Ingredient ID 691 
Chinese Pronunciation MUBIEZIREN 
English Name Cochinchina Momordica Seed  
Latin Name Semen Momordicae  
Aliases LouCenZi
Identified Compounds

order by name

1. Alpha-eleostearic Acid

   C18H30O2   278.43

2. Gypsogenin

   C30H46O4   470.69

3. Momordic Acid

   C30H46O4   470.69

4. Mycose

   C12H22O11   342.29

Recipes that contain
  1. 8      ErFenWan
  2. 126      PangGuangTang

Available references (order by impact factor):

1:  Ogata F, Miyata T, Fujii N, Yoshida N, Noda K, Makisumi S, Ito A.
Purification and amino acid sequence of a bitter gourd inhibitor against an acidic amino acid-specific endopeptidase of Streptomyces griseus.
J Biol Chem.    impact factor:   7.666
1991;  266(25): 16715-21

2:  Numata T, Suzuki A, Yao M, Tanaka I, Kimura M.
Amino acid residues in ribonuclease MC1 from bitter gourd seeds which are essential for uridine specificity.
Biochemistry.    impact factor:   4.493
2001;  40(2): 524-30

3:  Hernandez JF, Gagnon J, Chiche L, Nguyen TM, Andrieu JP, Heitz A, Trinh Hong T, Pham TT, Le Nguyen D.
Squash trypsin inhibitors from Momordica cochinchinensis exhibit an atypical macrocyclic structure.
Biochemistry.    impact factor:   4.493
2000;  39(19): 5722-30

4:  Liu L, Hammond EG, Nikolau BJ.
In Vivo Studies of the Biosynthesis of [alpha]-Eleostearic Acid in the Seed of Momordica charantia L.
Plant Physiol.    impact factor:   4.434
1997;  113(4): 1343-1349

5:  Das MK, Khan MI, Surolia A.
Fluorimetric studies of the binding of Momordica charantia (bitter gourd) lectin with ligands.
Biochem J.    impact factor:   4.349
1981;  195(1): 341-3

6:  Barbieri L, Zamboni M, Lorenzoni E, Montanaro L, Sperti S, Stirpe F.
Inhibition of protein synthesis in vitro by proteins from the seeds of Momordica charantia (bitter pear melon).
Biochem J.    impact factor:   4.349
1980;  186(2): 443-52

7:  Barbieri L, Lorenzoni E, Stirpe F.
Inhibition of protein synthesis in vitro by a lectin from Momordica charantia and by other haemagglutinins.
Biochem J.    impact factor:   4.349
1979;  182(2): 633-5

8:  Ide H, Kimura M, Arai M, Funatsu G.
The complete amino acid sequence of ribonuclease from the seeds of bitter gourd (Momordica charantia).
FEBS Lett.    impact factor:   3.72
1991;  284(2): 161-4

9:  Wang H, Ng TB.
Ribosome inactivating protein and lectin from bitter melon (Momordica charantia) seeds: sequence comparison with related proteins.
Biochem Biophys Res Commun.    impact factor:   3.161
1998;  253(1): 143-6

10:  Pu Z, Lu BY, Liu WY, Jin SW.
Characterization of the enzymatic mechanism of gamma-momorcharin, a novel ribosome-inactivating protein with lower molecular weight of 11,500 purified from the seeds of bitter gourd (Momordica charantia).
Biochem Biophys Res Commun.    impact factor:   3.161
1996;  229(1): 287-94

11:  Lappi DA, Esch FS, Barbieri L, Stirpe F, Soria M.
Characterization of a Saponaria officinalis seed ribosome-inactivating protein: immunoreactivity and sequence homologies.
Biochem Biophys Res Commun.    impact factor:   3.161
1985;  129(3): 934-42

12:  Vesely DL, Graves WR, Lo TM, Fletcher MA, Levey GS.
Isolation of a guanylate cyclase inhibitor from the balsam pear (Momordica charantia abreviata).
Biochem Biophys Res Commun.    impact factor:   3.161
1977;  77(4): 1294-9

13:  Fong WP, Mock WY, Ng TB.
Intrinsic ribonuclease activities in ribonuclease and ribosome-inactivating proteins from the seeds of bitter gourd.
Int J Biochem Cell Biol.    impact factor:   2.91
2000;  32(5): 571-7

