factor:   1.569
2000;  20(1): 1-9

266:  Hong SJ, Kang KW.
Purification of granulin-like polypeptide from the blood-sucking leech, Hirudo nipponia.
Protein Expr Purif.    impact factor:   1.569
1999;  16(2): 340-6

267:  Stefano GB, Salzet-Raveillon B, Salzet M.
Mytilus edulis hemolymph contain prodynorphin.
Immunol Lett.    impact factor:   1.494
1998;  63(1): 33-9

268:  Siddall ME, Desser SS.
Transmission of Haemogregarina balli from painted turtles to snapping turtles through the leech Placobdella ornata.
J Parasitol.    impact factor:   1.485
2001;  87(5): 1217-8

269:  Zintl A, Voorheis HP, Holland CV.
Experimental infections of farmed eels with different Trypanosoma granulosum life-cycle stages and investigation of pleomorphism.
J Parasitol.    impact factor:   1.485
2000;  86(1): 56-9

270:  Burreson EM, Kearn GC.
Rhopalobdella japonica n. gen., n. sp. (Hirudinea, Piscicolidae) from Dasyatis akajei (Chondrichthyes: Dasyatididae) in the northwestern Pacific.
J Parasitol.    impact factor:   1.485
2000;  86(4): 696-9

271:  Wise MR, Janovy J Jr, Wise JC.
Host specificity in Metamera sillasenorum, n. sp., a gregarine parasite of the leech Helobdella triserialis with notes on transmission dynamics.
J Parasitol.    impact factor:   1.485
2000;  86(3): 602-6

272:  Light JE, Siddall ME.
Phylogeny of the leech family Glossiphoniidae based on mitochondrial gene sequences and morphological data.
J Parasitol.    impact factor:   1.485
1999;  85(5): 815-23

273:  Tuncali D, Terzioglu A, Aslan G.
Leech resistance: how to deal with it.
Plast Reconstr Surg.    impact factor:   1.482
2003;  111(1): 508-9

274:  Conforti ML, Connor NP, Heisey DM, Hartig GK.
Evaluation of performance characteristics of the medicinal leech (Hirudo medicinalis) for the treatment of venous congestion.
Plast Reconstr Surg.    impact factor:   1.482
2002;  109(1): 228-35

275:  Gampper TJ, Celin JF.
The leech pond: a translation and commentary on the notes of Professor Luigi Zersi.
Plast Reconstr Surg.    impact factor:   1.482
2001;  107(2): 519-22

276:  MacGill KA.
The "chemical leech" revisited.
Plast Reconstr Surg.    impact factor:   1.482
2000;  105(6): 2272-3

277:  Lozano DD, Stephenson LL, Zamboni WA.
Effect of hyperbaric oxygen and medicinal leeching on survival of axial skin flaps subjected to total venous occlusion.
Plast Reconstr Surg.    impact factor:   1.482
1999;  104(4): 1029-32

278:  Robinson C.
Artificial leech technique.
Plast Reconstr Surg.    impact factor:   1.482
1998;  102(5): 1787-8

279:  Walton RL, Beahm EK, Brown RE, Upton J, Reinke K, Fudem G, Banis J, Davidson J, Dabb R, Kalimuthu R, Kitzmiller WJ, Gottlieb LJ, Buncke HJ.
Microsurgical replantation of the lip: a multi-institutional experience.
Plast Reconstr Surg.    impact factor:   1.482
1998;  102(2): 358-68

280:  Weinfeld AB, Kattash M, Grifka R, Friedman JD.
Leech therapy in the management of acute venous congestion of an infant's lower limb.
Plast Reconstr Surg.    impact factor:   1.482
1998;  102(5): 1611-4

281:  Shah S.
What the leechmaster taught me.
Acad Med.    impact factor:   1.472
1999;  74(1): 2

282:  Utevskaia OM, Atramentova LA.
[Predicting efficiency of selection on reproductive traits in the medicinal leech Hirudo medicinalis L.]
Genetika.    impact factor:   1.44
2002;  38(3): 316-22

283:  Utevskaia OM, Atramentova LA.
[Inheritance of reproductive traits of medicinal leeches (Hirudo medicinalis L.).]
Genetika.    impact factor:   1.44
2002;  38(1): 56-62

284:  Scrimgeour GJ, Wicklum D, Pruss SD.
Selection of an aquatic indicator species to monitor organic contaminants in trophically simple lotic food webs
Arch Environ Contam Toxicol.    impact factor:   1.437
1998;  35(4): 565-72

285:  Deitmer JW, Lohr C, Britz FC, Schmidt J.
Glial signalling in response to neuronal activity in the leech central nervous system.
Prog Brain Res.    impact factor:   1.425
2001;  132: 215-26

286:  Laurent V, Stefano GB, Salzet M.
The leech angiotensin-converting enzyme.
Ann N Y Acad Sci.    impact factor:   1.381
1998;  839: 500-2

287:  O'Gara BA, Abbasi A, Kaniecki K, Sarder F, Liu J, Narine LH.
Pharmacological characterization of the response of the leech pharynx to acetylcholine.
J Exp Zool.    impact factor:   1.353
1999;  284(7): 729-41

288:  Fujino Y, Nagahama T, Oumi T, Ukena K, Morishita F, Furukawa Y, Matsushima O, Ando M, Takahama H, Satake H, Minakata H, Nomoto K.
Possible functions of oxytocin/vasopressin-superfamily peptides in annelids with special reference to reproduction and osmoregulation.
J Exp Zool.    impact factor:   1.353
1999;  284(4): 401-6

289:  Schnizler M, Clauss W.
Characterization of a voltage-dependent conductance in the basolateral membrane of leech skin epithelium.
J Comp Physiol [B].    impact factor:   1.324
1998;  168(4): 295-302

290:  Kornreich L, Kleinhaus AL.
Postingestive chemosensation and feeding by leeches.
Physiol Behav.    impact factor:   1.285
1999;  67(5): 635-41

