| ID |
Name |
Structure |
Top 10 Available References (order by impact factor) |
Molecular Target(s) |
| 1 | Compound ID:2
ABIETIC ACID
NSC#:13163
Activity Tested(uM): 35.73NSC#:25149 Cell Data(>1uM)
NSC#:58970
NSC#:154789
NSC#:224312
NSC#:224316
NSC#:226139
Aldrich#:00010
Aldrich#:165026
Aldrich#:A9424 |
C20H30O2 302.45
| 1: Vogel BS, Wildung MR, Vogel G, Croteau R.
Abietadiene synthase from grand fir (Abies grandis). cDNA isolation, characterization, and bacterial expression of a bifunctional diterpene cyclase involved in resin acid biosynthesis.
J Biol Chem. impact factor: 7.666
1996; 271(38): 23262-8
2: Imaizumi Y, Sakamoto K, Yamada A, Hotta A, Ohya S, Muraki K, Uchiyama M, Ohwada T.
Molecular basis of pimarane compounds as novel activators of large-conductance Ca(2+)-activated K(+) channel alpha-subunit.
Mol Pharmacol. impact factor: 5.465
2002; 62(4): 836-46
3: Peters RJ, Flory JE, Jetter R, Ravn MM, Lee HJ, Coates RM, Croteau RB.
Abietadiene synthase from grand fir (Abies grandis): characterization and mechanism of action of the "pseudomature" recombinant enzyme.
Biochemistry. impact factor: 4.493
2000; 39(50): 15592-602
4: Funk C, Lewinsohn E, Vogel BS, Steele CL, Croteau R.
Regulation of Oleoresinosis in Grand Fir (Abies grandis) (Coordinate Induction of Monoterpene and Diterpene Cyclases and Two Cytochrome P450-Dependent Diterpenoid Hydroxylases by Stem Wounding).
Plant Physiol. impact factor: 4.434
1994; 106(3): 999-1005
5: Cross BE, Myers PL.
The bacterial transformation of abietic acid.
Biochem J. impact factor: 4.349
1968; 108(2): 303-10
| |
| 2 | Compound ID:4
ABSCISIC ACID
NSC#:146877
Activity Tested(uM): 100NSC#:148832 Cell Data(>1uM)
Aldrich#:00012
Aldrich#:862169
Aldrich#:A0560
Aldrich#:A1012
Aldrich#:A1049
Aldrich#:A4906
Aldrich#:A7383
Aldrich#:A8451
Aldrich#:R277282 |
C15H20O4 264.32
| 1: Abe H, Urao T, Ito T, Seki M, Shinozaki K, Yamaguchi-Shinozaki K.
Arabidopsis AtMYC2 (bHLH) and AtMYB2 (MYB) Function as Transcriptional Activators in Abscisic Acid Signaling.
Plant Cell. impact factor: 10.463
2003; 15(1): 63-78
2: Casaretto J, Ho TH.
The Transcription Factors HvABI5 and HvVP1 Are Required for the Abscisic Acid Induction of Gene Expression in Barley Aleurone Cells.
Plant Cell. impact factor: 10.463
2003; 15(1): 271-84
3: Zhu J, Gong Z, Zhang C, Song CP, Damsz B, Inan G, Koiwa H, Zhu JK, Hasegawa PM, Bressan RA.
OSM1/SYP61: a syntaxin protein in Arabidopsis controls abscisic acid-mediated and non-abscisic acid-mediated responses to abiotic stress.
Plant Cell. impact factor: 10.463
2002; 14(12): 3009-28
4: Jung JY, Kim YW, Kwak JM, Hwang JU, Young J, Schroeder JI, Hwang I, Lee Y.
Phosphatidylinositol 3- and 4-phosphate are required for normal stomatal movements.
Plant Cell. impact factor: 10.463
2002; 14(10): 2399-412
5: Zheng ZL, Nafisi M, Tam A, Li H, Crowell DN, Chary SN, Schroeder JI, Shen J, Yang Z.
Plasma membrane-associated ROP10 small GTPase is a specific negative regulator of abscisic acid responses in Arabidopsis.
Plant Cell. impact factor: 10.463
2002; 14(11): 2787-97
| |
| 3 | Compound ID:6
ACACETIN
NSC#:76061
Aldrich#:00017 |
C16H12O5 284.27
| 1: Boege F, Straub T, Kehr A, Boesenberg C, Christiansen K, Andersen A, Jakob F, Kohrle J.
Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I.
J Biol Chem. impact factor: 7.666
1996; 271(4): 2262-70
2: Fiorani M, De Sanctis R, De Bellis R, Dacha M.
Intracellular flavonoids as electron donors for extracellular ferricyanide reduction in human erythrocytes.
Free Radic Biol Med. impact factor: 4.116
2002; 32(1): 64-72
3: Chen YT, Zheng RL, Jia ZJ, Ju Y.
Flavonoids as superoxide scavengers and antioxidants.
Free Radic Biol Med. impact factor: 4.116
1990; 9(1): 19-21
4: Wenzel U, Kuntz S, Daniel H.
Flavonoids with epidermal growth factor-receptor tyrosine kinase inhibitory activity stimulate PEPT1-mediated cefixime uptake into human intestinal epithelial cells.
J Pharmacol Exp Ther. impact factor: 3.3
2001; 299(1): 351-7
5: Bylka W, Franski R, Stobiecki M.