14:  Huang B, Ng TB, Fong WP, Wan CC, Yeung HW.
Isolation of a trypsin inhibitor with deletion of N-terminal pentapeptide from the seeds of Momordica cochinchinensis, the Chinese drug mubiezhi.
Int J Biochem Cell Biol.    impact factor:   2.91
1999;  31(6): 707-15

15:  Nakagawa A, Tanaka I, Sakai R, Nakashima T, Funatsu G, Kimura M.
Crystal structure of a ribonuclease from the seeds of bitter gourd (Momordica charantia) at 1.75 A resolution.
Biochim Biophys Acta.    impact factor:   2.59
1999;  1433(1-2): 253-60

16:  Neumann GM, Condron R, Polya GM.
Purification and sequencing of napin-like protein small and large chains from Momordica charantia and Ricinus communis seeds and determination of sites phosphorylated by plant Ca(2+)-dependent protein kinase.
Biochim Biophys Acta.    impact factor:   2.59
1996;  1298(2): 223-40

17:  Bolognesi A, Barbieri L, Carnicelli D, Abbondanza A, Cenini P, Falasca AI, Dinota A, Stirpe F.
Purification and properties of a new ribosome-inactivating protein with RNA N-glycosidase activity suitable for immunotoxin preparation from the seeds of Momordica cochinchinensis.
Biochim Biophys Acta.    impact factor:   2.59
1989;  993(2-3): 287-92

18:  Horejsi V, Ticha M, Novotny J, Kocourek J.
Studies on lectins. XLVII. Some properties of D-galactose binding lectins isolated from the seeds of Butea frondosa, Erythrina indica and Momordica charantia.
Biochim Biophys Acta.    impact factor:   2.59
1980;  623(2): 439-48

19:  Dhar P, Ghosh S, Bhattacharyya DK.
Dietary effects of conjugated octadecatrienoic fatty acid (9 cis, 11 trans, 13 trans) levels on blood lipids and nonenzymatic in vitro lipid peroxidation in rats.
Lipids.    impact factor:   2.04
1999;  34(2): 109-14

20:  Tsang KY, Ng TB.
Isolation and characterization of a new ribosome inactivating protein, momorgrosvin, from seeds of the monk's fruit Momordica grosvenorii.
Life Sci.    impact factor:   1.774
2001;  68(7): 773-84

21:  Valbonesi P, Barbieri L, Bolognesi A, Bonora E, Polito L, Stirpe F.
Preparation of highly purified momordin II without ribonuclease activity.
Life Sci.    impact factor:   1.774
1999;  65(14): 1485-91

22:  Fong WP, Poon YT, Wong TM, Mock JW, Ng TB, Wong RN, Yao QZ, Yeung HW.
A highly efficient procedure for purifying the ribosome-inactivating proteins alpha- and beta-momorcharins from Momordica charantia seeds, N-terminal sequence comparison and establishment of their N-glycosidase activity.
Life Sci.    impact factor:   1.774
1996;  59(11): 901-9

23:  Parkash A, Ng TB, Tso WW.
Purification and characterization of charantin, a napin-like ribosome-inactivating peptide from bitter gourd (Momordica charantia) seeds.
J Pept Res.    impact factor:   1.638
2002;  59(5): 197-202

24:  Singh A, Singh SP, Bamezai R.
Postnatal efficacy of Momordica charantia peel, pulp, seed and whole fruit extract in the detoxication pathway of suckling neonates and lactating mice.
Cancer Lett.    impact factor:   1.518
1998;  122(1-2): 121-6

25:  Kamesaki T, Omi T, Kajii E, Ikemoto S.
New method of detecting the lectin activity of Momordica charantia.
Vox Sang.    impact factor:   1.445
1990;  58(4): 307-8

26:  Jiratchariyakul W, Wiwat C, Vongsakul M, Somanabandhu A, Leelamanit W, Fujii I, Suwannaroj N, Ebizuka Y.
HIV inhibitor from Thai bitter gourd.
Planta Med.    impact factor:   1.438
2001;  67(4): 350-3

27:  Ali L, Khan AK, Mamun MI, Mosihuzzaman M, Nahar N, Nur-e-Alam M, Rokeya B.
Studies on hypoglycemic effects of fruit pulp, seed, and whole plant of Momordica charantia on normal and diabetic model rats.
Planta Med.    impact factor:   1.438
1993;  59(5): 408-12