291:  Utley DS, Koch RJ, Goode RL.
The failing flap in facial plastic and reconstructive surgery: role of the medicinal leech.
Laryngoscope.    impact factor:   1.266
1998;  108(8 Pt 1): 1129-35

292:  Nikonov GI, Titova EA.
Destabilase complexes--natural liposome produced by medicinal leeches Hirudo medicinalis.
Fundam Clin Pharmacol.    impact factor:   1.265
1999;  13(1): 102-6

293:  West DJ, Andrews EB, McVean AR, Thorndyke MC, Taylor JD.
Present of a toxin in the salivary glands of the marine snail Cymatium intermedius that targets nicotinic acetylcholine receptors.
Toxicon.    impact factor:   1.248
1998;  36(1): 25-9

294:  Pinato G, Battiston S, Torre V.
Statistical independence and neural computation in the leech ganglion.
Biol Cybern.    impact factor:   1.199
2000;  83(2): 119-30

295:  Friedman J, Fabre J, Netscher D, Jaksic T.
Treatment of acute neonatal vascular injuries--the utility of multiple interventions.
J Pediatr Surg.    impact factor:   1.185
1999;  34(6): 940-5

296:  Royuel M, Hugon G, Rivier F, Paniagua R, Mornet D.
Dystrophin-associated proteins in obliquely striated muscle of the leech Pontobdella muricata (Annelida, Hirudinea).
Histochem J.    impact factor:   1.161
2001;  33(3): 135-9

297:  Royuela M, Paniagua R, Rivier F, Hugon G, Robert A, Mornet D.
Presence of invertebrate dystrophin-like products in obliquely striated muscle of the leech, Pontobdella muricata (Annelida, Hirudinea).
Histochem J.    impact factor:   1.161
1999;  31(9): 603-8

298:  Bird GA, Hesslein RH, Mills KH, Schwartz WJ, Turner MA.
Bioaccumulation of radionuclides in fertilized Canadian Shield lake basins.
Sci Total Environ.    impact factor:   1.126
1998;  218(1): 67-83

299:  O'Gara BA, Illuzzi FA, Chung M, Portnoy AD, Fraga K, Frieman VB.
Serotonin induces four pharmacologically separable contractile responses in the pharynx of the leech Hirudo medicinalis.
Gen Pharmacol.    impact factor:   1.105
1999;  32(6): 669-81

300:  Upshaw J, O'Leary JP.
The medicinal leech: past and present.
Am Surg.    impact factor:   1.101
2000;  66(3): 313-4

301:  Zavalova LL, Basanova AV, Baskova IP.
Fibrinogen-fibrin system regulators from bloodsuckers.
Biochemistry (Mosc).    impact factor:   1.05
2002;  67(1): 135-42

302:  Basanova AV, Baskova IP, Zavalova LL.
Vascular-platelet and plasma hemostasis regulators from bloodsucking animals.
Biochemistry (Mosc).    impact factor:   1.05
2002;  67(1): 143-50

303:  Baskova IP, Zavalova LL, Basanova AV, Sass AV.
Separation of monomerizing and lysozyme activities of destabilase from medicinal leech salivary gland secretion.
Biochemistry (Mosc).    impact factor:   1.05
2001;  66(12): 1368-73

304:  Baskova IP, Zavalova LL.
Proteinase inhibitors from the medicinal leech Hirudo medicinalis.
Biochemistry (Mosc).    impact factor:   1.05
2001;  66(7): 703-14

305:  Minakata H, Ikeda T, Nagahama T, Oumi T, Ukena K, Matsushima O, Kawano T, Kimura Y.
Comparison of precursor structures of the GGNG peptides derived from the earthworm Eisenia foetida and the leech Hirudo nipponia.
Biosci Biotechnol Biochem.    impact factor:   1.039
1999;  63(2): 443-5

306:  de Eguileor M, Grimaldi A, Tettamanti G, Congiu T, Protasoni M, Reguzzoni M, Valvassori R, Lanzavecchia G.
Ultrastructure and functional versatility of hirudinean botryoidal tissue.
Tissue Cell.    impact factor:   1.028
2001;  33(4): 332-41

307:  de Eguileor M, Grimaldi A, Tettamanti G, Valvassori R, Cooper EL, Lanzavecchia G.
Different types of response to foreign antigens by leech leukocytes.
Tissue Cell.    impact factor:   1.028
2000;  32(1): 40-8

308:  de Eguileor M, Grimaldi A, Tettamanti G, Valvassori R, Cooper EL, Lanzavecchia G.
Lipopolysaccharide-dependent induction of leech leukocytes that cross-react with vertebrate cellular differentiation markers.
Tissue Cell.    impact factor:   1.028
2000;  32(5): 437-45

309:  Riehl B, Schlue WR.
Morphological organization of neuropile glial cells in the central nervous system of the medicinal leech (Hirudo medicinalis).
Tissue Cell.    impact factor:   1.028
1998;  30(2): 177-86

310:  Pastor Gomez J, Lopez De Armentia M, Mendioroz M.
[The effects of axotomy on the nociceptive neurons of the leech]
Rev Neurol.    impact factor:   1.013
2002;  35(11): 1001-9

311:  Krauthamer V, Crosheck T.
Effects of high-rate electrical stimulation upon firing in modelled and real neurons.
Med Biol Eng Comput.    impact factor:   1.004
2002;  40(3): 360-6

312:  Shishikura F, Ochiai T, Yamanaka I.
Leech extracellular hemoglobin: two globin strains that are akin to vertebrate hemoglobin alpha and beta chains.
Zoolog Sci.    impact factor:   .969
1997;  14(6): 923-30

313:  de Eguileor M, Tettamanti G, Grimaldi A, Boselli A, Scari G, Valvassori R, Cooper EL, Lanzavecchia G.
Histopathological changes after induced injury in leeches.
J Invertebr Pathol.    impact factor:   .96
1999;  74(1): 14-28