Differentiation between isomeric acacetin-6-C-(6"-O-malonyl)glucoside and acacetin-8-C-(6"-O-malonyl)glucoside by using low-energy CID mass spectra.
J Mass Spectrom. impact factor: 3.167
2002; 37(6): 648-50
| |
| 4 | Compound ID:9
ACANTHAMOLIDE
NSC#:280452
|
C19H25NO5 347.41
| no reference available. | |
| 5 | Compound ID:13
ACANTHOLIDE
NSC#:277282
|
C19H24O6 348.39
| 1: Lotter H, Wagner H, Saleh AA, Cordell GA, Farnsworth NR.
Potential anticancer agents, XI. X-ray structure determination of acantholide.
Z Naturforsch [C]. impact factor: .709
1979; 34(9-10): 677-82
| |
| 6 | Compound ID:15
ACANTHOSIDE D
NSC#:16757
|
C34H46O18 742.72
| 1: Yoshikawa K, Eiko K, Mimura N, Kondo Y, Arihara S.
Hovetrichosides C-G, five new glycosides of two auronols, two neolignans, and a phenylpropanoid from the bark of Hovenia trichocarea.
J Nat Prod. impact factor: 1.652
1998; 61(6): 786-90
2: Jiang YT, Xu SX, Gu XH, Ren L, Chen YJ, Yao XS, Miao ZC.
[Studies on the chemical constituents from Aralia elata]
Yao Xue Xue Bao. impact factor: 0
1992; 27(7): 528-32
| |
| 7 | Compound ID:16
ACANTHOSPERMAL A
NSC#:277278
|
C23H30O8 434.48
| no reference available. | |
| 8 | Compound ID:17
ACANTHOSPERMOLIDE
NSC#:255989
|
C20H26O6 362.42
| no reference available. | |
| 9 | Compound ID:20
ACETAL
NSC#:227930
Aldrich#:176958
Aldrich#:81890 |
C7H16O2 132.2
| 1: Guindon Y, Ogilvie WW, Bordeleau J, Cui WL, Durkin K, Gorys V, Juteau H, Lemieux R, Liotta D, Simoneau B, Yoakim C.
Opening of Tartrate Acetals Using Dialkylboron Bromide: Evidence for Stereoselectivity Downstream from Ring Fission.
J Am Chem Soc. impact factor: 5.537
2003; 125(2): 428-436
2: Murahashi S, Imada Y, Kawakami T, Harada K, Yonemushi Y, Tomita N.
Enantioselective addition of ketene silyl acetals to nitrones catalyzed by chiral titanium complexes. Synthesis of optically active beta-amino acids.
J Am Chem Soc. impact factor: 5.537
2002; 124(12): 2888-9
3: Fletcher MT, Wood BJ, Brereton IM, Stok JE, De Voss JJ, Kitching W.
(18)O]-oxygen incorporation reveals novel pathways in spiroacetal biosynthesis by Bactrocera cacuminata and B. cucumis.
J Am Chem Soc. impact factor: 5.537
2002; 124(26): 7666-7
4: Nishikawa T, Asai M, Isobe M.
Asymmetric total synthesis of 11-deoxytetrodotoxin, a naturally occurring congener.
J Am Chem Soc. impact factor: 5.537
2002; 124(26): 7847-52
5: Kim S, Lim CJ, Song C, Chung WJ.
Novel radical alkylation of carboxylic imides.
J Am Chem Soc. impact factor: 5.537
2002; 124(48): 14306-7
| |
| 10 | Compound ID:21
ACETAMIDE
NSC#:25945
NSC#:244792
Aldrich#:00160
Aldrich#:122637
Aldrich#:150703
Aldrich#:487775
Aldrich#:A0500 |
C2H5NO 59.07
| 1: Kleymann G, Fischer R, Betz UA, Hendrix M, Bender W, Schneider U, Handke G, Eckenberg P, Hewlett G, Pevzner V, Baumeister J, Weber O, Henninger K, Keldenich J, Jensen A, Kolb J, Bach U, Popp A, Maben J, Frappa I, Haebich D, Lockhoff O, Rubsamen-Waigmann H.
New helicase-primase inhibitors as drug candidates for the treatment of herpes simplex disease.
Nat Med. impact factor: 26.584
2002; 8(4): 392-8
2: Chavez JC, LaManna JC.
Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1.
J Neurosci. impact factor: 8.955
2002; 22(20): 8922-31
3: Schroder D, Loos J, Thissen R, Dutuit O, Mourgues P, Audier HE, Lifshitz C, Schwarz H.
Barrier height titration by tunable photoionization combined with chemical monitoring: unimolecular keto/enol tautomerization of the acetamide cation radical.
Angew Chem Int Ed Engl. impact factor: 7.996
2002; 41(15): 2748-51
4: Rappert A, Biber K, Nolte C, Lipp M, Schubel A, Lu B, Gerard NP, Gerard C, Boddeke HW, Kettenmann H.
Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia.
J Immunol. impact factor: 7.145
2002; 168(7): 3221-6
5: Richard JP, Williams G, O'Donoghue AC, Amyes TL.
Formation and stability of enolates of acetamide and acetate anion: an Eigen plot for proton transfer at alpha-carbonyl carbon.
J Am Chem Soc. impact factor: 5.537
2002; 124(12): 2957-68
| |