28:  Ng TB, Wong CM, Li WW, Yeung HW.
A steryl glycoside fraction from Momordica charantia seeds with an inhibitory action on lipid metabolism in vitro.
Biochem Cell Biol.    impact factor:   1.268
1986;  64(8): 766-71

29:  Ng TB, Wong CM, Li WW, Yeung HW.
Peptides with antilipolytic and lipogenic activities from seeds of the bitter gourd Momordica charantia (family Cucurbitaceae).
Gen Pharmacol.    impact factor:   1.105
1987;  18(3): 275-81

30:  Dhar P, Bhattacharyya DK.
Nutritional characteristics of oil containing conjugated octadecatrienoic fatty acid.
Ann Nutr Metab.    impact factor:   1.057
1998;  42(5): 290-6

31:  Aoki H, Kieu NT, Kuze N, Tomisaka K, Van Chuyen N.
Carotenoid pigments in GAC fruit (Momordica cochinchinensis SPRENG).
Biosci Biotechnol Biochem.    impact factor:   1.039
2002;  66(11): 2479-82

32:  Numata T, Kashiba T, Hino M, Funatsu G, Ishiguro M, Yamasaki N, Kimura M.
Expression and mutational analysis of amino acid residues involved in catalytic activity in a ribonuclease MC1 from the seeds of bitter gourd.
Biosci Biotechnol Biochem.    impact factor:   1.039
2000;  64(3): 603-5

33:  Minami Y, Islam MR, Funatsu G.
Chemical modifications of momordin-a and luffin-a, ribosome-inactivating proteins from the seeds of Momordica charantia and Luffa cylindrica: involvement of His140, Tyr165, and Lys231 in the protein-synthesis inhibitory activity.
Biosci Biotechnol Biochem.    impact factor:   1.039
1998;  62(5): 959-64

34:  Miura S, Funatsu G.
Isolation and amino acid sequences of two trypsin inhibitors from the seeds of bitter gourd (Momordica charantia).
Biosci Biotechnol Biochem.    impact factor:   1.039
1995;  59(3): 469-73

35:  Singh A, Singh SP, Bamezai R.
Momordica charantia (Bitter Gourd) peel, pulp, seed and whole fruit extract inhibits mouse skin papillomagenesis.
Toxicol Lett.    impact factor:   .773
1998;  94(1): 37-46

36:  Padma P, Komath SS, Swamy MJ.
Fluorescence quenching and time-resolved fluorescence studies on Momordica charantia (bitter gourd) seed lectin.
Biochem Mol Biol Int.    impact factor:   .77
1998;  45(5): 911-22

37:  Komath SS, Nadimpalli SK, Swamy MJ.
Purification in high yield and characterisation of the galactose-specific lectin from the seeds of snake gourd (Trichosanthes anguina).
Biochem Mol Biol Int.    impact factor:   .77
1996;  39(2): 243-52

38:  De Shan M, Hu LH, Chen ZL.
A new multiflorane triterpenoid ester from Momordica cochinchinensis Spreng.
Nat Prod Lett.    impact factor:   .732
2001;  15(2): 139-45

39:  Ramana S, Biswas AK, Kundu S, Saha JK, Yadava RB.
Effect of distillery effluent on seed germination in some vegetable crops.
Bioresour Technol.    impact factor:   .7
2002;  82(3): 273-5

40:  Naseem MZ, Patil SR, Patil SR, Ravindra, Patil RS.
Antispermatogenic and androgenic activities of Momordica charantia (Karela) in albino rats.
J Ethnopharmacol.    impact factor:   .687
1998;  61(1): 9-16

41:  Tennekoon KH, Jeevathayaparan S, Angunawala P, Karunanayake EH, Jayasinghe KS.
Effect of Momordica charantia on key hepatic enzymes.
J Ethnopharmacol.    impact factor:   .687
1994;  44(2): 93-7

42:  Biswas AR, Ramaswamy S, Bapna JS.
Analgesic effect of Momordica charantia seed extract in mice and rats.
J Ethnopharmacol.    impact factor:   .687
1991;  31(1): 115-8

43:  Wong CM, Yeung HW, Ng TB.
Screening of Trichosanthes kirilowii, Momordica charantia and Cucurbita maxima (family Cucurbitaceae) for compounds with antilipolytic activity.
J Ethnopharmacol.    impact factor:   .687
1985;  13(3): 313-21