314:  Huguet G, Verdaguer C, Molinas M.
Wound healing after silver nitrate burns in the leech hirudo medicinalis
J Invertebr Pathol.    impact factor:   .96
1999;  73(1): 15-24

315:  Shankland M, Bruce AE.
Axial patterning in the leech: developmental mechanisms and evolutionary implications.
Biol Bull.    impact factor:   .925
1998;  195(3): 370-2

316:  Baskova I, Zavalova L, Berezhnoy S, Avdonin P, Afanasjeva G, Popov E, Gabbasov Z.
Inhibition of induced and spontaneous platelet aggregation by destabilase from medicinal leech.
Platelets.    impact factor:   .882
2000;  11(2): 83-6

317:  Michalsen A, Moebus S, Spahn G, Esch T, Langhorst J, Dobos GJ.
Leech therapy for symptomatic treatment of knee osteoarthritis: results and implications of a pilot study.
Altern Ther Health Med.    impact factor:   .879
2002;  8(5): 84-8

318:  Dossey L.
Maggots and leeches: when science and aesthetics collide.
Altern Ther Health Med.    impact factor:   .879
2002;  8(4): 12-6, 106-7

319:  Siragusa M, Schepis C, Palazzo R, Fabrizi G, Guarneri B, Del Gracco S, Spada RS, Ferri R.
Skin pathology findings in a cohort of 1500 adult and elderly subjects.
Int J Dermatol.    impact factor:   .867
1999;  38(5): 361-6

320:  Akyurek M, Safak T, Kecik A.
Microsurgical ear replantation without venous repair: failure of development of venous channels despite patency of arterial anastomosis for 14 days.
Ann Plast Surg.    impact factor:   .864
2001;  46(4): 439-42; discussion 442-3

321:  Eroglu C, Hokelek M, Guneren E, Esen S, Pekbay A, Uysal OA.
Bacterial Flora of Hirudo medicinalis and Their Antibiotic Sensitivities in the Middle Black Sea Region, Turkey.
Ann Plast Surg.    impact factor:   .864
2001;  47(1): 70-3

322:  Cottler PS, Skalak TC.
Development of a clinically useful mechanical leech device that promotes flap survival in an animal model of venous-congested skin flaps.
Ann Plast Surg.    impact factor:   .864
2001;  47(2): 138-47

323:  Guneren E, Hokelek M, Eroglu C, Uysal OA.
Re: Aeromonas species isolated from medicinal leeches.
Ann Plast Surg.    impact factor:   .864
2000;  45(5): 568-9

324:  Guneren E, Erolu L, Akba H, Uysal OA, Hokelek M, Erolu C.
The use of Hirudo medicinalis in nipple-areolar congestion.
Ann Plast Surg.    impact factor:   .864
2000;  45(6): 679-81

325:  Weinfeld AB, Yuksel E, Boutros S, Gura DH, Akyurek M, Friedman JD.
Clinical and scientific considerations in leech therapy for the management of acute venous congestion: an updated review.
Ann Plast Surg.    impact factor:   .864
2000;  45(2): 207-12

326:  Chun JK, Sterry TP, Margoles SL, Silver L.
Salvage of ear replantation using the temporoparietal fascia flap.
Ann Plast Surg.    impact factor:   .864
2000;  44(4): 435-9

327:  Mackay DR, Manders EK, Saggers GC, Banducci DR, Prinsloo J, Klugman K.
Aeromonas species isolated from medicinal leeches.
Ann Plast Surg.    impact factor:   .864
1999;  42(3): 275-9

328:  Cho BH, Ahn HB.
Microsurgical replantation of a partial ear, with leech therapy.
Ann Plast Surg.    impact factor:   .864
1999;  43(4): 427-9

329:  MacQuillan A, Jones ME, Gault D.
Taking a leech to blood: but can you make him drink?
Br J Plast Surg.    impact factor:   .826
2002;  55(6): 540-1

330:  Haeseker B.
Johann Friedrich Dieffenbach: successful use of leeches in plastic surgery in the 1820s.
Br J Plast Surg.    impact factor:   .826
2001;  54(3): 279

331:  Sawyer RT.
Johann Friedrich Dieffenbach: successful use of leeches in plastic surgery in the 1820s.
Br J Plast Surg.    impact factor:   .826
2000;  53(3): 245-7

332:  Hage JJ, Karim RB.
Johann Friedrich Dieffenbach: successful use of leeches in plastic surgery in the 1820s.
Br J Plast Surg.    impact factor:   .826
2000;  53(7): 632-3

333:  Pereira JA, Greig JR, Liddy H, Ion L, Moss AL.
Leech-borne Serratia marcescens infection following complex hand injury.
Br J Plast Surg.    impact factor:   .826
1998;  51(8): 640-1

334:  Mortenson BW, Dawson KH, Murakami C.
Medicinal leeches used to salvage a traumatic nasal flap.
Br J Oral Maxillofac Surg.    impact factor:   .771
1998;  36(6): 462-4

335:  Salgueiro S, Potts S, McIlgorm EA, Ansell KH, Hemberger J, Gussow D.
A protein from the salivary glands of the giant Amazon leech with high sequence homology to a nicotinic acetylcholine receptor subunit.
Z Naturforsch [C].    impact factor:   .709
1999;  54(11): 963-71

336:  Dorling A, Chen D, Riesbeck K, McVey J, Kemball-Cook G, Tuddenham EG, Lechler RI.
Regulated endothelial cell expression of novel anticoagulants: a strategy for the prevention and therapy of intravascular thrombosis.
Transplant Proc.    impact factor:   .678
2000;  32(5): 971

337:  Csoka TB, Frost GI, Stern R.
Hyaluronidases in tissue invasion.
Invasion Metastasis.    impact factor:   .677
1997;  17(6): 297-311

338:  Kaygusuz I, Yalcin S, Keles E.
Leeches in the larynx.
Eur Arch Otorhinolaryngol.    impact factor:   .646
2001;  258(9): 455-7