44:  Ng TB, Wong CM, Li WW, Yeung HW.
Acid-ethanol extractable compounds from fruits and seeds of the bitter gourd Momordica charantia: effects on lipid metabolism in isolated rat adipocytes.
Am J Chin Med.    impact factor:   .583
1987;  15(1-2): 31-42

45:  Kubota K, Sato M, Murakami T, Yamagishi T.
[Pharmacological studies on the saponin isolated from the seed of Momordica cochinchinensis Sprenger]
Yakugaku Zasshi.    impact factor:   .238
1971;  91(2): 174-9

46:  Numata T, Kimura M.
Contribution of Gln9 and Phe80 to substrate binding in ribonuclease MC1 from bitter gourd seeds.
J Biochem (Tokyo).    impact factor:   0
2001;  130(5): 621-6

47:  Cahoon EB, Carlson TJ, Ripp KG, Schweiger BJ, Cook GA, Hall SE, Kinney AJ.
Biosynthetic origin of conjugated double bonds: production of fatty acid components of high-value drying oils in transgenic soybean embryos.
Proc Natl Acad Sci U S A.    impact factor:   0
1999;  96(22): 12935-40

48:  Hamato N, Koshiba T, Pham TN, Tatsumi Y, Nakamura D, Takano R, Hayashi K, Hong YM, Hara S.
Trypsin and elastase inhibitors from bitter gourd (Momordica charantia LINN.) seeds: purification, amino acid sequences, and inhibitory activities of four new inhibitors.
J Biochem (Tokyo).    impact factor:   0
1995;  117(2): 432-7

49:  Kimura Y, Minami Y, Tokuda T, Nakajima S, Takagi S, Funatsu G.
Primary structures of N-linked oligosaccharides of momordin-a, a ribosome-inactivating protein from Momordica charantia seeds.
Agric Biol Chem.    impact factor:   0
1991;  55(8): 2031-6

50:  Yeung HW, Li WW, Ng TB.
Isolation of a ribosome-inactivating and abortifacient protein from seeds of Luffa acutangula.
Int J Pept Protein Res.    impact factor:   0
1991;  38(1): 15-9

51:  Omi T, Kamesaki T, Kajii E, Ikemoto S.
Method for detecting the lectin activity of Momordica charantia transferred from micro two-dimensional electrophoretic gel on to nitrocellulose.
J Chromatogr.    impact factor:   0
1991;  570(2): 399-405

52:  Zhu ZJ, Zhong ZC, Luo ZY, Xiao ZY.
[Studies on the active constituents of Momordica charantia L]
Yao Xue Xue Bao.    impact factor:   0
1990;  25(12): 898-903

53:  Hara S, Makino J, Ikenaka T.
Amino acid sequences and disulfide bridges of serine proteinase inhibitors from bitter gourd (Momordica charantia LINN.) seeds.
J Biochem (Tokyo).    impact factor:   0
1989;  105(1): 88-91

54:  Montecucchi PC, Lazzarini AM, Barbieri L, Stirpe F, Soria M, Lappi D.
N-terminal sequence of some ribosome-inactivating proteins.
Int J Pept Protein Res.    impact factor:   0
1989;  33(4): 263-7

55:  Kedar P, Chakrabarti CH.
Effects of bittergourd (Momordica charantia) seed & glibenclamide in streptozotocin induced diabetes mellitus.
Indian J Exp Biol.    impact factor:   0
1982;  20(3): 232-5

56:  Li SS.
Purification and partial characterization of two lectins from Momordica charantia.
Experientia.    impact factor:   0
1980;  36(5): 524-7

57:  Licastro F, Franceschi C, Barbieri L, Stirpe F.
Toxicity of Momordica charantia lectin and inhibitor for human normal and leukaemic lymphocytes.
Virchows Arch B Cell Pathol Incl Mol Pathol.    impact factor:   0
1980;  33(3): 257-65

58:  Li SS.
Purification and characterization of seed storage proteins from Momordica charantia.
Experientia.    impact factor:   0
1977;  33(7): 895-6

59:  West ME, Sidrak GH, Street SP.
The anti-growth properties of extracts from Momordica charantia L.
West Indian Med J.    impact factor:   0
1971;  20(1): 25-34


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