339:  Pacuszka T, Panasiewicz M.
Photochemical labeling of human erythrocyte membrane proteins with radioiodinated 4-azidosalicylic acid derivatives of G(M3), G(D3), G(M1), and FucG(M1) gangliosides.
Acta Biochim Pol.    impact factor:   .569
1998;  45(2): 509-21

340:  Font WF.
Parasites in paradise: patterns of helminth distribution in hawaiian stream fishes
J Helminthol.    impact factor:   .564
1998;  72(4): 307-11

341:  Cemerikic D, Nedeljkov V, Lopicic S, Dragovic S, Beleslin B.
Excitotoxicity of lathyrus sativus neurotoxin in leech retzius neurons.
Physiol Res.    impact factor:   .521
2001;  50(2): 205-14

342:  De-Miguel FF.
Steps in the formation of neurites and synapses studied in cultured leech neurons.
Braz J Med Biol Res.    impact factor:   .517
2000;  33(5): 487-97

343:  Sawyer RT.
The trade in medicinal leeches in the southern Indian Ocean in the nineteenth century.
Med Hist.    impact factor:   .513
1999;  43(2): 241-5

344:  Talbi M, Stussi JD, Meley M.
Microsurgical replantation of a totally amputated ear without venous repair.
J Reconstr Microsurg.    impact factor:   .494
2001;  17(6): 417-20

345:  La Scala GC, Carroll SM, Forrest CR, Zuker RM.
Use of a mechanical leech in a reverse-flow radial forearm flap: case report.
J Reconstr Microsurg.    impact factor:   .494
2001;  17(5): 335-40

346:  Irish JC, Gullane PJ, Mulholland S, Neligan PC.
Medicinal leech in head and neck reconstruction.
J Otolaryngol.    impact factor:   .482
2000;  29(5): 327-32

347:  Deka PM, Rajeev TP.
Unusual cause of hematuria.
Urol Int.    impact factor:   .478
2001;  66(1): 41-2

348:  Samama MM.
[Once upon a time there was hirudin...]
Presse Med.    impact factor:   .429
1998;  27 Suppl 2: 5-6

349:  al-Hadrani A, Debry C, Faucon F, Fingerhut A.
Hoarseness due to leech ingestion.
J Laryngol Otol.    impact factor:   .418
2000;  114(2): 145-6

350:  Baskova IP, Zavalova LL, Basanova AV, Grigor'eva OV.
[The hydrolysis of Glu(gamma-epsilon)Lys-amide bonds in D-dimer fragment of fibrin by destabilase from medicinal leech]
Bioorg Khim.    impact factor:   .397
1999;  25(6): 435-8

351:  Mosolov VV.
[New studies on natural inhibitors of proteolytic enzymes]
Bioorg Khim.    impact factor:   .397
1998;  24(5): 332-40

352:  Bapat RD, Acharya BS, Juvekar S, Dahanukar SA.
Leech therapy for complicated varicose veins.
Indian J Med Res.    impact factor:   .365
1998;  107: 281-4

353:  Iraqi MR, Squali FZ.
[Hematemesis and respiratory airway obstruction due to leeches]
Arch Pediatr.    impact factor:   .303
1999;  6(4): 479-80

354:  Maksimov GV, Chatterdzhi Sh, Kleinhaus AL, Rubin AB.
[Role of Ca2+ in regulating the serotonin-dependent synapse between P and R-cells of leech segmented ganglion]
Biofizika.    impact factor:   .303
1999;  44(4): 694-9

355:  Greig AV.
J R Soc Med.    impact factor:   .27
2002;  95(1): 55

356:  Aronson ME.
J R Soc Med.    impact factor:   .27
2001;  94(7): 372

357:  Sinclair-Loutit KW.
J R Soc Med.    impact factor:   .27
2001;  94(5): 2259

358:  Eccles SJ, Butler PE.
J R Soc Med.    impact factor:   .27
2001;  94(4): 206

359:  Carter KC.
Leechcraft in nineteenth century British medicine.
J R Soc Med.    impact factor:   .27
2001;  94(1): 38-42

360:  Edelman JR, Lin YJ.
Heterochromatin (chromocentres) and regeneration of invertebrates and vertebrates: a correlation.
Cytobios.    impact factor:   .239
1997;  92(368): 7-21

361:  Pryor SC, Elizee R.
Evidence of opiates and opioid neuropeptides and their immune effects in parasitic invertebrates representing three different phyla: Schistosoma mansoni, Theromyzon tessulatum, Trichinella spiralis.
Acta Biol Hung.    impact factor:   .219
2000;  51(2-4): 331-41

362:  Sharma S, Goyal A, Jha AK, Upadhya S, Mishra SC.
Leech infestation: an unusual cause of hoarseness.
Trop Doct.    impact factor:   .198
2002;  32(1): 40

363:  Litch JA, Bishop RA.
Saturated aqueous sodium chloride solution for the removal of leeches.
Trop Doct.    impact factor:   .198
2000;  30(2): 102

364:  Lotz RG, Fuchs H, Bertsche U.
Long-term biological investigations in space.
Acta Astronaut.    impact factor:   .156
1975;  2(1-2): 41-8

365:  Rosner F.
The medicinal leech in Jewish writings.
Isr Med Assoc J.    impact factor:   .027
1999;  1(4): 296-8

366:  Shenfeld OZ.
Successful use of the medicinal leech (Hirudo medicinalis) for the treatment of venous insufficiency in a replanted digit.
Isr Med Assoc J.    impact factor:   .027
1999;  1(3): 221

367:  Gur E, Eldor A.
Medicinal leeches for the salvage of a replanted digit.
Isr Med Assoc J.    impact factor:   .027
1999;  1(1): 62

368:  Ahmadizadeh A.
Leech infestation as a potential cause of hemoptysis in childhood.
Arch Otolaryngol Head Neck Surg.    impact factor:   0
2002;  128(1): 92

369:  Mohammad Y, Rostum M, Dubaybo BA.
Laryngeal hirudiniasis: an unusual cause of airway obstruction and hemoptysis.
Pediatr Pulmonol.    impact factor:   0
2002;  33(3): 224-6

370:  Garcia AC, Martin AM, De Luna Gijon CA, Martin Anaya AS, Mondejar AR.
Leech in the epiglottis: an unusual discovery in our times.
Am J Otolaryngol.    impact factor:   0
2002;  23(2): 91-2

371:  Jin W, Zhang RJ.
Pressure sensation by an anterior pagoda neuron population distributed in multiple ganglia in the leech, Whitmania pigra.
J Comp Physiol A Neuroethol Sens Neural Behav Physiol.    impact factor:   0
2002;  188(3): 165-71

372:  Ventura AC, Mindlin GB, Dawson SP.
Generic two-variable model of excitability.
Phys Rev E Stat Nonlin Soft Matter Phys.    impact factor:   0
2002;  65(4 Pt 2A): 046231

373:  Bilgen C, Karci B, Uluoz U.
A nasopharyngeal mass: leech in the nasopharynx.
Int J Pediatr Otorhinolaryngol.    impact factor:   0
2002;  64(1): 73-6

374:  Kubo T, Yano K, Hosokawa K.
Management of flaps with compromised venous outflow in head and neck microsurgical reconstruction.
Microsurgery.    impact factor:   0
2002;  22(8): 391-5

375:  Gladyshev MI, Moskvicheva AV.
Baikal invaders have become dominant in the upper Yenisei benthofauna.
Dokl Biol Sci.    impact factor:   0
2002;  383(1-6): 138-40

376:  Lapkina LN, Zharikova TI, Svirskii AM.
[Invasion of fish with leeches (Fam. Piscicolidae) in reservoirs of the Volga river]
Parazitologiia.    impact factor:   0
2002;  36(2): 132-9

377:  Salzet M, Verger-Bocquet M.
Cellular localization of a chromogranin B-like derived peptides in leeches.
Neuroendocrinol Lett.    impact factor:   0
2002;  23(3): 209-12

378:  Chepeha DB, Nussenbaum B, Bradford CR, Teknos TN.
Leech therapy for patients with surgically unsalvageable venous obstruction after revascularized free tissue transfer.
Arch Otolaryngol Head Neck Surg.    impact factor:   0
2002;  128(8): 960-5

379:  Tan E, Pan Z, Huang L.
[Relationship between population dynamic of freshwater leech Whitmania laevis and chemical factors of water]
Ying Yong Sheng Tai Xue Bao.    impact factor:   0
2002;  13(5): 593-5

380:  Fernandez J, Cantillana V, Ubilla A.
Reorganization and translocation of the ectoplasmic cytoskeleton in the leech zygote by condensation of cytasters and interactions of dynamic microtubules and actin filaments.
Cell Motil Cytoskeleton.    impact factor:   0
2002;  53(3): 214-30

381:  White HD, Chew DP.
Bivalirudin: an anticoagulant for acute coronary syndromes and coronary interventions.
Expert Opin Pharmacother.    impact factor:   0
2002;  3(6): 777-88

382:  Zhokhov AE, Pugacheva MN.
[Parasites-invaders of the Volga river basin: history of invasion, perspective of dispersion, possibility of epizootic]
Parazitologiia.    impact factor:   0
2001;  35(3): 201-12

383:  Zoccolan D, Giachetti A, Torre V.
The use of optical flow to characterize muscle contraction.
J Neurosci Methods.    impact factor:   0
2001;  110(1-2): 65-80

384:  Andrews S.
Hirudo medicinalis: the medicinal leech.
J Audiov Media Med.    impact factor:   0
2001;  24(3): 126-7

385:  Salzet M, Verger-Bocquet M.
Elements of angiotensin system are involved in leeches and mollusks immune response modulation.
Brain Res Mol Brain Res.    impact factor:   0
2001;  94(1-2): 137-47

386:  Roth JH.
[The leech--use in animals]
Schweiz Arch Tierheilkd.    impact factor:   0
2001;  143(10): 516-7

387:  Kilb W, Schlue WR.
Feedback control of intracellular pH by means of iontophoretic H+/OH- injection.
Pflugers Arch.    impact factor:   0
2001;  443(1): 54-60

388:  Cang J, Yu X, Friesen WO.
Sensory modification of leech swimming: interactions between ventral stretch receptors and swim-related neurons.
J Comp Physiol [A].    impact factor:   0
2001;  187(7): 569-79

389:  Tan E, Liang C.
[Toxicity of different pesticides to Haemadipsa hainana and its control]
Ying Yong Sheng Tai Xue Bao.    impact factor:   0
2001;  12(2): 266-8

390:  Sohn JH, Kang HA, Rao KJ, Kim CH, Choi ES, Chung BH, Rhee SK.
Current status of the anticoagulant hirudin: its biotechnological production and clinical practice.
Appl Microbiol Biotechnol.    impact factor:   0
2001;  57(5-6): 606-13

391:  Salzet M, Verger-Bocquet M.
Cellular localization of a renin-like enzyme in leeches.
Neuroendocrinol Lett.    impact factor:   0
2001;  22(6): 453-9

392:  Chalisova NI, Pennijajnen VP, Baskova IP, Zavalova LL, Bazanova AV.
[Neurite-stimulating activity of secretions from the Hirudo medicinalis salivary gland in cultured sensory neurons]
Ross Fiziol Zh Im I M Sechenova.    impact factor:   0
2001;  87(12): 1650-5

393:  Stamenova PK, Marchetti T, Simeonov I.
Efficacy and safety of topical hirudin (Hirudex): a double-blind, placebo-controlled study.
Eur Rev Med Pharmacol Sci.    impact factor:   0
2001;  5(2): 37-42

394:  Nawarskas JJ, Anderson JR.
Bivalirudin: a new approach to anticoagulation.
Heart Dis.    impact factor:   0
2001;  3(2): 131-7

395:  Zuba K.
[The treatment of "Rybenka": therapies and medical operations on Michal Kazimierz Radziwill, 1702-1762]
Med Nowozytna.    impact factor:   0
2001;  8(1): 89-110

396:  de Eguileor M, Grimaldi A, Tettamanti G, Ferrarese R, Congiu T, Protasoni M, Perletti G, Valvassori R, Lanzavecchia G.
Hirudo medicinalis: a new model for testing activators and inhibitors of angiogenesis.
Angiogenesis.    impact factor:   0
2001;  4(4): 299-312

397:  Matias I, Bisogno T, Melck D, Vandenbulcke F, Verger-Bocquet M, De Petrocellis L, Sergheraert C, Breton C, Di Marzo V, Salzet M.
Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis.
Brain Res Mol Brain Res.    impact factor:   0
2001;  87(2): 145-59

398:  Martin P.
On the origin of the Hirudinea and the demise of the Oligochaeta.
Proc R Soc Lond B Biol Sci.    impact factor:   0
2001;  268(1471): 1089-98

399:  Beck A, Lohr C, Nett W, Deitmer JW.
Bursting activity in leech Retzius neurons induced by low external chloride.
Pflugers Arch.    impact factor:   0
2001;  442(2): 263-72

400:  Rester U, Bode W, Sampaio CA, Auerswald EA, Lopes AP.
Cloning, purification, crystallization and preliminary X-ray diffraction analysis of the antistasin-type inhibitor ghilanten (domain I) from Haementeria ghilianii in complex with porcine beta-trypsin.
Acta Crystallogr D Biol Crystallogr.    impact factor:   0
2001;  57(Pt 7): 1038-41

401:  Kourakis MJ, Martindale MQ.
Hox gene duplication and deployment in the annelid leech Helobdella.
Evol Dev.    impact factor:   0
2001;  3(3): 145-53

402:  Huizinga EG, Schouten A, Connolly TM, Kroon J, Sixma JJ, Gros P.
The structure of leech anti-platelet protein, an inhibitor of haemostasis.
Acta Crystallogr D Biol Crystallogr.    impact factor:   0
2001;  57(Pt 8): 1071-8

403:  Kim YH, Choi JG, Lee GM, Kang KW.
Domain and genomic sequence analysis of bdellin-KL, a leech-derived trypsin-plasmin inhibitor.
J Biochem (Tokyo).    impact factor:   0
2001;  130(3): 431-8

404:  Chalisova NI, Baskova IP, Zavalova LL, Pennijainen VA.
[Neurite-stimulating effect of Hirudo medicinalis salivary gland secreting factors in organotypic culture of the dorsal root ganglia]
Ross Fiziol Zh Im I M Sechenova.    impact factor:   0
2001;  87(6): 815-20

405:  Salzet M, Deloffre L.
PLGamide characterization and role in osmoregulation in leech brain.
Brain Res Mol Brain Res.    impact factor:   0
2000;  76(1): 161-9

406:  Rester U, Moser M, Huber R, Bode W.
L-Isoaspartate 115 of porcine beta-trypsin promotes crystallization of its complex with bdellastasin.
Acta Crystallogr D Biol Crystallogr.    impact factor:   0
2000;  56 ( Pt 5): 581-8

407:  Giusti AF, Hinman VF, Degnan SM, Degnan BM, Morse DE.
Expression of a Scr/Hox5 gene in the larval central nervous system of the gastropod Haliotis, a non-segmented spiralian lophotrochozoan.
Evol Dev.    impact factor:   0
2000;  2(5): 294-302

408:  Ukhanov K, Walz B.
The phosphoinositide signaling cascade is involved in photoreception in the leech Hirudo medicinalis.
J Comp Physiol [A].    impact factor:   0
2000;  186(12): 1171-83

409:  Sieks B, Hochstrate P, Schlue WR.
Activation and desensitization of the caffeine-sensitive cation channels and calcium stores have no persistent effect on the electrophysiological properties of leech P neurones.
Comp Biochem Physiol C Toxicol Pharmacol.    impact factor:   0
2000;  127(3): 273-9

410:  Minelli A.
Holomeric vs. meromeric segmentation: a tale of centipedes, leeches, and rhombomeres.
Evol Dev.    impact factor:   0
2000;  2(1): 35-48

411:  Soto JM.
Marine leech, Stibarobdella macrothela (Schmarda, 1861) (Hirudinea, piscicolidae), parasitic on the whaler shark, Carcharhinus Brachyurus (Gunther, 1870) (Chondrichthyes, Carcharhinidae), in Southern Brazilian waters.
Braz J Biol.    impact factor:   0
2000;  60(4): 713-4

412:  Shinkman R.
Worms and squirms. Maggots, leeches are making a comeback in modern medicine.
Mod Healthc.    impact factor:   0
2000;  30(43): 54-5

413:  Marin-Burgin A, Szczupak L.
Processing of sensory signals by a non-spiking neuron in the leech.
J Comp Physiol [A].    impact factor:   0
2000;  186(10): 989-97

414:  Hocker CG, Yu X, Friesen WO.
Functionally heterogeneous segmental oscillators generate swimming in the medical leech.
J Comp Physiol [A].    impact factor:   0
2000;  186(9): 871-83

415:  Brunelli M, Garcia-Gil M, Mozzachiodi R, Roberto M, Scuri R, Traina G, Zaccardi ML.
Neurotoxic effects of caulerpenyne.
Prog Neuropsychopharmacol Biol Psychiatry.    impact factor:   0
2000;  24(6): 939-54

416:  Eisenhart FJ, Cacciatore TW, Kristan WB Jr.
A central pattern generator underlies crawling in the medicinal leech.
J Comp Physiol [A].    impact factor:   0
2000;  186(7-8): 631-43

417:  Cheikh-Rouhou F, Besbes M, Makni F, Chaabouni M, Ayadi A.
[Limnatis nilotica, cause of severe anemia in an infant]
Med Trop (Mars).    impact factor:   0
2000;  60(1): 100-1

418:  Punin MIu, Kazakov VK, Mkrtchian LG.
[Immunohistochemical detection of the regulator cells in the leech digestive system]
Zh Evol Biokhim Fiziol.    impact factor:   0
2000;  36(2): 141-6

419:  Wright SM, Finical J.
Beyond leeches. Therapeutic phlebotomy today.
Am J Nurs.    impact factor:   0
2000;  100(7): 55-9, 61, 63

420:  Dorovskikh GN.
[The results of a study of the species composition of fish parasites in the river basins of northeastern European Russia. Leeches (Hirudinea), mollusks (Mollusca), crayfish (Crustacea) and arachnids (Arachnida)]
Parazitologiia.    impact factor:   0
2000;  34(2): 158-63

421:  Tasiemski A, Verger-Bocquet M, Cadet M, Goumon Y, Metz-Boutigue MH, Aunis D, Stefano GB, Salzet M.
Proenkephalin A-derived peptides in invertebrate innate immune processes.
Brain Res Mol Brain Res.    impact factor:   0
2000;  76(2): 237-52

422:  Liu L, Jin R, Xu G.
[HPLC determination of uracil xanthine, hypoxanthine and uridine in species of animal drugs]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1999;  24(2): 73-6, 124

423:  Tan Y, Xu P, Zhang X, Zhao S.
[Research on anti-thrombosis effect of ethanol extract from beheaded leech (EEBL)]
Zhongguo Zhong Yao Za Zhi.    impact factor:   0
1999;  24(10): 622-3, 640

424:  Cheng-Lai A.
Cardiovascular drug highlight: hirudin.
Heart Dis.    impact factor:   0
1999;  1(1): 41-9

425:  de la Fuente Aguado J, Nodar Germinas A, Touza Rey F, Crespo Casal M, Arnillas Gomez E, Martinez Vazquez C.
[Cellulitis caused by Aeromonas hydrophila]
An Med Interna.    impact factor:   0
1999;  16(12): 635-6

426:  Nikonov GI, Titova EA, Seleznev KG.
[Biological activity of pharmacological properties of the anticoagulant complex (hirudin, plasma kallikrein inhibitor, prostaglandin) from the leech Hirudo medicinalis]
Biull Eksp Biol Med.    impact factor:   0
1999;  128(12): 673-6

427:  Hovingh P, Linker A.
Hyaluronidase activity in leeches (Hirudinea).
Comp Biochem Physiol B Biochem Mol Biol.    impact factor:   0
1999;  124(3): 319-26

428:  Lewis JE.
Sensory processing and the network mechanisms for reading neuronal population codes.
J Comp Physiol [A].    impact factor:   0
1999;  185(4): 373-8

429:  De Eguileor M, Grimaldi A, Boselli A, Tettamanti G, Lurati S, Valvassori R, Lanzavecchia G.
Possible roles of extracellular matrix and cytoskeleton in leech body wall muscles.
J Microsc.    impact factor:   0
1999;  196(1): 6-18

430:  Nikonov GI, Titova EA, Seleznev KG.
A stable prostacyclin-like substance produced by the medicinal leech Hirudo medicinalis.
Prostaglandins Other Lipid Mediat.    impact factor:   0
1999;  58(1): 1-7

431:  Cottler PS, Gampper TJ, Rodeheaver GT, Skalak TC.
Evaluation of clinically applicable exsanguination treatments to alleviate venous congestion in an animal skin flap model.
Wound Repair Regen.    impact factor:   0
1999;  7(3): 187-95

432:  Chalisova NI, Zhuravskii SG, Penniiainen VA, Berezhnoi SN, Artamonova II, Zavalova LL, Baskova IP.
[The stimulating effect of destabilase, a component of Hirudo medicinalis salivary gland secretion, on sensory neuron neurite growth in organotypic culture]
Tsitologiia.    impact factor:   0
1999;  41(1): 48-52

433:  Lu J, Gramoll S, Schmidt J, Calabrese RL.
Motor pattern switching in the heartbeat pattern generator of the medicinal leech: membrane properties and lack of synaptic interaction in switch interneurons.
J Comp Physiol [A].    impact factor:   0
1999;  184(3): 311-24

434:  Iscla I, Arini PD, Szczupak L.
Differential channeling of sensory stimuli onto a motor neuron in the leech.
J Comp Physiol [A].    impact factor:   0
1999;  184(2): 233-41

435:  Fenollar F, Fournier PE, Legre R.
Unusual case of Aeromonas sobria cellulitis associated with the use of leeches.
Eur J Clin Microbiol Infect Dis.    impact factor:   0
1999;  18(1): 72-3

436:  Angstadt JD.
Persistent inward currents in cultured Retzius cells of the medicinal leech.
J Comp Physiol [A].    impact factor:   0
1999;  184(1): 49-61

437:  Hintz K, Gunzel D, Schlue WR.
Na+-dependent regulation of the free Mg2+ concentration in neuropile glial cells and P neurones of the leech Hirudo medicinalis.
Pflugers Arch.    impact factor:   0
1999;  437(3): 354-62

438:  Schmidt J.
Activity pattern of an oscillatory network after synaptic block in the leech central nervous system.
J Comp Physiol [A].    impact factor:   0
1998;  182(4): 501-7

439:  Parpura V, Tong W, Yeung ES, Haydon PG.
Laser-induced native fluorescence (LINF) imaging of serotonin depletion in depolarized neurons.
J Neurosci Methods.    impact factor:   0
1998;  82(2): 151-8

440:  Angstadt JD, Choo JJ, Saran AM.
Effects of transition metal ions on spontaneous electrical activity and chemical synaptic transmission of neurons in the medicinal leech.
J Comp Physiol [A].    impact factor:   0
1998;  182(3): 389-401

441:  Hernandez M, Ramirez Gutierrez RE.
[Internal hirudiniasis: vaginal bleeding resulting from leech bite]
Ginecol Obstet Mex.    impact factor:   0
1998;  66: 284-6

442:  Luo Y, Chou M, Li S, Li Y, Luo M.
Crystallization and preliminary X-ray studies of sialidase L from the leech Macrobdella decora.
Acta Crystallogr D Biol Crystallogr.    impact factor:   0
1998;  54 ( Pt 1): 111-3

443:  Nath RK, Kraemer BA, Azizzadeh A.
Complete ear replantation without venous anastomosis.
Microsurgery.    impact factor:   0
1998;  18(4): 282-5

444:  Ena IaM, Sushko EA, Solov'ev AV.
[The history of leech therapy]
Lik Sprava.    impact factor:   0
1998;  (5): 26-30

445:  Zipser B, Bradford JJ, Hollingsworth RI.
Cholesterol and its derivatives, are the principal steroids isolated from the leech species Hirudo medicinalis.
Comp Biochem Physiol C Pharmacol Toxicol Endocrinol.    impact factor:   0
1998;  120(2): 269-82

446:  Nazar PS, Doroshenko BH.
[The leech therapy of infectious myocarditis]
Lik Sprava.    impact factor:   0
1998;  (6): 146-8

447:  Sergeeva SS.
[Tetrodotoxin effect on spontaneous and evoked impulse activity of leech Retzius neurons]
Ross Fiziol Zh Im I M Sechenova.    impact factor:   0
1998;  84(8): 735-40

448:  Shafer OT, Chen A, Kumar SM, Muller KJ, Sahley CL.
Injury-induced expression of endothelial nitric oxide synthase by glial and microglial cells in the leech central nervous system within minutes after injury.
Proc R Soc Lond B Biol Sci.    impact factor:   0
1998;  265(1411): 2171-5

449:  Zhou Y, Zhu S.
[Anticoagulant peptides and proteins from leeches]
Zhonghua Xue Ye Xue Za Zhi.    impact factor:   0
1998;  19(9): 497-8

450:  Zhang T, Du L, Cui P.
[Experimental study of hirudo and Salvia miltiorrhiza on smooth muscle cell hyperplasia after balloon angioplasty]
Zhongguo Zhong Xi Yi Jie He Za Zhi.    impact factor:   0
1998;  18(3): 159-61

451:  Salzet B, Stefano GB, Verger-Bocquet M, Salzet M.
Putative leech dopamine1-like receptor molecular characterization: sequence homologies between dopamine and serotonin leech CNS receptors explain pharmacological cross-reactivities.
Brain Res Mol Brain Res.    impact factor:   0
1998;  58(1-2): 47-58

452:  Nett W, Deitmer JW.
Sodium-sensitive, calcium-independent potassium conductance in the leech giant glial cell
Pflugers Arch.    impact factor:   0
1998;  436(4): 608-14

453:  Baccus SA.
Synaptic facilitation by reflected action potentials: enhancement of transmission when nerve impulses reverse direction at axon branch points.
Proc Natl Acad Sci U S A.    impact factor:   0
1998;  95(14): 8345-50

454:  Salzet M, Salzet B, Sautiere P, Lesage J, Beauvillain JC, Bilfinger TV, Rialas C, Bjenning C, Stefano GB.
Isolation and characterization of a leech neuropeptide in rat brains: coupling to nitric oxide release in leech, rat and human tissues.
Brain Res Mol Brain Res.    impact factor:   0
1998;  55(1): 173-9

455:  Raper M.
Slimy little suckers.
Nurs Times.    impact factor:   0
1998;  94(13): 34-5

456:  Luo Y, Li SC, Chou MY, Li YT, Luo M.
The crystal structure of an intramolecular trans-sialidase with a NeuAc alpha2-->3Gal specificity.
Structure.    impact factor:   0
1998;  6(4): 521-30

457:  Thearle MJ.
Leeches in medicine.
Aust N Z J Surg.    impact factor:   0
1998;  68(4): 292-5

458:  Ji-Tuan X.
Four misdiagnosed cases of visceral bleeding caused by Haemadipha japonica.
Southeast Asian J Trop Med Public Health.    impact factor:   0
1997;  28(3): 673-4

459:  Hoylaerts MF.
Platelet-vessel wall interactions in thrombosis and restenosis role of von Willebrand factor.
Verh K Acad Geneeskd Belg.    impact factor:   0
1997;  59(3): 161-83

460:  Di Marco S, Priestle JP.
Structure of the complex of leech-derived tryptase inhibitor (LDTI) with trypsin and modeling of the LDTI-tryptase system.
Structure.    impact factor:   0
1997;  5(11): 1465-74

461:  Salzet M, Stefano G.
Prodynorphin in invertebrates.
Brain Res Mol Brain Res.    impact factor:   0
1997;  52(1): 46-52

462:  Wei AY, Li YQ, Chen JF.
[Clinical study on combined treatment of shuizhi tuyuan powder and nifedipine in treating hypertension patients complicated with left ventricular hypertrophy]
Zhongguo Zhong Xi Yi Jie He Za Zhi.    impact factor:   0
1996;  16(11): 652-4

463:  Maugendre P, Poinsotte V, Brassier N, Chast F.
[Not Available]
Rev Hist Pharm (Paris).    impact factor:   0
1996;  44(312 suppl): 385-8

464:  Zhu YZ, Kang B, Zhu QQ.
[Clinical study of shuizhi-dahuang mixture in treating schizophrenics with blood stasis syndrome]
Zhongguo Zhong Xi Yi Jie He Za Zhi.    impact factor:   0
1996;  16(11): 646-8

465:  Lotz RG, Baum P, Bowman GH, Klein KD, von Lohr R, Schrotter L.
Test of a life support system with Hirudo medicinalis in a sounding rocket.
Life Sci Space Res.    impact factor:   0
1972;  10: 133-43

466:  Lotz RG.
A life support system for satellite experiments over one year.
Life Sci Space Res.    impact factor:   0
1968;  6: 49-55


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